Results 151 to 160 of about 4,153 (179)

Modulation of the tumor microenvironment by the ubiquitin-proteasome system in colorectal cancer. [PDF]

J Transl Med
Wang X, Ren Y, Song R, Liu J, Zhou Y, Yang S, Liu Y, Lei Y, Zhao X.   +8 more
europepmc   +1 more source

USP14 Mediates Molecular Mechanisms Regulating Aortic Valve Stenosis Through Ubiquitination. [PDF]

J Cell Mol Med
Yang Y, Yao BC, Li JH, Chen QL, Jiang N, Wang LQ, Guo ZG.   +6 more
europepmc   +1 more source

Herpesviruses and autophagy: An intracellular conflict. [PDF]

Virulence
Sun Q, Zhang L, Chen J, Fu Q.
europepmc   +1 more source

PSMD11 facilitates immune escape by recruiting USP14 to modulate the deubiquitinating degradation of PD-L1 in non-small cell lung cancer. [PDF]

J Thorac Dis
Xi Y, Yang P, Zeng J, Zhou Y, Patel AJ, Shen W, Liu X, Rajandram R, Krishnasamy S.   +8 more
europepmc   +1 more source

USP14 inhibition corrects an in vivo model of impaired mitophagy [PDF]

EMBO Molecular Medicine, 2018
Mitochondrial autophagy or mitophagy is a key process that allows selective sequestration and degradation of dysfunctional mitochondria to prevent excessive reactive oxygen species, and activation of cell death.
Elena Marchesan, Federico Caicci, Luigi Bubacco   +2 more
exaly   +5 more sources

USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination [PDF]

Autophagy, 2018
Recent reports have made important revelations, uncovering direct regulation of DNA damage response (DDR)-associated proteins and chromatin ubiquitination (Ubn) by macroautophagy/autophagy.
Mónica Venere, Matthew K Summers, Alexandru Almasan   +2 more
exaly   +4 more sources

Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling [PDF]

Oncogenesis, 2013
Dishevelled (Dvl) is a key regulator of Wnt signaling both in the canonical and non-canonical pathways. Here we report the identification of a regulatory domain of ubiquitination (RDU) in the C-terminus of Dvl. Mutations in the RDU resulted in accumulation of polyubiquitinated forms of Dvl, which were mainly K63 linked.
Madelon M Maurice, Min Jae Lee
exaly   +6 more sources

USP14 increases the sensitivity of retinoblastoma to cisplatin by mediating the ferroptosis

Naunyn-Schmiedeberg's Archives of Pharmacology
AbstractThe aim of this study is to explore the function of USP14 on the sensitivity of retinoblastoma (RB) to cisplatin (DDP) and the underlying mechanism. USP14 was knockdown in Y79 cells by transfecting three siRNAs (si-USP14-1, si-USP14-2, and si-USP14-3), with si-USP14 NC as the negative control.
Jiayue Li, Yong Chai, Qifang Jin
exaly   +3 more sources