Results 131 to 140 of about 4,153 (179)

Structural mechanism of 26S proteasome regulation and its pharmacological modulation. [PDF]

J Biol Chem
Pei K, Zhao L, Hu J, Mao Y.
europepmc   +1 more source

Disrupting USP14-mediated PARP1 dynamics reinstates MIC-A/B-driven antigen-independent CD8⁺ T cell killing in glioma. [PDF]

Sci Adv
Wang M, Yu S, Zhang C, Cheng Q, Gong Z, Li X, Huang T, Wang X, Jiang X, Li J.   +9 more
europepmc   +1 more source

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome. [PDF]

Nat Commun
Casasampere M, Carneros H, Roda T, Zuin A, Gallisà-Suñé N, González-Artero A, Coll-Martínez B, Abad JL, Alqahtani A, Casas J, Fernández-Nogueira P, Delgado A, Bujons J, Fabriàs G, Crosas B.   +14 more
europepmc   +1 more source

Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination. [PDF]

J Transl Med
Yunxin L, Xirui X, Xinyi Z, Chenjing W, Ting Z, Kanghui F, Haixia Y, Zude C, Wan H, Yubing Z, Xianjun F.   +10 more
europepmc   +1 more source

CircKIAA1617 promotes stemness via USP14/PGRMC1-mediated autophagy and lipid metabolism reprogramming in ER-positive breast cancer. [PDF]

Mol Cancer
Yang J, Li Y, Wang Z, Sun Y, He Y, Niu T, Liang Y, Chen X, Chen T, Han D, Zhang N, Zhao W, Chen B, Wang L, Luo D, Li X, Yang Q.   +16 more
europepmc   +1 more source

Pathological role of deubiquitinating enzymes in lung cancer: recent insights and advances. [PDF]

Am J Cancer Res
Huang Q, Zhang Z, Wang YN, Li MM, Han XH, Han XJ, Li QG.   +6 more
europepmc   +1 more source

Novel Small-Molecule Analogues of IU1 Ameliorate Amyloid-β Mediated Toxicity in Alzheimer's Disease Cell and Worm Models. [PDF]

Int J Mol Sci
Ariyath A, Arigo FD, Wallach I, Fernando WMADB, Martins RN, Bharadwaj P.   +5 more
europepmc   +1 more source

Ubiquitin-specific proteases in ovarian cancer: molecular mechanisms and therapeutic implications. [PDF]

J Ovarian Res
Deng L, Jiang Y, Wang D, Yu J, Wu L.
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival. [PDF]

Mol Oncol
Almuhanna HNB, Hay J, Moles MW, Clarke L, Cassels J, Sefcick A, McCaig AM, Jørgensen HG, Michie AM.   +8 more
europepmc   +1 more source

Editorial: Iron dysregulation, oxidative stress, and inflammation: mechanisms and therapeutic insights. [PDF]

Front Mol Biosci
Cutone A, Ianiro G, Fiorillo C.
europepmc   +1 more source