Results 121 to 130 of about 3,826 (176)

In vivo characterization in flies of new USP14 inhibitors

openLa proteostasi è la regolazione dinamica di un proteoma funzionale per garantire il corretto ripiegamento delle proteine di nuova sintesi e la degradazione di quelle mal ripiegate.
VIVIANI, PIETRO
core  

Macrophage-derived IL-6 reprograms lipid metabolism to promote colorectal cancer development through USP14-mediated FASN deubiquitination. [PDF]

J Transl Med
Yunxin L, Xirui X, Xinyi Z, Chenjing W, Ting Z, Kanghui F, Haixia Y, Zude C, Wan H, Yubing Z, Xianjun F.   +10 more
europepmc   +1 more source

CircKIAA1617 promotes stemness via USP14/PGRMC1-mediated autophagy and lipid metabolism reprogramming in ER-positive breast cancer. [PDF]

Mol Cancer
Yang J, Li Y, Wang Z, Sun Y, He Y, Niu T, Liang Y, Chen X, Chen T, Han D, Zhang N, Zhao W, Chen B, Wang L, Luo D, Li X, Yang Q.   +16 more
europepmc   +1 more source

Novel Small-Molecule Analogues of IU1 Ameliorate Amyloid-β Mediated Toxicity in Alzheimer's Disease Cell and Worm Models. [PDF]

Int J Mol Sci
Ariyath A, Arigo FD, Wallach I, Fernando WMADB, Martins RN, Bharadwaj P.   +5 more
europepmc   +1 more source

Deubiquitinating enzymes in cervical cancer: Molecular mechanisms and therapeutic implications (Review). [PDF]

Int J Oncol
Pei CZ, Song XX, Xu H, Baek KH.
europepmc   +1 more source

Spotlights on ubiquitin-specific proteases in lung cancer: from multifaceted pathophysiological mechanisms to potential therapeutic targets. [PDF]

PeerJ
Shen X, Wang R, Su F, Guo J, Zhao D, Yuan F, Zhang T, Hou X.   +7 more
europepmc   +1 more source

[The miR-30b/USP14 axis regulates mitophagy via a non-PINK1/Parkin pathway in neuronal oxygen-glucose deprivation/reoxygenation injury]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Bei YH, Yu K, Wang X.
europepmc   +1 more source

Ubiquitination-dependent regulation of ferroptosis in ischemic heart and brain. [PDF]

Redox Biol
Zhang YY, Long XY, Tian J, Luo XJ, Peng J.   +4 more
europepmc   +1 more source

Ubiquitination and deubiquitination as critical modulators of NSCLC tumorigenesis and drug resistance. [PDF]

Discov Oncol
Ramalingam PS, Afzal M, Rekha MM, Sahoo S, Pandey SN, Maji C, Goyal K, Ali H, Singh SK, Gupta G, Hussain MS, Balakrishnan P, Arumugam S.   +12 more
europepmc   +1 more source

Molecular targeting of the deubiquitinase USP14 to circumvent cisplatin resistance in ovarian carcinoma and identification of novel inhibitors. [PDF]

Cancer Drug Resist
Corno C, Russo D, Pignotti F, De Giorgi F, Penna I, Saccoliti F, Costantino M, Mirra L, Pettinari P, Carenini N, Corna E, Perta N, Ciniselli CM, Pratesi P, Scarpelli R, Bertozzi F, Verderio P, Beretta GL, Di Muccio G, Di Marino D, Bandiera T, Perego P.   +21 more
europepmc   +1 more source