Results 21 to 30 of about 161,532 (251)
Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization
Vaccine: X, 2019 Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata +7 more
doaj +1 more source
Toward QbD Process Understanding on DNA Vaccine Purification Using Design of Experiment
Frontiers in Bioengineering and Biotechnology, 2021 DNA vaccines, the third generation of vaccines, are a promising therapeutic option for many diseases as they offer the customization of their ability on protection and treatment with high stability.
Lalintip Hocharoen +2 more
doaj +1 more source
Проблемы особо опасных инфекций, 2010 With the development of various branches of medicine and biology the classical ideas about means to prevent infectious diseases have changed. Nowadays in different countries of the world, investigations are carried out intensively in the sphere of ...
Yu. A. Popov, N. I. Mikshis
doaj +1 more source
Allergy, 1999 Chronic infections with hepatitis B (HBV) and hepatitis C (HCV) virus are worldwide problems often leading to the development of chronic liver disease and hepatocellular carcinoma. Genetic immunizations with DNA encoding for structural and nonstructural proteins of HCV and HBV in experimental mice generate a broad base CD4+ and CD8+ cellular immune ...
H L, Spiegelberg, E, Raz
openaire +4 more sources
Recent advances in delivery of veterinary DNA vaccines against avian pathogens
Veterinary Research, 2019 Veterinary vaccines need to have desired characteristics, such as being effective, inexpensive, easy to administer, suitable for mass vaccination and stable under field conditions.
Seyed Davoud Jazayeri, Chit Laa Poh
doaj +1 more source
A Novel Formulation Strategy to Deliver Combined DNA and VLP Based HPV Vaccine
Journal of Pharmacy & Pharmaceutical Sciences, 2019 Human papillomaviruses (HPV) are small, double-stranded DNA viruses that cause cervical cancer, the second most lethal cancer among women in the world. Currently, two vaccines are on the market for preventing HPV-caused cervical cancers and warts.
Mohammad Nasir Uddin +4 more
doaj +1 more source
Veterinární Medicína, 2023 Pseudomonas aeruginosa is an infectious pathogenic bacteria infecting many different species of animals. Currently, it lacks a commercial vaccine. In this study, three monovalent DNA vaccines (poprL, poprF, and pflgE), three bivalent combination DNA ...
Q Gong, Y Li, W Zhai, M Niu
doaj +1 more source
Manganese-based nanoadjuvants for enhancement of immune effect of DNA vaccines
Frontiers in Bioengineering and Biotechnology, 2022 As a highly pathogenic avian influenza virus, influenza A (H5N1) has been reported to infect humans, posing a major threat to both poultry industry and public health. It is an urgent need to develop a kind of effective vaccine to prevent death and reduce
Qiang Ma +9 more
doaj +1 more source
A Comparison of Plasmid DNA and mRNA as Vaccine Technologies
Vaccines, 2019 This review provides a comparison of the theoretical issues and experimental findings for plasmid DNA and mRNA vaccine technologies. While both have been under development since the 1990s, in recent years, significant excitement has turned to mRNA ...
Margaret A. Liu
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 DNA vaccines expressing codon-optimized Venezuelan equine encephalitis virus (VEEV) and Ebola virus (EBOV) glycoprotein genes provide protective immunity to mice and nonhuman primates when delivered by intramuscular (IM) electroporation (EP).
John J. Suschak +7 more
doaj +1 more source