Results 31 to 40 of about 274,774 (268)

Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives

open access: yesPharmaceutics, 2014
Intranasal delivery of DNA vaccines has become a popular research area recently. It offers some distinguished advantages over parenteral and other routes of vaccine administration.
Yingying Xu   +2 more
doaj   +1 more source

Antirabies DNA Immunization

open access: yesПроблемы особо опасных инфекций, 2010
Cited are literary data related to the development of DNA vaccines against rabies virus. Research results regarding gene vaccination of different models of laboratory animals and different ways of vaccine introduction are presented.
I. V. Tuchkov, A. K. Nikiforov
doaj   +1 more source

Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study

open access: yesFrontiers in Immunology, 2022
Current vaccination strategies against influenza focus on generating an antibody response against the viral haemagglutination surface protein, however there is increasing interest in neuraminidase (NA) as a target for vaccine development. A critical tool
Marie-Clotilde Bernard   +20 more
doaj   +1 more source

Removing N-terminal sequences in pre-S1 domain enhanced antibody and B-cell responses by an HBV large surface antigen DNA vaccine. [PDF]

open access: yesPLoS ONE, 2012
Although the use of recombinant hepatitis B virus surface (HBsAg) protein vaccine has successfully reduced global hepatitis B infection, there are still a number of vaccine recipients who do not develop detectable antibody responses.
Guohong Ge   +5 more
doaj   +1 more source

Racing against COVID-19: a vaccines strategy for Europe. Bruegel Policy Contribution Issue n˚7 | April 2020 [PDF]

open access: yes, 2020
The fast development of vaccines is an essential part of the long-term solution to COVID-19, but vaccine development has high costs and carries the risk of high failure rates.
Veugelers, Reinhilde, Zachmann, Georg.
core   +1 more source

Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]

open access: yes, 1994
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H.   +4 more
core   +1 more source

Liposome‐mediated DNA vaccination [PDF]

open access: yesFEBS Letters, 1997
Numerous reports have indicated that intramuscular injection of antigen‐coding naked plasmid DNA can trigger humoral and cell‐mediated protective immunity against infection. This follows DNA uptake by muscle fibres, leading to the expression and extracellular release of the antigen. Here it is shown for the first time that intramuscular immunization of
Gregoriadis, Gregory   +2 more
openaire   +2 more sources

Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]

open access: yes, 2010
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M.   +11 more
core   +1 more source

DNA vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2013
Since the introduction of DNA vaccines two decades ago, this attractive strategy has been hampered by its low immunogenicity in humans. Studies conducted to improve the immunogenicity of DNA vaccines have shown that understanding the mechanism of action of DNA vaccines might be the key to successfully improving their immunogenicity.
Coban, Cevayir   +4 more
openaire   +2 more sources

Cytolytic Perforin as an Adjuvant to Enhance the Immunogenicity of DNA Vaccines

open access: yesVaccines, 2019
DNA vaccines present one of the most cost-effective platforms to develop global vaccines, which have been tested for nearly three decades in preclinical and clinical settings with some success in the clinic.
Ashish C. Shrestha   +5 more
doaj   +1 more source

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