Results 41 to 50 of about 1,877,160 (342)

Influenza and memory T cells : how to awake the force [PDF]

, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen, Hartshorn, Hufford, Jin, Jordan, Luo, Mosmann, Razvi, Topham, Topham, Topham, Von Andrian, Wijburg   +12 more
core   +3 more sources

Research Progress on the Development of Porcine Reproductive and Respiratory Syndrome Vaccines

Veterinary Sciences, 2023
Simple Summary Vaccine immunization measures are mainly adopted for porcine reproductive and respiratory syndrome (PRRS) prevention. We summarize the advantages, disadvantages, and applicability of currently developed PRRSV vaccines, including modified ...
Hang Zhang, Q. Luo, Ying-jie He, Yajie Zheng, Huiyang Sha, Gan Li, Weili Kong, J. Liao, Mengmeng Zhao   +8 more
semanticscholar   +1 more source

Applications of polymer-based nanoparticles in vaccine field

Nanotechnology Reviews, 2019
Polymer-based nanoparticles have good solubility, stability, safety, and sustained release,which increases the absorption of loaded drugs, protects the drugs from degradation, and prolongs their circulation time and targeted delivery.
Guo Sihan, Fu Dongwei, Utupova Assem, Sun Dejun, Zhou Mo, Jin Zheng, Zhao Kai   +6 more
doaj   +1 more source

A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models

npj Vaccines, 2023
Opioid use disorders (OUD) and overdose are public health threats worldwide. Widespread access to highly potent illicit synthetic opioids such as fentanyl is driving the recent rise in fatal overdoses.
B. Crouse, Shannon M Miller, P. Muelken, L. Hicks, Jennifer Vigliaturo, Cheryl L. Marker, A. Guedes, P. Pentel, Jay T. Evans, M. Lesage, M. Pravetoni   +10 more
semanticscholar   +1 more source

SYNTHETIC BIOLOGY AS AN INSTRUMENT FOR DEVELOPMENT OF INNOVATIVE VACCINES FOR PROPHYLAXIS OF BACTERIAL INFECTIONS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
For many decades, live vaccines remain the most effective means for prophylaxis of bacterial infections. Until recently, the main source of vaccine strains were empirically selected bacteria, virulence of which was attenuated due to natural mutations ...
A. V. Kolesnikov, A. V. Kozyr, L. G. Shemyakin, LA. .. Lisitskaya, M. A. Marin, A. K. Ryabko, LA. .. Dyatlov   +6 more
doaj   +1 more source

An Update on mRNA-Based Viral Vaccines

Vaccines, 2021
With the success of COVID-19 vaccines, newly created mRNA vaccines against other infectious diseases are beginning to emerge. Here, we review the structural elements required for designing mRNA vaccine constructs for effective in vitro synthetic ...
Subbiah Jeeva, Ki-Hye Kim, Chong Hyun Shin, Bao-Zhong Wang, Sang-Moo Kang   +4 more
doaj   +1 more source

CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]

, 2020
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam, Ebner, Friederike, Freund, Christian, Hartmann, Susanne, Midha, Ankur, Morrison, Eliot, Álvaro-Benito, Miguel   +6 more
core   +1 more source

Dominant Antiviral CD8+ T Cell Responses Empower Prophylactic Antibody-Eliciting Vaccines Against Cytomegalovirus

Frontiers in Immunology, 2022
Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals.
Iris N. Pardieck, Suzanne van Duikeren, Dominique M. B. Veerkamp, Dena J. Brasem, Anke Redeker, Jeroen van Bergen, Wanda Han, Ferry Ossendorp, Gerben Zondag, Ramon Arens   +9 more
doaj   +1 more source

Synthetic Biodegradable Microparticle and Nanoparticle Vaccines against the Respiratory Syncytial Virus

Vaccines, 2016
Synthetic biodegradable microparticle and nanoparticle platform technology provides the opportunity to design particles varying in composition, size, shape and surface properties for application in vaccine development.
Patricia A Jorquera, R. Tripp
semanticscholar   +1 more source

Peptide-Based Vaccines for Tuberculosis

Frontiers in Immunology, 2022
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in 2020 is rising, making TB prevention and control more challenging ...
W. Gong, Chao Pan, Peng Cheng, Jie Wang, Guangyu Zhao, Xueqiong Wu   +5 more
semanticscholar   +1 more source