Results 101 to 110 of about 1,739,286 (305)
Vaccinia virus, a promising new therapeutic agent for pancreatic cancer.
Immunotherapy, 2015 The poor prognosis of pancreatic cancer patients signifies a need for radically new therapeutic strategies. Tumor-targeted oncolytic viruses have emerged as attractive therapeutic candidates for cancer treatment due to their inherent ability to ...
C. Al Yaghchi +4 more
semanticscholar +1 more source
Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
An intact signal peptide on dengue virus E protein enhances immunogenicity for CD8+ T cells and antibody when expressed from modified vaccinia Ankara [PDF]
, 2014 Dengue is a global public health concern and this is aggravated by a lack of vaccines or antiviral therapies. Despite the well-known role of CD8(+) T cells in the immunopathogenesis of Dengue virus (DENV), only recent studies have highlighted the ...
Coelho, Fabiana M. +5 more
core +1 more source
Diagnostic electron microscopy in human infectious diseases – Methods and applications
Journal of Microscopy, EarlyView.Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source
Susceptibility of different leukocyte cell types to Vaccinia virus infection
Virology Journal, 2004 Background Vaccinia virus, the prototype member of the family Poxviridae, was used extensively in the past as the Smallpox vaccine, and is currently considered as a candidate vector for new recombinant vaccines.
Sánchez-Puig Juana M +3 more
doaj +1 more source
The vaccinia virus K7 protein promotes histone methylation associated with heterochromatin formation. [PDF]
PLoS ONE, 2017 It has been well established that many vaccinia virus proteins suppress host antiviral pathways by targeting the transcription of antiviral proteins, thus evading the host innate immune system. However, whether viral proteins have an effect on the host's
Wondimagegnehu M Teferi +5 more
doaj +1 more source
Journal of Microscopy, EarlyView.Abstract In this short and popular review, we summarise some of our findings analysing the replication cycles of large DNA viruses using scanning transmission electron tomography (STEM tomography) that we applied in the laboratory of Paul Walther. It is also a tribute to a very kind and expert scientist, who recently retired.
Susanne Wieczorek +1 more
wiley +1 more source
Compact, Synthetic, Vaccinia Virus Early/Late Promoter for Protein Expression
BioTechniques, 1997 Vaccinia virus, a member of the poxvirus family, is widely used as a mammalian cell expression vector. Vaccinia virus replicates in the cytoplasm and has its own transcriptional system, making it necessary to use viral promoters.
Sekhar Chakrabarti +2 more
doaj +1 more source
Allergic airway disease in mice alters T and B cell responses during an acute respiratory poxvirus infection. [PDF]
PLoS ONE, 2013 Pulmonary viral infections can exacerbate or trigger the development of allergic airway diseases via multiple mechanisms depending upon the infectious agent.
Crystal C Walline +13 more
doaj +1 more source
Viruses, 2014 Respiratory viruses infections caused by influenza viruses, human parainfluenza virus (hPIV), respiratory syncytial virus (RSV) and coronaviruses are an eminent threat for public health.
Arwen F Altenburg +7 more
semanticscholar +1 more source