Results 21 to 30 of about 1,775,772 (324)

Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]

, 1975
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
A. V. Boand, B. Rager-Zismann, B. Vernon-Roberts, C. A. Mims, C. A. Mims, D. R. Ginder, F. B. Bang, F. R. Avila, G. B. Mackaness, J. A. Roberts, J. G. Stevens, K. T. Brunner, L. F. Reed, M. Nishmi, M. Rabinowitch, M. Rabinowitch, M. S. Hirsch, R. Benda, R. Evans, R. Gallily, R. J. North, R. M. Schultz, R. T. Johnson, S. Ueda, W. A. F. Tompkins, W. Dabrowski   +25 more
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Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus [PDF]

, 1975
VARIOUS virus infections lead to the formation of cytotoxic lymphocytes (CL), which are capable of killing virus-infected target cells1−4. Specific lysis of target cells infected with 51Cr-labelled vaccinia virus could be observed when investigating the ...
GJ Hämmerling, GM Shearer, H. ERTL, HR McFarland, I Gardner, LF Speel, M Nabholz, M Schlesinger, O Marker, RM Zinkernagel, RM Zinkernagel, RM Zinkernagel, RV Blanden, U. KOSZINOWSKI   +13 more
core   +1 more source

Effect of the deletion of genes encoding proteins of the extracellular virion form of vaccinia virus on vaccine immunogenicity and protective effectiveness in the mouse model. [PDF]

PLoS ONE, 2013
Antibodies to both infectious forms of vaccinia virus, the mature virion (MV) and the enveloped virion (EV), as well as cell-mediated immune response appear to be important for protection against smallpox.
Clement A Meseda, Joseph Campbell, Arunima Kumar, Alonzo D Garcia, Michael Merchlinsky, Jerry P Weir   +5 more
doaj   +1 more source

Vaccinia virus replication is not affected by APOBEC3 family members

Virology Journal, 2006
Background The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA intermediate during early steps of retroviral infection.
Sutter Gerd, Münk Carsten, Martinez-Fernandez Yolanda, Suezer Yasemin, Kremer Melanie, Schnierle Barbara S   +5 more
doaj   +1 more source

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan, Boyum, Brunner, Calder, Cohen, Epstein, Evans, Fulginiti, Gardner, Gardner, Glasgow, Good, Hecht, Janossy, Julius, Koszinowski, Labowskie, Lohmann-Mathes, Lundstedt, Marker, McFarland, Oldstone, Perlmann, Perlmann, Profitt, Schirrmacher, Shearer, Shortman, Speel, Steele, Ueda, Ueda, Von Pirquet, Wagner, Wagner, Zinkernagel, Zinkernagel   +36 more
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Passatempo Virus, a Vaccinia Virus Strain, Brazil

Emerging Infectious Diseases, 2005
Passatempo virus was isolated during a zoonotic outbreak. Biologic features and molecular characterization of hemagglutinin, thymidine kinase, and vaccinia growth factor genes suggested a vaccinia virus infection, which strengthens the idea of the ...
Juliana A. Leite, Betânia P. Drumond, Giliane S. Trindade, Zélia I.P. Lobato, Flávio G. da Fonseca, João R. dos Santos, Marieta C. Madureira, Maria I.M.C. Guedes, Jaqueline M.S. Ferreira, Cláudio A. Bonjardim, Paulo C.P. Ferreira, Erna G. Kroon   +11 more
doaj   +1 more source

Pre-clinical efficacy and safety of experimental vaccines based on non-replicating vaccinia vectors against yellow fever. [PDF]

PLoS ONE, 2011
BACKGROUND: Currently existing yellow fever (YF) vaccines are based on the live attenuated yellow fever virus 17D strain (YFV-17D). Although, a good safety profile was historically attributed to the 17D vaccine, serious adverse events have been reported,
Birgit Schäfer, Georg W Holzer, Alexandra Joachimsthaler, Sogue Coulibaly, Michael Schwendinger, Brian A Crowe, Thomas R Kreil, P Noel Barrett, Falko G Falkner   +8 more
doaj   +1 more source

Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics

Journal of Immunotherapy for Cancer, 2019
Cancer vaccines and oncolytic immunotherapy are promising treatment strategies with potential to provide greater clinical benefit to patients with advanced-stage cancer.
Z. Guo, B. Lu, Z. Guo, Esther Giehl, M. Feist, Enyong Dai, Weilin Liu, W. Storkus, Yukai He, Zuqiang Liu, D. Bartlett   +10 more
semanticscholar   +1 more source

Efficacy and Safety of Doubly-Regulated Vaccinia Virus in a Mouse Xenograft Model of Multiple Myeloma

Molecular Therapy: Oncolytics, 2017
Multiple myeloma is a malignancy of plasma cells of the bone marrow. Although the prognosis is variable, no curative therapy has been defined. Vaccinia virus infects cancer cells and kills such cells in a variety of ways.
Muneyoshi Futami, Kota Sato, Kanji Miyazaki, Kenshi Suzuki, Takafumi Nakamura, Arinobu Tojo   +5 more
doaj   +1 more source

Immunization of Pigs by DNA Prime and Recombinant Vaccinia Virus Boost To Identify and Rank African Swine Fever Virus Immunogenic and Protective Proteins

Journal of Virology, 2018
African swine fever virus (ASFV) causes an acute hemorrhagic fever in domestic pigs, with high socioeconomic impact. No vaccine is available, limiting options for control.
J. Jancovich, David A. G. Chapman, D. Hansen, Mark D. Robida, A. Loskutov, Felicia M. Craciunescu, A. Borovkov, K. Kibler, L. Goatley, K. King, C. Netherton, G. Taylor, B. Jacobs, K. Sykes, L. Dixon   +14 more
semanticscholar   +1 more source