Vaccinia Virus Infections in Martial Arts Gym, Maryland, USA, 2008
Vaccinia virus is an orthopoxvirus used in the live vaccine against smallpox. Vaccinia virus infections can be transmissible and can cause severe complications in those with weakened immune systems.
Christine M. Hughes+24 more
doaj +1 more source
Viruses rely on their infected host cells to provide nutrients and energy for replication. Vaccinia virus, the prototypic member of the poxviruses, which comprise many significant human and animal pathogens, prefers glutamine to glucose for efficient ...
Anil Pant, Shuai Cao, Zhilong Yang
semanticscholar +1 more source
Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus [PDF]
The murine immediate-early (IE) protein pp89 is a nonstructural virus- encoded phosphoprotein residing in the nucleus of infected cells, where it acts as transcriptional activator.
Bertholet, Christine+4 more
core +4 more sources
Construction of three strains of recombinant oncolytic vaccinia virus and their anti-tumor activity [PDF]
Objective The aim of this study is to construct a recombinant oncolytic vaccinia virus with CCL5 and SSTR2 genes and to detect its antitumor activity. Methods Recombinant vaccinia virus eukaryotic expression plasmid pSC65-CCL5-SSTR2-Luc+ was constructed.
LI Dan-yang, FANG Jing-jing, TANG Hui
doaj
Background Vaccinia viruses have emerged as attractive therapeutic candidates for cancer treatment due to their inherent ability of tumor tropism and oncolytic property.
Yuedi Ding+4 more
doaj +1 more source
Shared determinants between virus-infected and trinitrophenyl-conjugated H-2-identical target cells detected in cell-mediated lympholysis [PDF]
Infection of H-2-identical mice with either lymphocytic choriomeningitis (LCM) virus, vaccinia virus, or paramyxo (Sendai) virus resulted in the generation of specifically sensitized cytotoxic T lymphocytes (CTL).
Bevan+16 more
core +1 more source
Detection of Vaccinia Virus in Dairy Cattle Serum Samples from 2009, Uruguay
We detected orthopoxvirus in 28 of 125 serum samples collected during 2009 from cattle in Uruguay. Two samples were PCR-positive for vaccinia virus and had sequences similar to those for vaccinia virus associated with outbreaks in Brazil.
Ana Paula Moreira Franco-Luiz+10 more
doaj +1 more source
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody. [PDF]
Virotherapy using oncolytic vaccinia virus (VACV) strains is one promising new strategy for cancer therapy. We have previously reported that oncolytic vaccinia virus strains expressing an anti-VEGF (Vascular Endothelial Growth Factor) single-chain ...
Sandeep S Patil+8 more
doaj +1 more source
Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Koszinowski, Ulrich H.+4 more
core +1 more source
Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M.+11 more
core +1 more source