Results 51 to 60 of about 1,739,286 (305)

Gene duplication, gene loss, and recombination events with variola virus shaped the complex evolutionary path of historical American horsepox-based smallpox vaccines

mBio, 2023
Vaccinia virus is the active component of all modern smallpox vaccines after the mid-20th century, but it is uncertain to what extent cowpox, vaccinia, and horsepox viruses were used to produce vaccines before then.
Aline R. V. Souza, Annika Brinkmann, José Esparza, Andreas Nitsche, Clarissa R. Damaso   +4 more
doaj   +1 more source

The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]

, 2013
Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts, Alvarez, Arakawa, Bagrodia, Bernardini, Block, Boujemaa-Paterski, Chong, Chong, Diego E. Alvarez, Earl, Engelstad, Feig, Frischknecht, Fukuoka, Gasteier, Goldberg, Haglund, Hannemann, Harris, Harris, Heindl, Hervé Agaisse, Hiller, Hollinshead, Hoppe, Humphries, Isaacs, Katz, Kleba, Koka, Kovar, Krall, Lammers, Lasa, Li, Madrid, Moseley, Moseley, Newsome, Newsome, Nezami, Otomo, Parkinson, Pollard, Pring, Pruyne, Qiu, Ridley, Rietdorf, Roberts, Rolls, Romero, Röttger, Sanderson, Scaplehorn, Schmelz, Schulte, Schönichen, Schönichen, Serio, Shibata, Siripala, Skoble, Smith, Suzuki, Takeya, Tooze, van Eijl, van Eijl, Wallar, Ward, Ward, Watanabe, Weisswange, Welch, Westendorf, Westendorf, Wolffe, Wolffe   +79 more
core   +2 more sources

Virulence in murine model shows the existence of two distinct populations of Brazilian Vaccinia virus strains. [PDF]

PLoS ONE, 2008
Brazilian Vaccinia virus had been isolated from sentinel mice, rodents and recently from humans, cows and calves during outbreaks on dairy farms in several rural areas in Brazil, leading to high economic and social impact.
Jaqueline Maria Siqueira Ferreira, Betânia Paiva Drumond, Maria Isabel Maldonado Coelho Guedes, Marcelo Antônio Pascoal-Xavier, Camila Megale Almeida-Leite, Rosa Maria Esteves Arantes, Bruno Eduardo Fernandes Mota, Jônatas Santos Abrahão, Pedro Augusto Alves, Fernando Meireles Oliveira, Paulo César Peregrino Ferreira, Cláudio Antônio Bonjardim, Zélia Inês Portela Lobato, Erna Geessien Kroon   +13 more
doaj   +1 more source

Use of Vaccinia Virus Smallpox Vaccine in Laboratory and Health Care Personnel at Risk for Occupational Exposure to Orthopoxviruses - Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2015.

MMWR. Morbidity and mortality weekly report, 2016
On June 25, 2015, the Advisory Committee on Immunization Practices (ACIP) recommended routine vaccination with live smallpox (vaccinia) vaccine (ACAM2000) for laboratory personnel who directly handle 1) cultures or 2) animals contaminated or infected ...
B. Petersen, T. Harms, M. Reynolds, L. Harrison   +3 more
semanticscholar   +1 more source

Altered serological and cellular reactivity to H-2 antigens after target cell infection with vaccinia virus [PDF]

, 1975
MICE generate cytotoxic T lymphocytes (CTL) which are able to lyse virus infected target cells in vitro after infection with lymphocytic choriomeningitis virus (LCMV) and pox-viruses1−3.
BJ Alter, CC Ting, E Tsakralides, EA Boyse, F Lilly, G Berke, GD Snell, GM Shearer, H Wekerle, H. ERTL, ID Gardner, ID Gardner, J Klein, J Lesley, M Cikes, MB Widmer, PC Doherty, RM Zinkernagel, U Koszinowski, U Koszinowski, U. KOSZINOWSKI, WH Kreth   +21 more
core   +1 more source

Canine Adipose-Derived Mesenchymal Stem Cells (cAdMSCs) as a “Trojan Horse” in Vaccinia Virus Mediated Oncolytic Therapy against Canine Soft Tissue Sarcomas

Viruses, 2020
Several oncolytic viruses (OVs) including various human and canine adenoviruses, canine distemper virus, herpes-simplex virus, reovirus, and members of the poxvirus family, such as vaccinia virus and myxoma virus, have been successfully tested for canine
Ivan Petrov, Ivaylo Gentschev, Anna Vyalkova, Mohamed I. Elashry, Michele C. Klymiuk, Stefan Arnhold, Aladar A. Szalay   +6 more
doaj   +1 more source

Route-coupled pathogenicity and immunogenicity of vaccinia virus variant inoculated mice

Инфекция и иммунитет, 2021
Vaccinia virus had played a key role in the global smallpox eradication. However, in case of mass vaccination with various Vaccinia virus strains severe side effects were revealed sometimes ending up with lethal outcomes, especially in immunocompromised ...
S. N. Shchelkunov, A. A. Sergeev, A. S. Kabanov, S. N. Yakubitskyi, T. V. Bauer, S. A. Pyankov   +5 more
doaj   +1 more source

Group 2 Vaccinia Virus, Brazil

Emerging Infectious Diseases, 2012
In 2011, vaccinia virus caused an outbreak of bovine vaccinia, affecting dairy cattle and dairy workers in Brazil. Genetic and phenotypic analyses identified this isolate as distinct from others recently identified, thereby reinforcing the hypothesis ...
Felipe Lopes Assis, Iara Apolinario Borges, Paulo César Peregrino Ferreira, Cláudio Antônio Bonjardim, Giliane de Souza Trindade, Zélia Inês Portela Lobato, Maria Isabel Maldonado Guedes, Vaz Mesquita, Erna Geessien Kroon, Jônatas Santos Abrahão   +9 more
doaj   +1 more source

Oncolytic efficacy of thymidine kinase-deleted vaccinia virus strain Guang9

OncoTarget, 2017
Oncolytic virotherapy is being developed as a promising platform for cancer therapy due to its ability to lyse cancer cells in a tumor-specific manner.
L. Deng, Jun Fan, Yuedi Ding, Jue Zhang, Bin Zhou, Yi Zhang, Biao Huang   +6 more
semanticscholar   +1 more source

PCR-Based Method for the Introduction of Mutations in Genes Cloned and Expressed in Vaccinia Virus

BioTechniques, 1998
Vaccinia virus expression systems allow efficient expression of genes and facilitate functional studies of expressed proteins in cultured mammalian cells.
María del Mar Lorenzo, Rafael Blasco
doaj   +1 more source