Results 91 to 100 of about 43,537 (271)

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

open access: yesCell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao   +9 more
wiley   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

open access: yesCell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song   +4 more
wiley   +1 more source

Changes in adiponectin system after ventricular assist device in pediatric heart failure

open access: yesJHLT Open
Background: Ventricular assist device (VAD) implant represents a therapeutic option for pediatric patients with end-stage heart failure (HF). Heart unloading by VAD can modify several molecular pathways underlying cardiac function in HF.
Rosetta Ragusa   +7 more
doaj   +1 more source

Vad hjälper och vad stjälper antimobbningsarbete?

open access: yes, 2013
Såväl internationell som nationell forskning påvisar att flertalet antimobbningsprogram samt antimobbningskomponenter, som av forskare och experter förordats, i många fall kan vara ineffektiva tillika kontraeffektiva. Då varje fall av mobbning är unikt blir således metoden att bekämpa det också sådant.
openaire   +1 more source

Accented Epidermal Thinking: How Vocal Accent Reinforces the Visibility of Race

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This conceptual article introduces the notion of accented epidermal thinking, which refers to the ways in which the perception, voicing, and discussion of vocal accent all reinforce or accent the idea of race being a visual construct. The article explores how accented epidermal thinking manifests itself in three areas.
Vijay A. Ramjattan
wiley   +1 more source

The Association Between Caregiver Psychosocial Factors and Depressive Symptoms in People With Dementia: A Systematic Review and Meta‐Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To identify and evaluate the magnitude of the association between caregiver psychosocial factors and depressive symptoms among people with dementia. Design Systematic review and meta‐analysis. Methods A systematic review with meta‐analysis used a random‐effects model to estimate the effect size.
Wenjing Ning   +3 more
wiley   +1 more source

Prevalence and Modifiable Risk Factors of Dementia in People With Down Syndrome: Cross‐Sectional Study of Japan in Collaboration With the Intellectual Diversity for Goodness Research Consortium (INDIGO‐2019)

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background People with Down syndrome (DS) have a strong genetic predisposition to Alzheimer's disease (AD). However, the clinical burden and associated risk factors in diverse, non‐Western populations remain less understood. This study aimed to investigate the prevalence of dementia in Japanese adults with DS and to identify modifiable ...
Shintaro Takenoshita   +6 more
wiley   +1 more source

Letter to the Editor re: ‘How the factoid of wind turbines causing ‘vibroacoustic disease’ came to be ‘irrefutably demonstrated’

open access: yesAustralian and New Zealand Journal of Public Health, 2014
Mariana Alves‐Pereira   +1 more
doaj   +1 more source

A Computationally Efficient Mel-Filter Bank VAD Algorithm for Distributed Speech Recognition Systems

open access: yesEURASIP Journal on Advances in Signal Processing, 2005
This paper presents a novel computationally efficient voice activity detection (VAD) algorithm and emphasizes the importance of such algorithms in distributed speech recognition (DSR) systems.
Vlaj Damjan   +3 more
doaj   +1 more source

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