Results 91 to 100 of about 363,273 (339)

ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth

Advanced Science, EarlyView.
This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen, Qiao‐ling Huang, Ming‐zhi Han, Xue‐hui Hong, De‐yi Feng, Lu‐ming Yao, Wen‐bin Hong, Yue Chen, Ya‐ying Huang, Hang‐zi Chen, Qiao Wu   +10 more
wiley   +1 more source

Detect Windows Code Injection by Cross-validating Stack and VAD Information

Journal of Harbin University of Science and Technology
Windows 32/64-bit code injection attacks are a common attack technique by malware. In the field of memory forensics, the existing code injection attack detection technologies cannot handle dynamic content in terms of verification integrity, and cannot be
ZHAI Jiqiang, HAN Xu, WANG Jiaqian, SUN Haixu, YANG Hailu   +4 more
doaj   +1 more source

BAHUSANSKRUTIK VAD

, 2022
Sansruti ya sankalpanechya anek vyakhya aahet. Sankruti hi pravahi sankalpana aahe. yamadhe aata konatya shanka nahi. sanskruti shabdacha artha satatyane badalat asato.
openaire   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

Quantum dots with split enhancement gate tunnel barrier control

, 2019
We introduce a silicon metal-oxide-semiconductor quantum dot architecture based on a single polysilicon gate stack. The elementary structure consists of two enhancement gates separated spatially by a gap, one gate forming a reservoir and the other a ...
Carr, S. M., Carroll, M. S., Curry, M., Eyck, G. Ten, Lilly, M. P., Manginell, R., Pioro-Ladrière, M., Pluym, T., Rochette, S., Roy, A. -M., Rudolph, M., Ward, D., Wendt, J.   +12 more
core   +1 more source

Optimal distributed control of a nonlocal convective Cahn-Hilliard equation by the velocity in 3D [PDF]

, 2014
In this paper we study a distributed optimal control problem for a nonlocal convective Cahn--Hilliard equation with degenerate mobility and singular potential in three dimensions of space.
Rocca, Elisabetta, Sprekels, Juergen
core   +3 more sources

Evaluation of the (R)VAD+C regimen for the treatment of newly diagnosed mantle cell lymphoma. Combined results of two prospective phase II trials from the French GOELAMS group

Haematologica, 2010
Background There is currently no international consensus for first-line treatment (prior to autologous stem cell transplantation) in mantle cell lymphoma patients.
R. Gressin, S. Caulet-maugendre, E. Deconinck, O. Tournilhac, E. Gyan, M. Moles, A. Yamani, J. Cornillon, J. Rossi, S. le Gouill, G. Lepeu, G. Damaj, P. S. Celigny, H. Maisonneuve, B. Corront, J. Vilque, P. Casassus, T. Lamy, M. Colonna, P. Colombat   +19 more
semanticscholar   +1 more source

Intracellular Mechanical Stress‐Mediated Autophagy Cell Death via Nanospikes for Cancer Treatment

Advanced Science, EarlyView.
Nanospikes with tunable morphology at the nanoscale induce lysosomal membrane damage by generating localized mechanical stress, activating Galectin‐3 (Gal3)‐Trim16‐mediated autophagic cell death. Finite element analysis and laser‐triggered spike ablation enable precise control of intracellular force signaling and cytotoxicity, offering a ...
Yingze Li, Zihan Guo, Jiawei Fan, Ruimei Zhou, Jiayan Li, Zhixiang Hu, Weicheng Gu, Mengge Zheng, Chang Xu, Yichao Tang, Chang Chen, Yu Cheng   +11 more
wiley   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source