5-Valine-oxytocin and 1-Deamino-5-valine-oxytocin [PDF]
Abstract The paper reports the syntheses of 5-valine-oxytocin and 1-deamino-5-valine-oxytocin, analogues of oxytocin and 1-deamino-oxytocin which contain a valine residue in place of the asparagine residue in position 5. On assay for biological activity, 5-valine-oxytocin was found to possess approximately 0.3 unit per mg of oxytocic activity and 0.1 ...
Irving L. Schwartz, Roderich Walter
openaire +2 more sources
Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]
Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao+5 more
core
Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease [PDF]
Background: S-100B and tau protein have a high differential diagnostic potential for the diagnosis of Creutzfeldt-Jakob disease (CJD). So far there has been only limited information available about the dynamics of these parameters in the cerebrospinal ...
Barbara Ciesielczyk+18 more
core +1 more source
Incorporation in vitro of labeled amino acids into proteins of rabbit reticuloytes [PDF]
Continuing our work on the incorporation of labeled amino acids into proteins (1), we have begun a study of the incorporation in vitro of C14-labeled glycine, L-histidine, L-leucine, and L-lysine into the proteins of rabbit reticulocytes.
Borsook, Henry+4 more
core
Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy. [PDF]
Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, biallelic mutations in 31 ARS genes are known to cause recessive, early-onset severe multi-organ diseases ...
Accogli, Andrea+28 more
core +2 more sources
Studies on promoting milk protein yield by supplementation of amino acids have been globally conducted. Nevertheless, there is a lack of knowledge of what pathways affected by individual amino acid in mammary ...
Jungeun Kim+5 more
doaj +1 more source
Speex: A Free Codec For Free Speech [PDF]
The Speex project has been started in 2002 to address the need for a free, open-source speech codec. Speex is based on the Code Excited Linear Prediction (CELP) algorithm and, unlike the previously existing Vorbis codec, is optimised for transmitting speech for low latency communication over an unreliable packet network. This paper presents an overview
arxiv
A New Robust Frequency Domain Echo Canceller With Closed-Loop Learning Rate Adaptation [PDF]
One of the main difficulties in echo cancellation is the fact that the learning rate needs to vary according to conditions such as double-talk and echo path change. Several methods have been proposed to vary the learning. In this paper we propose a new closed-loop method where the learning rate is proportional to a misalignment parameter, which is in ...
arxiv +1 more source
Neighbouring residue effects on the ^(15)N chemical shifts of some aliphatic dipeptides [PDF]
The ^(15)N chemical shifts of a number of simple aliphatic dipeptides have been determined in a aqueous solution and while the amine nitrogen shift is independent of the nature of the neighbouring residue, the peptide nitrogen shift shows a marked ...
Loftus, Philip+3 more
core +1 more source
Daala: A Perceptually-Driven Next Generation Video Codec [PDF]
The Daala project is a royalty-free video codec that attempts to compete with the best patent-encumbered codecs. Part of our strategy is to replace core tools of traditional video codecs with alternative approaches, many of them designed to take perceptual aspects into account, rather than optimizing for simple metrics like PSNR.
arxiv