Results 41 to 50 of about 1,721,367 (299)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Formal Apology for Metaphysics [PDF]

open access: yes, 2018
There is an old meta-philosophical worry: very roughly, metaphysical theories have no observational consequences and so the study of metaphysics has no value.
Baron, Samuel
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Pedagogical Value From Mathematical Mistakes [PDF]

open access: yes, 2011
A real correct and mistake basically have the same point. Mistake done by student during doing mathematics problem can have the positive values and worth to develop the new mathematics concept.
Kadir , Kadir
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Implementation Of Character-Building Education In Mathematics Teaching And Learning To Create Of Human Character [PDF]

open access: yes, 2011
Character is a part of human doing. Recent, human’s character become decrease. The phenomena of the decreasing of human character are corruption, killing, and Its also happened in education. Regardless of that, education can be one of preventive solution
Gelar Dwirahayu, Gelar Dwirahayu
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

PENGARUH LOCUS OF CONTROL, EFIKASI DIRI, KEMAMPUAN MENGINGAT DAN AKTIVITAS BELAJAR TERHADAP PRESTASI BELAJAR MATEMATIKA [PDF]

open access: yes, 2006
Value of mathematics lessons in Indonesia is still relatively low when compared with other countries. The low value of mathematics can be associated with the characteristics of abstract mathematics, so that many students have difficulty in learning ...
Lestari, Vivi Kurnia
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Considering Teachers’ Beliefs, Motivation, and Emotions Regarding Teaching Mathematics With Digital Tools: The Effect of an In-Service Teacher Training

open access: yesFrontiers in Education, 2021
Mathematics teachers’ motivational and emotional orientations regarding digital tools in mathematics classrooms are key aspects influencing whether and how technology is used to teach mathematics—making the support of those characteristics one central ...
Frank Reinhold   +3 more
doaj   +1 more source

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