Results 51 to 60 of about 320,119 (385)

Multiple linear regression model was constructed based on the influencing factors of vancomycin trough concentration

Dose-Response
Objective: To evaluate the influencing factors of Vancomycin trough concentration in blood, construct an individualized Vancomycin administration model for rational use of Vancomycin. Methods: The clinical data of Vancomycin trough concentration in blood
Lin Wang, Yuhuang Wang, Chunyan Yang, Jia Jiang, Huifang Wang, Mingcai Wu   +5 more
doaj   +1 more source

Appropriate vancomycin use in a Malaysian tertiary hospital based on current HICPAC recommendations

Journal of Infection in Developing Countries, 2014
Introduction: Antibiotic resistance is a rapidly emerging problem. A major concern is methicillin-resistant Staphylococcus aureus (MRSA), especially in developing countries where cost-effectiveness is imperative.
Farida Islahudin, Hui-Yeah Ong
doaj   +1 more source

Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. [PDF]

, 2019
Introduction:Treatment of open fractures routinely involves multiple surgeries and delayed definitive fracture fixation because of concern for infection.
Bernthal, NM, Hegde, V, Loftin, AH, Niska, J, Segura, T, Stavrakis, AI, Weixian, X, Zhu, S   +7 more
core  

Faecal microbiota transplantation : a regulatory hurdle? [PDF]

, 2017
During faecal microbiota transplantation, stool from a healthy donor is transplanted to treat a variety of dysbiosis-associated gut diseases. Competent authorities are faced with the challenge to provide adequate regulation.
De Spiegeleer, Bart, Janssens, Yorick, Verbeke, Frederick, Wynendaele, Evelien   +3 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Vancomycin-resistant Staphylococcus aureus (VRSA) can overcome the cost of antibiotic resistance and may threaten vancomycin's clinical durability.

PLoS Pathogens
Vancomycin has proven remarkably durable to resistance evolution by Staphylococcus aureus despite widespread treatment with vancomycin in the clinic. Only 16 cases of vancomycin-resistant S. aureus (VRSA) have been documented in the United States.
Samuel E Blechman, Erik S Wright
doaj   +1 more source

An Unusual Case of Ototoxicity with Use of Oral Vancomycin

Case Reports in Infectious Diseases, 2018
Introduction. Systemic absorption of oral vancomycin is poor due to the size of the molecule and its pharmacokinetics. It has an elimination half life of 5–11 hours in patients with normal renal function.
Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh   +4 more
doaj   +1 more source

Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]

, 2017
In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De, Mascellino, Maria Teresa, Oliva, Alessandra   +2 more
core   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

A Vancomycin-Arginine Conjugate Inhibits Growth of Carbapenem-resistant E. coli and Targets Cell-Wall Synthesis.

ACS Chemical Biology, 2019
The emergence of multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Enterobacteriaceae, is a major health problem that necessitates the development of new antibiotics.
Alexandra Antonoplis, Xiaoyu Zang, Tristan Wegner, P. Wender, L. Cegelski   +4 more
semanticscholar   +1 more source