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Evolution of the Variant Surface Glycoprotein Family in African Trypanosomes
An intriguing and remarkable feature of African trypanosomes is their antigenic variation system, mediated by the variant surface glycoprotein (VSG) family and fundamental to both immune evasion and disease epidemiology within host populations.
Andrew P Jackson +2 more
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African trypanosomes escape the host immune response through a periodical change of their surface coat made of one major type of protein, the variant surface glycoprotein. From a repertoire of a thousand variant surface glycoprotein genes available, only
Etienne Pays, L Vanhamme
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The Architecture of Variant Surface Glycoprotein Gene Expression Sites in Trypanosoma brucei
Molecular and Biochemical Parasitology, 2002Piet Borst, Neil Hall, Matthew Berriman
exaly
Release and Purification of Trypanosoma Brucei Variant Surface Glycoprotein
Journal of Cellular Biochemistry, 1984George A.M. Cross
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