Results 91 to 100 of about 1,681,314 (226)
Thermo-Efficient Strains of Variola Major Virus
Journal of General Virology, 1967 Thermo-efficient and thermo-sensitive mutants of pox viruses are obtained, without the aid of mutagens, only with difficulty. Kirn and his colleagues (1, 2) have described both a thermo-sensitive and a thermo-efficient mutant of vaccinia virus. This note reports the derivation and properties of two thermo-efficient strains of variola major virus.
H. S. Bedson +2 more
openaire +3 more sources
Current Progress in Targeting Human Cytomegalovirus Infection
iLABMED, Volume 3, Issue 3, Page 303-311, September 2025.This review highlights recent advances in the mechanisms by which human cytomegalovirus (HCMV) maintains its genome in infected cells, as well as the cellular factors and viral antigens that modulate viral reactivation, which reveal potential targets for addressing HCMV infection.
Yonggang Pei, Jun Chen
wiley +1 more source
4P Dermatology: A Shift to a Comprehensive Patient‐Centered Model
JEADV Clinical Practice, Volume 4, Issue S1, Page S15-S25, September 2025.ABSTRACT Advances in dermatology are embracing a patient‐centered, proactive approach through the ‘4P model’: Personalized, Predictive, Preventive, and Participatory care. This shift aims to improve treatment efficacy and safety as well as patient's quality of life. This review explores the applications of ‘4P medicine’ in dermatology, highlighting key
Brigitte Dréno +4 more
wiley +1 more source
Public Health Challenges, Volume 4, Issue 3, September 2025.This paper highlights key public health interventions and control strategies implemented during mpox outbreaks, emphasizing early detection, targeted prevention, and the role of vaccination and education in mitigating disease transmission. ABSTRACT Mpox (formerly—monkeypox) is the second viral pit break after COVID‐19.
Muhammad Shaheer Bin Faheem +6 more
wiley +1 more source
Journal of Biomolecular Structure and Dynamics, 2014 Smallpox was one of the most devastating diseases in the human history and still represents a serious menace today due to its potential use by bioterrorists.
A. P. Guimarães +2 more
semanticscholar +1 more source
Public Health Challenges, Volume 4, Issue 3, September 2025.ABSTRACT Background and Aim Mathematical modelling plays an important role in public health by enabling the prediction of disease outbreaks, assessment of transmission dynamics and evaluation of intervention strategies. Although widely applied in high‐resource settings, its use in underserved contexts remains underexplored. This review aimed to examine
Mavhunga Khumbudzo +3 more
wiley +1 more source
Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector
ZoonosesVaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
doaj +1 more source
Risk, Hazards &Crisis in Public Policy, Volume 16, Issue 3, September 2025.Abstract This study aims to identify different frontline emergency response workforce's perceived knowledge of hazards and their willingness and motivations to go to work during them. An online version of the “Fight or Flight” survey was distributed and collected from Norwegian emergency personnel during the spring of 2023.
Jarle L. Sørensen +9 more
wiley +1 more source
Bioactive Polysulfate‐Based Nano‐Assemblies Against Virus Infection
Small, Volume 21, Issue 36, September 11, 2025.Nano‐assemblies with a defined brush‐like corona are developed from sulfated polyglycerol to inhibit virus infection. The sulfate residues on the surface can actively bind the virus and entrap it from entering the host cells. This nanosystem is demonstrated potent inhibition against both HSV‐1 and SARs‐CoV‐2.
Guoxin Ma +9 more
wiley +1 more source
Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibition
RNA: A publication of the RNA Society, 2014 Diverse genetic and biochemical assays are used to conclude that the Z-DNA/RNA binding domain of the vaccinia E3L protein contributes to the interdiction of PKR activity, but that this function is not affected by mutations that disrupt Z-DNA binding.
M. Thakur, E. Seo, T. Dever
semanticscholar +1 more source