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Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector
Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
doaj +1 more source
Viral detection by electron microscopy: past, present and future. [PDF]
International audienceViruses are very small and most of them can be seen only by TEM (transmission electron microscopy). TEM has therefore made a major contribution to virology, including the discovery of many viruses, the diagnosis of various viral ...
Ait-Goughoulte+92 more
core +3 more sources
Mpox Outbreak: A Call for Urgent Action and Improved Response Strategies
ABSTRACT Introduction The resurgence of mpox presents a significant global public health challenge, especially in non‐endemic regions. Following its initial global spread in 2022, the current outbreak is driven by a newly emerged Clade I, exhibiting atypical clinical manifestations and altered transmission patterns.
Majani Edward+3 more
wiley +1 more source
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary+3 more
wiley +1 more source
In the aftermath of the September 11, 2001 attacks and the subsequent mail-borne anthrax attack of October 2001, it has become dear that health care providers may be called upon to respond to victims of terrorism. Biological terrorism (BT), in particular,
Centers for Disease Control and Prevention+4 more
core +2 more sources
Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism
In the course of evolution, viruses have developed various molecular mechanisms to evade the defense reactions of the host organism. When understanding the mechanisms used by viruses to overcome manifold defense systems of the animal organism ...
Sergei N. Shchelkunov
doaj +1 more source
Time scale evolution of avipoxviruses [PDF]
Avipoxviruses are divided into three clades: canarypox-like viruses, fowlpox-like viruses, and psittacinepox-like viruses. Several molecular clock and demographic models available in the BEAST package were compared on three avipoxvirus genes (P4b ...
Le Loc’h, Guillaume+2 more
core +1 more source
ABSTRACT Mpox, a zoonotic orthopox virus, has re‐emerged globally since May 2022. In Tokyo, 168 cases were reported in 2023. About 20% were diagnosed in our department. In this study, we analyzed the clinical and epidemiological characteristics of 32 mpox patients diagnosed in our department in 2023.
Amika Nakazawa+5 more
wiley +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Abstract Outbreaks of highly pathogenic avian influenza (HPAI) have intensified over the last decade, spotlighting the concept of “epicentre” as a means of locating disease origins. Although epicentre thinking can facilitate rapid interventions, it often overlooks the political‐economic and ecological forces driving outbreaks.
Mariel Aguilar‐Støen+4 more
wiley +1 more source