Results 91 to 100 of about 14,974 (222)

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source

Poxvirus-encoded TNF decoy receptors inhibit the biological activity of transmembrane TNF [PDF]

, 2015
© 2015 The Authors. Poxviruses encode up to four different soluble TNF receptors, named cytokine response modifier B (CrmB), CrmC, CrmD and CrmE. These proteins mimic the extracellular domain of the cellular TNF receptors to bind and inhibit the activity
Alcamí, Antonio, Alejo, Alí, Pontejo, Sergio M.   +2 more
core   +1 more source

Untersuchungen am Virus der Variola-Vaccine

Zeitschrift für Naturforschung B, 1954
Der nach Pepsinhydrolyse von Vaccine-Elementarkörpern freigelegte Innenkörper kann nach Depolymerisierung der DNS durch Desoxyribonuclease mit einer zweiten Pepsinbehandlung fast völlig abgebaut werden. Er verhält sich in dieser Hinsicht wie die Kerne von Bakterien und höheren Zellen und scheint neben DNS-Histon auch noch andere Proteine zu enthalten ...
Dietrich Peters, Walther Stoeckenius
openaire   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 636-647, March 2026.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source

Expression and functional characterisation of Variola and Monkeypox virus tumour necrosis factor receptor (TNFR) proteins [PDF]

, 2012
University of Technology, Sydney. Faculty of Science.Tumour necrosis factor-a (TNFα) is a pleiotropic cytokine that plays a critical role in cellular response to virus infection. Virtually all poxviruses encode genes that are homologous to human tumour
Sherwood, S
core  

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Introduction [PDF]

, 2017
Contains fulltext : 190586.pdf (publisher's version ) (Open Access)20 ...
Devos, Isabelle, Janssens, Angélique
core   +3 more sources

Untersuchungen am Virus der Variola-Vaccine

Zeitschrift für Naturforschung B, 1953
Erschöpfende Pepsinbehandlung an Vaccine-Elementarkörpern (Elk.), die von der Chorioallantois des bebrüteten Hühnereies bzw. von der Kaninchencornea präpariert worden waren, führte zur Erkennung unterscheidbarer Abbaustadien. Neben morphologisch intakten wurden abgebaute Elk. mit Innenkörpern stark variierender Größe und Dichte und leere Elk.-Membranen
Dietrich Peters, Theodor Nasemann
openaire   +1 more source

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

PLoS Pathogens, 2015
Orthopoxviruses (OPV), including variola, vaccinia, monkeypox, cowpox and ectromelia viruses cause acute infections in their hosts. With the exception of variola virus (VARV), the etiological agent of smallpox, other OPV have been reported to persist in ...
Isaac G Sakala, Geeta Chaudhri, Anthony A Scalzo, Preethi Eldi, Timothy P Newsome, Robert M Buller, Gunasegaran Karupiah   +6 more
doaj   +1 more source

Orthopoxvirus Genome Evolution: The Role of Gene Loss

Viruses, 2010
Poxviruses are highly successful pathogens, known to infect a variety of hosts. The family Poxviridae includes Variola virus, the causative agent of smallpox, which has been eradicated as a public health threat but could potentially reemerge as a ...
Eneida L. Hatcher, Elliot J. Lefkowitz, Robert Curtis Hendrickson, Chunlin Wang   +3 more
doaj   +1 more source