Results 11 to 20 of about 14,974 (222)

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

open access: yesPLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates   +5 more
doaj   +1 more source

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido

open access: yesInterdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa   +1 more
doaj   +1 more source

Functional epitopes and neutralizing antibodies of vaccinia virus

open access: yesFrontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng   +12 more
doaj   +1 more source

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

open access: yesmSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson   +14 more
doaj   +1 more source

Characterization of Two Historic Smallpox Specimens from a Czech Museum

open access: yesViruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer   +22 more
doaj   +1 more source

From actually toxic to highly specific – novel drugs against poxviruses [PDF]

open access: yes, 2007
The potential use of variola virus, the causative agent of smallpox, as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections. Chemotherapeutic approaches to control viral
Sliva, Katja, Schnierle, Barbara
core   +2 more sources

SUSCEPTIBILITY OF SUCKLING MICE TO VARIOLA VIRUS [PDF]

open access: yesJournal of Bacteriology, 1961
Marshall, Ronald G. (Army Chemical Corps, Fredrick, Md.), and Peter J. Gerone . Susceptibility of suckling mice to variola virus. J. Bacteriol. 82: 15–19. 1961.—The susceptibility of suckling mice inoculated intraperitoneally or intracerebrally with variola virus was investigated.
R G, MARSHALL, P J, GERONE
openaire   +2 more sources

Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans

open access: yesViruses, 2022
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj   +1 more source

Single-Dose Assay Technique for Variola Virus [PDF]

open access: yesApplied Microbiology, 1964
A biological assay for variola virus was needed that would (i) require a minimum of time and (ii) have acceptable precision. Preliminary titrations made in 11-day-old embryonated eggs and in suckling mice (6 to 24 hr of age) demonstrated a linear relationship between the concentration of variola virus injected and the mean reciprocal time to death (MTD)
J M, RILEY, M D, ORLANDO
openaire   +2 more sources

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