Results 11 to 20 of about 10,310 (196)

Use of live Variola virus to determine whether CAST/EiJ mice are a suitable surrogate animal model for human smallpox. [PDF]

Virus Res, 2020
Gallardo-Romero NF, Hutson CL, Carroll D, Kondas AV, Salzer JS, Dietz-Ostergaard S, Smith S, Hudson P, Olson V, Damon I.   +9 more
europepmc   +2 more sources

Untersuchungen am Virus der Variola-Vaccine [PDF]

Zeitschrift für Naturforschung B, 1953
Erschöpfende Pepsinbehandlung an Vaccine-Elementarkörpern (Elk.), die von der Chorioallantois des bebrüteten Hühnereies bzw. von der Kaninchencornea präpariert worden waren, führte zur Erkennung unterscheidbarer Abbaustadien. Neben morphologisch intakten wurden abgebaute Elk. mit Innenkörpern stark variierender Größe und Dichte und leere Elk.-Membranen
Dietrich Peters, Theodor Nasemann
openalex   +2 more sources

Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox: part II. [PDF]

J Biomol Struct Dyn, 2019
Rodrigues Garcia D, Rodrigues de Souza F, Paula Guimarães A, Castro Ramalho T, Palermo de Aguiar A, Celmar Costa França T.   +5 more
europepmc   +3 more sources

Immunological Memory after Exposure to Variola Virus, Monkeypox Virus, and Vaccinia Virus [PDF]

The Journal of Infectious Diseases, 2007
We compared cellular and humoral immunity to vaccinia virus (VV) in individuals exposed to 3 different orthopoxviruses: 154 individuals previously vaccinated with VV, 7 individuals with a history of monkeypox virus infection, and 8 individuals with a history of variola virus infection.
Sumathi Sivapalasingam, Jeffrey S. Kennedy, William Borkowsky, Fred Valentine, Ming‐Xia Zhan, Pamela Pazoles, A Paolino, F A Ennis, Neal H. Steigbigel   +8 more
openalex   +4 more sources

17^th Century Variola Virus Reveals the Recent History of Smallpox. [PDF]

Curr Biol, 2016
Duggan AT, Perdomo MF, Piombino-Mascali D, Marciniak S, Poinar D, Emery MV, Buchmann JP, Duchêne S, Jankauskas R, Humphreys M, Golding GB, Southon J, Devault A, Rouillard JM, Sahl JW, Dutour O, Hedman K, Sajantila A, Smith GL, Holmes EC, Poinar HN.   +20 more
europepmc   +3 more sources

EPIPOX: Immunoinformatic Characterization of the Shared T-Cell Epitome between Variola Virus and Related Pathogenic Orthopoxviruses [PDF]

Journal of Immunology Research, 2015
Concerns that variola viruses might be used as bioweapons have renewed the interest in developing new and safer smallpox vaccines. Variola virus genomes are now widely available, allowing computational characterization of the entire T-cell epitome and ...
Magdalena Molero-Abraham, John-Paul Glutting, Darren R. Flower, Esther M. Lafuente, Pedro A. Reche   +4 more
doaj   +2 more sources

Identification of SNPs associated with variola virus virulence. [PDF]

BioData Min, 2013
Abstract Background Decades after the eradication of smallpox, its etiological agent, variola virus (VARV), remains a threat as a potential bioweapon. Outbreaks of smallpox around the time of the global eradication effort exhibited variable case fatality rates (CFRs), likely attributable in part to complex viral ...
Hoen AG, Gardner SN, Moore JH.
europepmc   +4 more sources

Biological threat preparedness through vaccine development and stockpiling: challenges and strategic implications [PDF]

Frontiers in Public Health
Biological threat agents such as Bacillus anthracis, Variola virus, and botulinum toxin pose serious risk to national security and public health due to their high transmissibility, lethality, and potential for weaponization.
Jungeun Lee
doaj   +2 more sources

Variola Virus [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

Neutralization Determinants on Poxviruses

Viruses, 2023
Smallpox was a highly contagious disease caused by the variola virus. The disease affected millions of people over thousands of years and variola virus ranked as one of the deadliest viruses in human history. The complete eradication of smallpox in 1980,
Vernuccio Riccardo, Guardado-Calvo Pablo
doaj   +1 more source