Results 21 to 30 of about 10,310 (196)

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

PLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates, Victoria Olson, Scott Smith, Nishi Patel, Inger Damon, Kevin Karem   +5 more
doaj   +1 more source

A Multiplex PCR/LDR Assay for the Simultaneous Identification of Category A Infectious Pathogens: Agents of Viral Hemorrhagic Fever and Variola Virus. [PDF]

PLoS ONE, 2015
CDC designated category A infectious agents pose a major risk to national security and require special action for public health preparedness. They include viruses that cause viral hemorrhagic fever (VHF) syndrome as well as variola virus, the agent of ...
Sanchita Das, Mark S Rundell, Aashiq H Mirza, Maneesh R Pingle, Kristi Shigyo, Aura R Garrison, Jason Paragas, Scott K Smith, Victoria A Olson, Davise H Larone, Eric D Spitzer, Francis Barany, Linnie M Golightly   +12 more
doaj   +1 more source

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido

Interdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa, Juan Pablo Rojas   +1 more
doaj   +1 more source

Genome-wide comparison of cowpox viruses reveals a new clade related to Variola virus. [PDF]

PLoS One, 2013
Dabrowski PW, Radonić A, Kurth A, Nitsche A.   +3 more
europepmc   +3 more sources

Functional epitopes and neutralizing antibodies of vaccinia virus

Frontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng, Naijing Hu, Yingjun Liu, Cong Xing, Longlong Luo, Xinying Li, Jing Wang, Guojiang Chen, He Xiao, Chenghua Liu, Beifen Shen, Jiannan Feng, Chunxia Qiao   +12 more
doaj   +1 more source

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Characterization of Two Historic Smallpox Specimens from a Czech Museum

Viruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer, Jiri Dresler, Hana Kabíckova, Libor Písa, Pavel Aganov, Karel Fucik, Daniel Elleder, Tomas Hron, Vitezslav Kuzelka, Petr Velemínsky, Jana Klimentova, Alena Fucikova, Jaroslav Pejchal, Rita Hrabakova, Vladimir Benes, Tobias Rausch, Pavel Dundr, Alexander Pilin, Radomir Cabala, Martin Hubalek, Jan Stríbrny, Markus H. Antwerpen, Hermann Meyer   +22 more
doaj   +1 more source

Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans

Viruses, 2022
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj   +1 more source

Trend and hotspots of research on highly pathogenic pathogens: visual analysis based on bibliometrics and bi-clustering

Zhongguo gonggong weisheng, 2023
ObjectiveTo examine status quo and development trends of research worldwide on highly pathogenic pathogens. MethodsIn this study, highly pathogenic pathogens refered to 29 pathogens classified as pathogens of first category in the List of Human ...
Luona LI, Kunlan ZUO, Lili MA, Huan LIU
doaj   +1 more source

Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits

Molecular Therapy: Nucleic Acids, 2022
Poxviruses are a large and complex family of viruses with members such as monkeypox virus and variola virus. The possibility of an outbreak of monkeypox virus (or a related poxvirus) or the misuse of variola virus justifies the development of ...
Eric M. Mucker, Carolin Thiele-Suess, Patrick Baumhof, Jay W. Hooper   +3 more
doaj   +1 more source