Results 41 to 50 of about 1,665,482 (247)

Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]

open access: yesPLoS ONE, 2015
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates   +5 more
doaj   +1 more source

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido

open access: yesInterdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa   +1 more
doaj   +1 more source

Functional epitopes and neutralizing antibodies of vaccinia virus

open access: yesFrontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng   +12 more
doaj   +1 more source

Are we there yet? The smallpox research agenda using variola virus. [PDF]

open access: yesPLoS Pathog, 2014
Despite significant advances, there is more work to be done before the international community can be confident that it possesses sufficient protection against any future smallpox threats.
Damon IK, Damaso CR, McFadden G.
europepmc   +2 more sources

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

open access: yesmSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson   +14 more
doaj   +1 more source

Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans

open access: yesViruses, 2022
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

open access: yes, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Bartlett, Nathan W   +8 more
core   +2 more sources

Characterization of Two Historic Smallpox Specimens from a Czech Museum

open access: yesViruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer   +22 more
doaj   +1 more source

Trend and hotspots of research on highly pathogenic pathogens: visual analysis based on bibliometrics and bi-clustering

open access: yesZhongguo gonggong weisheng, 2023
ObjectiveTo examine status quo and development trends of research worldwide on highly pathogenic pathogens. MethodsIn this study, highly pathogenic pathogens refered to 29 pathogens classified as pathogens of first category in the List of Human ...
Luona LI, Kunlan ZUO, Lili MA, Huan LIU
doaj   +1 more source

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