Results 41 to 50 of about 1,665,482 (247)
Development of a High-Content Orthopoxvirus Infectivity and Neutralization Assays. [PDF]
Currently, a number of assays measure Orthopoxvirus neutralization with serum from individuals, vaccinated against smallpox. In addition to the traditional plaque reduction neutralization test (PRNT), newer higher throughput assays are based on ...
Irina Gates+5 more
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Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa+1 more
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A homolog of the variola virus B22 membrane protein contributes to ectromelia virus pathogenicity in the mouse footpad model. [PDF]
Reynolds SE+4 more
europepmc +2 more sources
Functional epitopes and neutralizing antibodies of vaccinia virus
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng+12 more
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Are we there yet? The smallpox research agenda using variola virus. [PDF]
Despite significant advances, there is more work to be done before the international community can be confident that it possesses sufficient protection against any future smallpox threats.
Damon IK, Damaso CR, McFadden G.
europepmc +2 more sources
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson+14 more
doaj +1 more source
Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj +1 more source
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Bartlett, Nathan W+8 more
core +2 more sources
Characterization of Two Historic Smallpox Specimens from a Czech Museum
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer+22 more
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ObjectiveTo examine status quo and development trends of research worldwide on highly pathogenic pathogens. MethodsIn this study, highly pathogenic pathogens refered to 29 pathogens classified as pathogens of first category in the List of Human ...
Luona LI, Kunlan ZUO, Lili MA, Huan LIU
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