Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode [PDF]
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Atkinson, John P+14 more
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The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG+6 more
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The Mpox, serious menace, or paper tiger?
One of the most horrible diseases in history, Smallpox is caused by the Variola from Poxvirus family, has caused great morbidity and mortality along the way since it was eradicated in the 20th century.
Shahram Jalilian, Mohammad-Navid Bastani
doaj +1 more source
Variola minor in coalfield areas of England and Wales, 1921–34: geographical determinants of a national smallpox epidemic that spread out of effective control [PDF]
This paper uses techniques of binary logistic regression to identify the spatial determinants of the last national epidemic of smallpox to spread in England and Wales, the variola minor epidemic of 1921–34.
Cliffe, Andrew+2 more
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Antiviral Activity of Extracts from Basidiomycetes for Orthopoxviruses
Carried out was evaluation of the effect of water extracts from basidiomycetes in Vero cell culture on variola virus, and vaccinia virus. Antiviral effect demonstrated Inonotus obliquus (Chaga), befungin and melanin from chaga,
T. V. Teplyakova+8 more
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Phylogeographical and evolutionary history of variola major virus; a question of timescales?
Aim of this study was to reconstruct the phylogeography of variola virus (VARV) in the XX century, using 47 VARV whole genome sequences available in public databases, through two different methods for ancestral character reconstruction: a frequently used
A. Bergna+6 more
semanticscholar +1 more source
Smallpox—eradicated, but a growing terror threat [PDF]
Smallpox is a disease that followed humanity for thousands of years up until 30 years ago. It was possible to eradicate, because an effective live vaccine from crossreacting vaccinia could be developed. Twenty years have passed since vaccinations stopped
Elgh, F., Tegnell, A., Wahren, B.
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What was the primary mode of smallpox transmission? Implications for biodefense [PDF]
The mode of infection transmission has profound implications for effective containment by public health interventions. The mode of smallpox transmission was never conclusively established.
Milton, Donald Kirby
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Potential Viroporin Candidates From Pathogenic Viruses Using Bacteria-Based Bioassays
Viroporins are a family of small hydrophobic proteins found in many enveloped viruses that are capable of ion transport. Building upon the ability to inhibit influenza by blocking its archetypical M2 H+ channel, as a family, viroporins may represent a ...
Prabhat Pratap Singh Tomar+3 more
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Monkeypox Pathogenesis, Transmission, Preventive Measures and Treatment Modalities [PDF]
Monkeypox is a disease transmitted through animals but can also spread from human to human. The causative agent is monkeypox virus which is a ds-DNA virus. Monkeypox virus belongs to the orthopox genus of the poxviridae family.
Vaishnavi Uttam Goradwar, Anil Agrawal
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