Results 51 to 60 of about 10,310 (196)

Thermo-Efficient Strains of Variola Major Virus

open access: yesJournal of General Virology, 1967
Thermo-efficient and thermo-sensitive mutants of pox viruses are obtained, without the aid of mutagens, only with difficulty. Kirn and his colleagues (1, 2) have described both a thermo-sensitive and a thermo-efficient mutant of vaccinia virus. This note reports the derivation and properties of two thermo-efficient strains of variola major virus.
K R, Dumbell, H S, Bedson, M, Nizamuddin
openaire   +2 more sources

An Antigenically Atypical Strain of Variola Virus

open access: yesJournal of General Virology, 1976
The Kuwait-5-67 strain of variola virus, although indistinguishable from variola virus in its other properties, behaved atypically in immuno-diffusion tests with antivaccinia serum. The precipitation line pattern produced was similar to that of cowpox virus but lacked one of the main precipitation bands given by all other strains of variola, alastrim ...
S S, Marennikova   +3 more
openaire   +2 more sources

Should Remaining Stockpiles of Smallpox Virus (Variola) Be Destroyed?

open access: yesEmerging Infectious Diseases, 2011
In 2011, the World Health Organization will recommend the fate of existing smallpox stockpiles, but circumstances have changed since the complete destruction of these cultures was first proposed.
Raymond S. Weinstein
doaj   +1 more source

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

open access: yesViruses, 2010
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics.
R. Mark Buller   +4 more
doaj   +1 more source

Smallpox in the Post-Eradication Era

open access: yesViruses, 2020
Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world.
Hermann Meyer   +2 more
doaj   +1 more source

Untersuchungen am Virus der Variola-Vaccine

open access: yesZeitschrift für Naturforschung B, 1955
Die nach Chabaud-Fixierung und Pepsinbehandlung in der Elementarkörper-Membran zurückbleibenden Desoxyribonucleoproteide des Vaccine-Virus liegen bei den am häufigsten beobachteten Formen peripher von der im intakten Elementarkörper sichtbaren zentralen Verdichtung und sind nicht mit ihr identisch.
Walther Stoeckenius, Dietrich Peters
openaire   +1 more source

Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector

open access: yesZoonoses
Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
doaj   +1 more source

Variola virus is as old as the earliest historical lines of evidence suggest [PDF]

open access: gold, 2022
Diego Forni   +4 more
openalex   +1 more source

Untersuchungen am Virus der Variola-Vaccine

open access: yesZeitschrift für Naturforschung B, 1954
Der nach Pepsinhydrolyse von Vaccine-Elementarkörpern freigelegte Innenkörper kann nach Depolymerisierung der DNS durch Desoxyribonuclease mit einer zweiten Pepsinbehandlung fast völlig abgebaut werden. Er verhält sich in dieser Hinsicht wie die Kerne von Bakterien und höheren Zellen und scheint neben DNS-Histon auch noch andere Proteine zu enthalten ...
Dietrich Peters, Walther Stoeckenius
openaire   +1 more source

Evidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve Mice.

open access: yesPLoS Pathogens, 2015
Orthopoxviruses (OPV), including variola, vaccinia, monkeypox, cowpox and ectromelia viruses cause acute infections in their hosts. With the exception of variola virus (VARV), the etiological agent of smallpox, other OPV have been reported to persist in ...
Isaac G Sakala   +6 more
doaj   +1 more source

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