Results 51 to 60 of about 1,681,314 (226)

Viruela del simio: ¿estamos frente a un riesgo de pandemia?. Historia de un viejo conocido

Interdisciplinary Journal of Epidemiology and Public Health, 2022
La viruela del simio es una zoonosis de etiología viral causada por virus de la viruela del simio o Monkeypox virus (MPXV) (por su nombre en inglés). MPXV es un virus de ADN de doble cadena de la familia Poxviridae, a la cual pertenece el virus Variola ...
Richar Jose Gomez De la Rosa, Juan Pablo Rojas   +1 more
doaj   +1 more source

Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox). [PDF]

Antimicrob Agents Chemother, 2013
Mucker EM, Goff AJ, Shamblin JD, Grosenbach DW, Damon IK, Mehal JM, Holman RC, Carroll D, Gallardo N, Olson VA, Clemmons CJ, Hudson P, Hruby DE.   +12 more
europepmc   +2 more sources

Diverse variola virus (smallpox) strains were widespread in northern Europe in the Viking Age

Science, 2020
Viking smallpox diversity Humans have a notable capacity to withstand the ravages of infectious diseases. Smallpox killed millions of people but drove Jenner's invention of vaccination, which eventually led to the annihilation of this virus, declared in ...
Barbara Mühlemann, L. Vinner, A. Margaryan, H. Wilhelmson, Constanza de la Fuente Castro, M. Allentoft, Peter de Barros Damgaard, A. Hansen, S. Holtsmark Nielsen, L. Strand, Jan Bill, A. Buzhilova, T. Pushkina, Ceri Falys, V. Khartanovich, V. Moiseyev, M. Jørkov, Palle Østergaard Sørensen, Yvonne Magnusson, Ingrid Gustin, H. Schroeder, G. Sutter, Geoffrey L. Smith, C. Drosten, R. Fouchier, Derek J. Smith, E. Willerslev, T. Jones, M. Sikora   +28 more
semanticscholar   +1 more source

Functional epitopes and neutralizing antibodies of vaccinia virus

Frontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng, Naijing Hu, Yingjun Liu, Cong Xing, Longlong Luo, Xinying Li, Jing Wang, Guojiang Chen, He Xiao, Chenghua Liu, Beifen Shen, Jiannan Feng, Chunxia Qiao   +12 more
doaj   +1 more source

Characterization of Two Historic Smallpox Specimens from a Czech Museum

Viruses, 2017
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free.
Petr Pajer, Jiri Dresler, Hana Kabíckova, Libor Písa, Pavel Aganov, Karel Fucik, Daniel Elleder, Tomas Hron, Vitezslav Kuzelka, Petr Velemínsky, Jana Klimentova, Alena Fucikova, Jaroslav Pejchal, Rita Hrabakova, Vladimir Benes, Tobias Rausch, Pavel Dundr, Alexander Pilin, Radomir Cabala, Martin Hubalek, Jan Stríbrny, Markus H. Antwerpen, Hermann Meyer   +22 more
doaj   +1 more source

Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model

mSphere, 2021
Preparedness activities against highly transmissible viruses with high mortality rates have been highlighted during the ongoing coronavirus disease 2019 (COVID-19) pandemic.
Christina L. Hutson, Ashley V. Kondas, Mathew R. Mauldin, Jeffrey B. Doty, Irma M. Grossi, Clint N. Morgan, Sharon Dietz Ostergaard, Christine M. Hughes, Yoshinori Nakazawa, Chantal Kling, Brock E. Martin, James A. Ellison, Darin D. Carroll, Nadia F. Gallardo-Romero, Victoria A. Olson   +14 more
doaj   +1 more source

Monkeypox Goes North: Ongoing Worldwide Monkeypox Infections in Humans

Viruses, 2022
In the late 1970s, global vaccination programs resulted in the eradication of smallpox. The Monkeypox virus (MPXV), which is closely related to the smallpox-inducing variola virus, was previously endemic only in Sub-Saharan Africa but is currently ...
Barbara S. Schnierle
doaj   +1 more source

Trend and hotspots of research on highly pathogenic pathogens: visual analysis based on bibliometrics and bi-clustering

Zhongguo gonggong weisheng, 2023
ObjectiveTo examine status quo and development trends of research worldwide on highly pathogenic pathogens. MethodsIn this study, highly pathogenic pathogens refered to 29 pathogens classified as pathogens of first category in the List of Human ...
Luona LI, Kunlan ZUO, Lili MA, Huan LIU
doaj   +1 more source

Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits

Molecular Therapy: Nucleic Acids, 2022
Poxviruses are a large and complex family of viruses with members such as monkeypox virus and variola virus. The possibility of an outbreak of monkeypox virus (or a related poxvirus) or the misuse of variola virus justifies the development of ...
Eric M. Mucker, Carolin Thiele-Suess, Patrick Baumhof, Jay W. Hooper   +3 more
doaj   +1 more source

Use of the Aerosol Rabbitpox Virus Model for Evaluation of Anti-Poxvirus Agents

Viruses, 2010
Smallpox is an acute disease caused by infection with variola virus that has had historic effects on the human population due to its virulence and infectivity.
Thomas G. Voss, Chad J. Roy
doaj   +1 more source