Results 71 to 80 of about 1,468,943 (359)
Sinomenine attenuates uremia vascular calcification by miR-143-5p
Scientific ReportsVascular calcification is considered to be a killer of the cardiovascular system, involved inflammation and immunity. There is no approved therapeutic strategy for the prevention of vascular calcification.
Fengyi Yu +10 more
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Vascular Calcification: Current Genetics Underlying This Complex Phenomenon
Chinese Medical Journal, 2017 Objective: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosclerotic calcification) or tunica media (
Nonanzit Pérez-Hernández +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2022 ObjectiveTo explore the relationship between serum levels of miR-129 and miR-205 and vascular calcification in non-dialysis patients with chronic kidney disease （CKD）.MethodsFrom June 2020 to January 2021，54 CKD inpatients were selected as research ...
He Lei +7 more
doaj
Cell Death and Disease, 2020 Pyruvate dehydrogenase kinase 4 (PDK4) is an important mitochondrial matrix enzyme in cellular energy regulation. Previous studies suggested that PDK4 is increased in the calcified vessels of patients with atherosclerosis and is closely associated with ...
W. Ma +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Genetics of Vascular Calcification [PDF]
Circulation Research, 2011 ### NT5E Mutations and Arterial Calcifications Hilaire et al NEJM. 2011;364:432–442. Recessive mutations in the NTE5 gene were recently described in lower-extremity vascular calcification. ENPP1 mutations were previously described in a severe disorder of vascular calcification in infancy.
openaire +2 more sources
Loss of SIRT1 in diabetes accelerates DNA damage-induced vascular calcification
Cardiovascular Research, 2020 Aims Vascular calcification is a recognized predictor of cardiovascular risk in the diabetic patient, with DNA damage and accelerated senescence linked to oxidative stress-associated pathological calcification. Having previously shown that systemic SIRT1
F. Bartoli-Leonard +5 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu +5 more
wiley +1 more source
Relationship between vascular calcification, osteoporosis and systemic inflammation
Сибирский научный медицинский журналA lot of patients with coronary heart disease often suffer from vascular calcification. In many cases it is accompanied by harmful cardiovascular events.
K. A. Nichiporuk +4 more
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