Results 71 to 80 of about 1,499,832 (396)

The Inhibitory Roles of Vitamin K in Progression of Vascular Calcification

open access: yesNutrients, 2020
Vitamin K is a fat-soluble vitamin that is indispensable for the activation of vitamin K-dependent proteins (VKDPs) and may be implicated in cardiovascular disease (CVD). Vascular calcification is intimately associated with CV events and mortality and is
A. Shioi, T. Morioka, T. Shoji, M. Emoto
semanticscholar   +1 more source

Impact of vascular calcification on cardiovascular mortality in hemodialysis patients: clinical significance, mechanisms and possible strategies for treatment

open access: yesRenal Replacement Therapy, 2017
Vascular calcification has now been recognized as a major problem in dialysis patients because of its strong influence on the prognosis. Along with the regulatory failure of calcification-inhibitory system, active phenotypic change of vascular smooth ...
Takayasu Ohtake, Shuzo Kobayashi
doaj   +1 more source

Lessons learnt from progressive vascular calcification in a renal transplant recipient

open access: yesIndian Journal of Transplantation, 2022
Chronic kidney disease − mineral bone disorder is a common complication in patients with renal failure. Vascular calcification is the part of this clinical syndrome and progresses over the years.
Urmila Anandh, Ritesh Kumar, G Ramesh
doaj   +1 more source

Is there a role for thoracic aortic calcium to fine-tune cardiovascular risk prediction? [PDF]

open access: yes, 2012
Screening asymptomatic subjects to streamline measures for the prevention of cardiovascular events remains a major challenge. The established primary prevention risk-scoring methods use equations derived from large prospective cohort studies, but further
Birgelen, C. von, Hartmann, M.
core   +3 more sources

Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease

open access: yesScientific Reports, 2020
Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC.
Armand M G Jaminon   +9 more
semanticscholar   +1 more source

The leading edge of vascular calcification [PDF]

open access: yesTrends in Cardiovascular Medicine, 2015
About two decades ago, when lipids were the focus of atherosclerosis research, calcific vasculopathy (or, more commonly, “vascular calcification”) had been dismissed as a non-biological, unregulated, degenerative phenomenon. Ironically, decades earlier, atherosclerosis itself had been dismissed in the same manner.
Demer, Linda L, Tintut, Yin
openaire   +6 more sources

The role of sacubitril/valsartan in abnormal renal function patients combined with heart failure: a meta-analysis and systematic analysis

open access: yesRenal Failure
Aims This study aimed to investigate the efficacy and safety of sacubitril/valsartan in abnormal renal function (eGFR < 60 ml/min/1.73m2) patients combined with heart failure based on randomized controlled trials (RCTs) and observational studies.Methods ...
Xinyue Yang   +4 more
doaj   +1 more source

Vascular Calcification Mechanisms [PDF]

open access: yesJournal of the American Society of Nephrology, 2004
Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of ...
openaire   +2 more sources

Relationship between effective blood flow rate and clinical outcomes in maintenance hemodialysis patients: a single-center study

open access: yesRenal Failure
The association between blood flow rate (BFR) and clinical outcomes in patients undergoing maintenance hemodialysis (MHD) is inconclusive. This retrospective study included 175 patients undergoing MHD treatment between July 2015 and March 2022, divided ...
Zhoucang Zhang   +5 more
doaj   +1 more source

Liver kinase B1 inhibits smooth muscle calcification via high mobility group box 1

open access: yesRedox Biology, 2021
Vascular calcification is a common pathological feature of atherosclerosis, chronic kidney disease, vascular injury, and aging. Liver kinase B1 (LKB1) plays pivotal roles in cellular processes such as apoptosis, metabolism, and cell cycle regulation.
Tianran Zhang   +10 more
doaj   +1 more source

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