Results 1 to 10 of about 950,338 (392)

Dynamic soluble changes in sVEGFR1, HGF, and VEGF promote chemotherapy and bevacizumab resistance: A prospective translational study in the BECOX (GEMCAD 09-01) trial [PDF]

open access: yesTumor Biology, 2017
Despite initial responsiveness, acquired resistance to both bevacizumab and chemotherapy in metastatic colorectal cancer is universal. We have recently published that in vitro, chronically oxaliplatin resistance upregulates soluble vascular endothelial ...
Estela Pineda   +19 more
doaj   +3 more sources

The Biology of Vascular Endothelial Growth Factor [PDF]

open access: yesEndocrine Reviews, 1997
The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1. Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders.
N, Ferrara, T, Davis-Smyth
openaire   +3 more sources

Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham   +3 more
doaj   +1 more source

Biology of vascular endothelial growth factors [PDF]

open access: yesFEBS Letters, 2006
Angiogenesis is the process by which new blood vessels are formed from existing vessels. The vascular endothelial growth factors (VEGFs) are considered as key molecules in the process of angiogenesis. The VEGF family currently includes VEGF‐A, ‐B, ‐C, ‐D, ‐E, ‐F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally ...
Roy, Himadri   +2 more
openaire   +2 more sources

The biology of vascular endothelial growth factors [PDF]

open access: yesCardiovascular Research, 2005
The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has provided tools for studying the vascular system in development as well as in diseases ranging from ischemic heart disease to cancer.
Tuomas, Tammela   +3 more
openaire   +2 more sources

Hypertensive cerebral hemorrhage with undetectable plasma vascular endothelial growth factor levels in a patient receiving intravitreal injection of aflibercept for bilateral diabetic macular edema: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Intravitreal injections of anti-vascular endothelial growth factor are commonly used to treat macular diseases, including diabetic macular edema.
Miwako Yoshimoto   +3 more
doaj   +1 more source

Clinical-functional and molecular characteristics of comorbid pathology (vibration disease combined with arterial hypertension)

open access: yesАтеросклероз, 2022
Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko   +4 more
doaj   +1 more source

Vascular Endothelial Growth Factor [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 1993
Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
openaire   +4 more sources

Streptozotocin induced diabetic retinopathy in rat and the expression of vascular endothelial growth factor and its receptor [PDF]

open access: yesInternational Journal of Ophthalmology, 2013
AIM:To establish the rat model of streptozotocin (STZ)-induced diabetic retinopathy (DR), which is the most common cause of visual loss and blindness in patients with diabetes, and observe the gene expression of vascular endothelial growth factor (VEGF ...
Chen-Yuan Gong   +3 more
doaj   +1 more source

Enhanced Vascularization of Cultured Skin Substitutes Genetically Modified to Overexpress Vascular Endothelial Growth Factor11The authors declared in writing to have no conflict of interest. [PDF]

open access: yes, 2000
Cultured skin substitutes have been used as adjunctive therapies in the treatment of burns and chronic wounds, but they are limited by lack of a vascular plexus.
Supp, Dorothy M.   +3 more
core   +3 more sources

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