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Biology of vascular endothelial growth factors [PDF]
FEBS Letters, 2006 Angiogenesis is the process by which new blood vessels are formed from existing vessels. The vascular endothelial growth factors (VEGFs) are considered as key molecules in the process of angiogenesis. The VEGF family currently includes VEGF‐A, ‐B, ‐C, ‐D, ‐E, ‐F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally ...
Seppo Ylä-Herttuala +2 more
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Encapsulated VEGF121-PLA microparticles promote angiogenesis in human endometrium stromal cells
Journal of Genetic Engineering and Biotechnology, 2021 Background In this study, Vascular Endothelial Growth Factor 121 expressed abundantly in endometrial stromal cells is encapsulated with poly-l-lactide and characterized the properties for endometrial angiogenesis.
Sunil Abraham +3 more
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Journal of Medical Case Reports, 2021 Background Intravitreal injections of anti-vascular endothelial growth factor are commonly used to treat macular diseases, including diabetic macular edema.
Miwako Yoshimoto +3 more
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Атеросклероз, 2022 Purpose of the study. Based on the assessment of endothelial and hemostasiological parameters, to study the possibilities of early diagnosis of vascular disorders in case of vibration disease in combination with arterial hypertension.
Oksana N. Gerasimenko +4 more
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Vascular Endothelial Growth Factor [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 1993 Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration.
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The biology of vascular endothelial growth factors [PDF]
Cardiovascular Research, 2005 The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has provided tools for studying the vascular system in development as well as in diseases ranging from ischemic heart disease to cancer.
Tuomas Tammela +3 more
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Streptozotocin induced diabetic retinopathy in rat and the expression of vascular endothelial growth factor and its receptor [PDF]
International Journal of Ophthalmology, 2013 AIM:To establish the rat model of streptozotocin (STZ)-induced diabetic retinopathy (DR), which is the most common cause of visual loss and blindness in patients with diabetes, and observe the gene expression of vascular endothelial growth factor (VEGF ...
Chen-Yuan Gong +3 more
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Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
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The Biology of Vascular Endothelial Growth Factor [PDF]
Endocrine Reviews, 1997 The establishment of a vascular supply is required for organ development and differentiation as well as for tissue repair and reproductive functions in the adult1. Neovascularization (angiogenesis) is also implicated in the pathogenesis of a number of disorders.
Napoleone Ferrara +1 more
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Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats
Clinics, 2011 INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei +5 more
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