Vascular endothelial growth factor pathway
Michael L. Maitlanda, Xing Jian Louc, Jacqueline Ramireza, Apurva A. Desaia, Dorit S. Berlinc, Howard L. McLeodb, Ralph R. Weichselbauma, Mark J. Rataina, Russ B. Altmanc, and Teri E. Kleinc aDepartment of Medicine, Section of Hematology/Oncology, University of Chicago, Maryland Avenue, Chicago, Illinois bUNC Institute for Pharmacogenomics and ...
Michael L, Maitland +9 more
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Vascular endothelial growth factor signaling in development and disease
Vascular endothelial growth factors (VEGFs) are best known for their involvement in orchestrating the development and maintenance of the blood and lymphatic vascular systems.
Sinem Karaman, V. Leppänen, K. Alitalo
semanticscholar +1 more source
Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin [PDF]
© 2016 Taylor & Francis. Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell recruitment, and eventually pulmonary fibrosis.
Crooks, Michael G. +4 more
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The function of vascular endothelial growth factor
AbstractVascular endothelial growth factor (VEGF) is considered the master regulator of angiogenesis during growth and development, as well as in disease states such as cancer, diabetes, and macular degeneration. This review details our current understanding of VEGF signaling and discusses the benefits and unexpected side effects of promising anti ...
Bonnie J, Nieves +2 more
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
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Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis
Background We recently discovered a small endogenous peptide, peptide Lv, with the ability to activate vascular endothelial growth factor receptor 2 and its downstream signaling.
Liheng Shi +12 more
doaj +1 more source
Hypoxia-induced reactive oxygen species cause chromosomal abnormalities in endothelial cells in the tumor microenvironment. [PDF]
There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability ...
Miyako Kondoh +8 more
doaj +1 more source
Trophic and neurotrophic factors in human pituitary adenomas (Review) [PDF]
The pituitary gland is an organ that functionally connects the hypothalamus with the peripheral organs. The pituitary gland is an important regulator of body homeostasis during development, stress, and other processes.
Agostinelli, Enzo +11 more
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Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul +6 more
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Vascular Endothelial Growth Factor Concentration in Brain of Rat Treated with Anaerobic Exercises [PDF]
Anaerobic exercise is a high-intensity exercise that needs quick energy supplies obtained in a very short time. However, this exercise may result in tissue hypoxia which is characterized by the increase of HIF-1α concentration.
Ardi, Y. (Yuliana) +7 more
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