Results 21 to 30 of about 765,451 (393)

Anti-inflammatory and immunomodulatory effects of rosuvastatin in patients with low-to-moderate cardiovascular risk

Acta Pharmaceutica, 2022
Statins have shown anti-inflammatory pleiotropic effects in subjects with/at risk of cardiovascular disease. The aim of this study was to evaluate the inflammatory/immunomodulatory properties of rosuvastatin in subjects at low-to-moderate cardiovascular ...
VAVLUKIS ANA, VAVLUKIS MARIJA, DIMOVSKI ALEKSANDAR, PETRUSHEVSKA GORDANA, EFTIMOV ALEKSANDAR, DOMAZETOVSKA SASHKA, MLADENOVSKA KRISTINA   +6 more
doaj   +1 more source

Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells [PDF]

Angiogenesis, 2013
Radiation therapy after lymph node dissection increases the risk of developing painful and incurable lymphedema in breast cancer patients. Lymphedema occurs when lymphatic vessels become unable to maintain proper fluid balance. The sensitivity of lymphatic endothelial cells (LECs) to ionizing radiation has not been reported to date.
Cristina T, Kesler, Angera H, Kuo, Hon-Kit, Wong, David J, Masuck, Jennifer L, Shah, Kevin R, Kozak, Kathryn D, Held, Timothy P, Padera   +7 more
openaire   +2 more sources

The vascular endothelial growth factor +405G>C polymorphism in endometriosis [PDF]

Human Reproduction, 2007
Vascular endothelial growth factor (VEGF) is a potent stimulus of angiogenesis potentially contributing to the pathogenesis of endometriosis. The aim of this study was to investigate the potential association between the single nucleotide polymorphism +405G>C of the VEGF gene with the risk of endometriosis, for the first time in the Caucasian ...
D. Gentilini, E. Somigliana, P. Viganò, M. Vignali, M. Busacca, A. M. Di Blasio   +5 more
openaire   +3 more sources

Semaphorin 3F Serves as a Tumor Suppressor in Esophageal Squamous Cell Carcinoma and is Associated With Lymph Node Metastasis in Disease Progression

Technology in Cancer Research & Treatment, 2020
Background: Esophageal squamous cell carcinoma is one of the leading aggressive malignancies with high mortality. Semaphorin 3F has been reported to be involved in lymphangiogenesis by interacting the vascular endothelial growth factor C/neuropilin 2 ...
Zhen Xie MD, Tianyue Li MD, Bingtao Huang MM, Shuai Liu MM, Lianguo Zhang MM, Qingguang Zhang MD   +5 more
doaj   +1 more source

Expression of Hypoxia-inducible factor 1-α and Vascular endothelial growth factor-C in locally advanced breast cancer patients

Clinics, 2011
BACKGROUND: Locally advanced breast cancers are more prevalent in underdeveloped countries. Targeted therapy has been improved to identify hallmarks that are specific to these subtypes of tumors.
Luiz Gustavo Oliveira Brito, Viviane Fernandes Schiavon, Jurandyr Moreira de Andrade, Daniel Guimarães Tiezzi, Fernanda Maris Peria, Heitor Ricardo Cosiski Marana   +5 more
doaj   +1 more source

Cystatin C Expression is Promoted by VEGFA Blocking, With Inhibitory Effects on Endothelial Cell Angiogenic Functions Including Proliferation, Migration, and Chorioallantoic Membrane Angiogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Vascular development, including vasculogenesis and angiogenesis, is involved in many diseases. Cystatin C (CST3) is a commonly used marker of renal dysfunction, and we have previously reported that its expression level is associated with ...
Zhenkun Li, Shiyuan Wang, Xueyun Huo, Hefen Yu, Jing Lu, Shuangyue Zhang, Xiaohong Li, Qi Cao, Changlong Li, Meng Guo, Jianyi Lv, Xiaoyan Du, Zhenwen Chen   +12 more
doaj   +1 more source

Expression levels of vascular endothelial growth factors A and C in patients with peptic ulcers and gastric cancer [PDF]

, 2014
Purpose: Vascular endothelial growth factor (VEGF) is one of the most important growth factors for metastatic tumors. To clarify the role of VEGF-A and C in patients with peptic ulcer disease (PUD) or gastric cancer (GC), we evaluated the expression ...
Abbasi, A., Ajami, A., Ajami, M., Farazmandfar, T., Hafezi, N., Hosseini, V., Mohammadian, R., Sankian, M., Taghizadeh, S., Tehrani, M.   +9 more
core   +2 more sources

Vascular endothelial growth factor C induces angiogenesis in vivo [PDF]

Proceedings of the National Academy of Sciences, 1998
Vascular endothelial growth factor C (VEGF-C) recently has been described to be a relatively specific growth factor for the lymphatic vascular system. Here we report that ectopic application of recombinant VEGF-C also has potent angiogenic effects in vivo .
Y, Cao, P, Linden, J, Farnebo, R, Cao, A, Eriksson, V, Kumar, J H, Qi, L, Claesson-Welsh, K, Alitalo   +8 more
openaire   +2 more sources

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis [PDF]

The EMBO Journal, 2001
Metastasis is a frequent and lethal complication of cancer. Vascular endothelial growth factor-C (VEGF-C) is a recently described lymphangiogenic factor. Increased expression of VEGF-C in primary tumours correlates with dissemination of tumour cells to regional lymph nodes.
Mandriota, Stefano Jacopo, Jussila, Lotta, Jeltsch, Michael, Compagni, Amelia, Baetens Baumann, Danielle, Prevo, Remko, Banerji, Suneale, Huarte, Joachim, Montesano, Roberto, Jackson, David G., Orci, Lelio, Alitalo, Kari, Christofori, Gerhard, Pepper, Michael Sean   +13 more
openaire   +3 more sources

Clinicopathological impact of VEGFR2 and VEGF‐C in patients with EGFR‐major mutant NSCLC receiving osimertinib

Thoracic Cancer, 2023
Background Vascular endothelial growth factor (VEGF) has been identified as one of the resistant mechanisms to epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs).
Kyoichi Kaira, Hisao Imai, Atsuto Mouri, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Kunihiko Kobayashi, Tomonori Kawasaki, Masanori Yasuda, Hiroshi Kagamu   +10 more
doaj   +1 more source