Results 211 to 220 of about 200,188 (263)

Vascular endothelium in atherosclerosis

Cell and Tissue Research, 2008
Their strategic location between blood and tissue and their constitutive properties allow endothelial cells (EC) to monitor the transport of plasma molecules, by employing bidirectional receptor-mediated and receptor-independent transcytosis and endocytosis, and to regulate vascular tone, cellular cholesterol and lipid homeostasis. These cells are also
Anca V, Sima, Camelia S, Stancu, Maya, Simionescu   +2 more
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ION CHANNELS IN VASCULAR ENDOTHELIUM

Annual Review of Physiology, 1997
▪ Abstract  The functional impact of ion channels in vascular endothelial cells (ECs) is still a matter of controversy. This review describes different types of ion channels in ECs and their role in electrogenesis, Ca2+ signaling, vessel permeability, cell-cell communication, mechano-sensor functions, and pH and volume regulation.
Nilius, Bernd, Viana, Félix, Droogmans, Guy   +2 more
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Vascular Endothelium and Atherosclerosis

2006
Atherosclerosis depends critically on altered behavior of the intrinsic cells of the artery wall, the endothelial cells and smooth muscle cells, and inflammatory leukocytes that join them in the arterial intima during the atherogenic process. The homeostatic properties of the normal endothelium contribute importantly to maintenance of aspects of ...
P, Libby, M, Aikawa, M K, Jain
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Estrogens and the Vascular Endothelium

Annals of the New York Academy of Sciences, 2002
Abstract: Estrogens exert important regulatory functions on vessel wall components, which may contribute to the increased prevalence and severity of certain chronic inflammatory and autoimmune diseases in females and the lower cardiovascular risk observed in premenopausal women. Endothelial cells have been recently identified as targets for estrogens,
Maria C, Cid, H William, Schnaper, Hynda K, Kleinman   +2 more
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Vascular endothelium in cancer

Cell and Tissue Research, 2008
The vascular endothelium plays an essential role during organogenesis and in tissue homeostasis. Growing evidence also supports its essential and complex role in tumour biology and cancer progression. In particular, excessive proliferation and transformation or dysfunction of endothelial cells leads to pathological (lymph)angiogenesis or vascular ...
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Tumor Interaction with Vascular Endothelium

Pathophysiology of Haemostasis and Thrombosis, 1987
Clinical and experimental observations suggest that tumor-induced endothelial cell (EC) injury may be one of several initial events in the establishment of tumor metastases. This work investigates tumor-induced EC injury and the interaction between tumor-damaged EC and platelets.
H, Al-Mondhiry, V, McGarvey
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Vascular Endothelium and Ca2† Antagonists

Journal of Cardiovascular Pharmacology, 1988
Endothelial cells can release both relaxing and contracting factors. Since the release of endothelium-dependent relaxing factor is prevented by incubation in Ca2+-free solution and can be triggered by the Ca2+ ionophore A 23187, it must require an increase in cytoplasmic Ca2+ concentration in the endothelial cells.
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Epigenetics of the vascular endothelium

Journal of Applied Physiology, 2010
Classical models of transcription in vascular endothelial cells, specifically the cis/trans paradigm, have limitations. For instance, how does the environment have chronic effects on gene expression in endothelial cells after weeks or years? When an endothelial cell divides, how is this information transmitted to daughter cells?
Matthew Shu-Ching, Yan, Charles C, Matouk, Philip A, Marsden   +2 more
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Vascular Endothelium and Blood Flow

2006
Major advances have been made over the last decade towards the elucidation of the molecular mechanisms involved in the endothelium-dependent regulation of vascular tone and blood flow. While the primary endothelium-derived vasodilator autacoid is nitric oxide, it is clear that epoxyeicosatrienoic acids and other endothelium-derived hyperpolarising ...
R, Busse, I, Fleming
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Hemodynamics and the Vascular Endothelium

Journal of Biomechanical Engineering, 1993
The endothelium, once thought to be a passive, non-thrombogenic barrier, is now recognized as being a dynamic participant in vascular biology and pathobiology. Part of its dynamic nature is due to the influence of the mechanical environment imposed by the hemodynamics of the vascular system.
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