Results 11 to 20 of about 385,157 (356)
Regulation of vascular smooth muscle cell differentiation [PDF]
Journal of Vascular Surgery, 2007 Vascular smooth muscle cell (VSMC) differentiation is an essential component of vascular development. These cells perform biosynthetic, proliferative, and contractile roles in the vessel wall. VSMCs are not terminally differentiated and are able to modulate their phenotype in response to changing local environmental cues.
Kathleen A. Martin +2 more
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The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension [PDF]
Journal of Experimental Pharmacology, 2012 Richard E RobertsSchool of Biomedical Sciences, University of Nottingham, Nottingham, United KingdomAbstract: Hypertension is a risk factor for myocardial infarction, stroke, renal failure, heart failure, and peripheral vascular disease.
Roberts RE
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Specialized mouse embryonic stem cells for studying vascular development [PDF]
Stem Cells and Cloning: Advances and Applications, 2014 Drew E Glaser,1 Andrew B Burns,2 Rachel Hatano,2 Magdalena Medrzycki,3 Yuhong Fan,3 Kara E McCloskey1 1School of Engineering, University of California, Merced, CA, USA; 2School of Natural Sciences, University of California, Merced, CA, USA; 3School of ...
Glaser DE +5 more
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Lack of α8 integrin leads to morphological changes in renal mesangial cells, but not in vascular smooth muscle cells [PDF]
BMC Cell Biology, 2010 Background Extracellular matrix receptors of the integrin family are known to regulate cell adhesion, shape and functions. The α8 integrin chain is expressed in glomerular mesangial cells and in vascular smooth muscle cells.
Hilgers Karl F +9 more
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Vascular Smooth Muscle Cell [PDF]
, 2018 Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall and are responsible for regulating arterial tone, blood pressure, and blood supply of the tissues.
Ning Zhou +3 more
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The role of p53 in the alternation of vascular functions
Frontiers in Pharmacology, 2022 Ageing is a risk factor for many degenerative diseases. Cardiovascular diseases (CVDs) are usually big burdens for elderly, caregivers and the health system.
Gabriel Hoi-Huen Chan +7 more
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Smooth Muscle Cells for Vascular Engineering [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011 In the first decade of this century, ever-increasing scientific and technological advances are revolutionizing our approaches to developing therapies that bring about the promise of personalized medicine and the possibility of regenerative interventions.
Y. Eugene Chen +2 more
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Metabolism of vascular smooth muscle cells in vascular diseases [PDF]
American Journal of Physiology-Heart and Circulatory Physiology, 2020 Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer of arteries and are essential for arterial physiology and pathology. It is becoming increasingly clear that VSMCs can alter their metabolism to fulfill the bioenergetic and biosynthetic requirements. During vascular injury, VSMCs switch from a quiescent “contractile”
Jia Shi +4 more
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Vascular Smooth Muscle Cells in Atherosclerosis [PDF]
Circulation Research, 2016 The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced plaques are entirely beneficial, for example preventing rupture of the fibrous cap.
Gary K. Owens +2 more
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Journal of Extracellular Vesicles, 2020 The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer +7 more
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