Results 1 to 10 of about 230,978 (150)
EPAC in Vascular Smooth Muscle Cells [PDF]
International Journal of Molecular Sciences, 2020 Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process known as phenotypic switching. During this process, VSMCs lose their contractility and acquire a synthetic phenotype, where they over ...
Nadine Wehbe +9 more
openaire +3 more sources
Role of smooth muscle progenitor cells in vascular mechanical injury and repair
Medicine in Novel Technology and Devices, 2022 Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong +7 more
doaj +1 more source
Long non-coding RNAs: Modulators of phenotypic transformation in vascular smooth muscle cells
Frontiers in Cardiovascular Medicine, 2022 Long non-coding RNA (lncRNAs) are longer than 200 nucleotides and cannot encode proteins but can regulate the expression of genes through epigenetic, transcriptional, and post-transcriptional modifications.
Bing-Han Lu +16 more
doaj +1 more source
Transcription factor GATA6 promotes migration of human coronary artery smooth muscle cells in vitro
Frontiers in Physiology, 2022 Vascular smooth muscle cell plasticity plays a pivotal role in the pathophysiology of vascular diseases. Despite compelling evidence demonstrating the importance of transcription factor GATA6 in vascular smooth muscle, the functional role of GATA6 ...
Azra Alajbegovic +6 more
doaj +1 more source
Smoothelin in Vascular Smooth Muscle Cells [PDF]
Trends in Cardiovascular Medicine, 2007 Smoothelin-A and -B have only been found in fully differentiated contractile smooth muscle cells. They are increasingly used to monitor the smooth muscle cell differentiation process to a contractile or synthetic phenotype. Vascular-specific smoothelin-B is the first smooth muscle cell marker that disappears when vascular tissues are compromised, for ...
van Eys, G.J.J.M. +2 more
openaire +3 more sources
Vinpocetine Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells. [PDF]
PLoS ONE, 2016 Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown.
Yun-Yun Ma +8 more
doaj +1 more source
Cells, 2021 Among reactive oxygen species, superoxide mediates the critical vascular redox signaling, resulting in the regulation of the human cardiovascular system.
Kazumi Takaishi +3 more
doaj +1 more source
Smooth muscle cells and vascular diseases [PDF]
Cardiovascular Research, 2012 Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, and, due to their myosin/actin interactions, they are also responsible for arterial contractile tonus and regulating blood pressure and flow in relation to specific metabolic demands.
Jean-Baptiste, Michel +2 more
openaire +2 more sources
Vascular smooth muscle cells in atherosclerosis [PDF]
Nature Reviews Cardiology, 2019 Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an atherosclerotic plaque. According to the 'response to injury' and 'vulnerable plaque' hypotheses, contractile VSMCs recruited from the media undergo phenotypic conversion to proliferative synthetic cells that generate extracellular matrix to form the fibrous cap and ...
Basatemur, Gemma L +4 more
openaire +3 more sources
Smooth Muscle Cells for Vascular Engineering [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011 In the first decade of this century, ever-increasing scientific and technological advances are revolutionizing our approaches to developing therapies that bring about the promise of personalized medicine and the possibility of regenerative interventions.
Y Eugene, Chen +2 more
openaire +2 more sources