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Vascular Smooth Muscle Cells in Atherosclerosis. [PDF]
Circulation Research, 2016 The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced plaques are entirely beneficial, for example preventing rupture of the fibrous ...
M. Bennett, S. Sinha, G. Owens
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Vascular smooth muscle cells in atherosclerosis [PDF]
Nature Reviews Cardiology, 2019 Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an atherosclerotic plaque. According to the 'response to injury' and 'vulnerable plaque' hypotheses, contractile VSMCs recruited from the media undergo phenotypic conversion to proliferative synthetic cells that generate extracellular matrix to form the fibrous cap and ...
Gemma Basatemur +4 more
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Metabolism of vascular smooth muscle cells in vascular diseases. [PDF]
American Journal of Physiology-Heart and Circulatory Physiology, 2020 Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer of arteries and are essential for arterial physiology and pathology.
Jia Shi +4 more
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Vascular Smooth Muscle Cells. [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016 Decades of work have shown that vascular smooth muscle cell (SMC) phenotypes are controlled by cues received from the local environment.1–3 When nestled into a cage of cross-linked collagen and elastin of its own making,4 medial SMCs exhibit a fully ...
M. Majesky
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Smooth Muscle Cells in Vascular Remodeling. [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2019 As the primary causes of myocardial infarction, stroke, atherosclerosis, in-stent restenosis, and aneurysm, aortic diseases pose a serious threat to human health.
Ning Shi, Xiaohan Mei, Shi-You Chen
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Origin and differentiation of vascular smooth muscle cells [PDF]
The Journal of Physiology, 2015 Vascular smooth muscle cells (SMCs), a major structural component of the vessel wall, not only play a key role in maintaining vascular structure but also perform various functions.
Gang Wang +3 more
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Regulation of the cell magnesium in vascular smooth muscle
The Journal of Physiology, 1974 1. The relation between [Mg]o and the Mg content of the rat tail artery incubated in Ca‐free solutions was studied.2. Variation of [Mg]o in Ca‐free Krebs solution between 0·6 and 2·4 m m did not affect the cell Mg. In ATP‐depleted arteries, a sizeable fraction of the cell Mg was found to be proportional to [Mg]o.3.
Vladimír Palatý
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Characterization of ectonucleotidases on vascular smooth-muscle cells [PDF]
Biochemical Journal, 1985 We compared the properties of the ectonucleotidases (nucleoside triphosphatase, EC 3.6.1.15; nucleoside diphosphatase, EC 3.6.1.6; 5′-nucleotidase, EC 3.1.3.5) in intact pig aortic smooth-muscle cells in culture with the properties that we previously investigated for ectonucleotidases of aortic endothelial cells [Cusack, Pearson & Gordon (1983 ...
Jeremy D. Pearson +2 more
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Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
Frontiers in Cardiovascular Medicine, 2022 Vascular smooth muscle cells (VSMCs) are the primary cell type involved in the atherosclerosis process; senescent VSMCs are observed in both aged vessels and atherosclerotic plaques.
Yiwen Zha +8 more
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Endothelial–Vascular Smooth Muscle Cells Interactions in Atherosclerosis
Frontiers in Cardiovascular Medicine, 2018 Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to cardiovascular disease (CVD). Despite available treatment, the prevalence of atherosclerotic CVD, which has become the leading cause of death worldwide, persists ...
Manna Li +3 more
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