Results 241 to 250 of about 513,814 (378)

The 9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State. [PDF]

Arterioscler Thromb Vasc Biol
Salido E, de Medeiros Vieira C, Mosquera JV, Zade R, Parikh P, Suryavanshi S, Miller CL, Lo Sardo V.   +7 more
europepmc   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

Advanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng, Yansong Wang, Haoyue Huang, Yinglong Ding, Jun Wang, Meili Liu, Kun Song, Lianbo Shao, You Yu, Ziying Yang, Zhenya Shen   +10 more
wiley   +1 more source

METTL3 obstructs vascular smooth muscle cells osteogenic reprogramming by methylating Runx2 in chronic kidney disease. [PDF]

Commun Biol
Cheng M, Jin J, Zhang D, Xiao M, Zhao H, Zhao X, Zhang S, Bai Y, Xu J.   +8 more
europepmc   +1 more source

Visualization of neural control of intracellular Ca2+ concentration in single vascular smooth muscle cells in situ. [PDF]

, 1994
Masamitsu Iino, Haruo Kasai, Toshiko Yamazawa   +2 more
openalex   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2. [PDF]

Ren Fail
Li L, Cheng M, Jin J, Zhao Y, Bai W, Zhang D, Zhang S, Bai Y, Xu J.   +8 more
europepmc   +1 more source

Simultaneous Measurements of Cytosolic Free Calcium Level and Prostaglandin Synthesis Reveal a Correlation between Them in Perfused Monolayer of Cultured Rat Vascular Smooth Muscle Cells: Effects of Bradykinin and Angiotensin II.

, 1991
Kazuhisa Takeuchi, Keishi Abe, Kazutaka Maeyama, Makito Sato, Minoru Yasujima, Takehiko Watanabe, KAORU YOSHINAGA   +6 more
openalex   +2 more sources

Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells [PDF]

, 1991
Martin Feelisch, Malte Kelm
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Estrogen Inhibits the Phenotypic Switching of Vascular Smooth Muscle Cells through ER-α/CREB in Aortic Dissection. [PDF]

ACS Omega
Pu Y, Zhou Y, Guo T, Chai X, Yang G.
europepmc   +1 more source