Results 61 to 70 of about 1,799,199 (341)

Arterial Stiffness – A Measurable Vascular Marker in Clinical Practice

APIK Journal of Internal Medicine, 2021
Arterial stiffness results from the changes in the walls of the large vessels and aorta. It has been incriminated in the pathogenesis of cardiovascular disorders. Its association with the major risk factors and atherosclerosis has been explored. Pulse wave velocity (PWV) is generally measured to evaluate it.
Nagaraj Desai, C R Venkatesh, Prabhakar Koregol   +2 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Technical Validation of ARTSENS–An Image Free Device for Evaluation of Vascular Stiffness

IEEE Journal of Translational Engineering in Health and Medicine, 2015
Vascular stiffness is an indicator of cardiovascular health, with carotid artery stiffness having established correlation to coronary heart disease and utility in cardiovascular diagnosis and screening. State of art equipment for stiffness evaluation are
Jayaraj Joseph, Ravikumar Radhakrishnan, Shitanshu Kusmakar, Arya Sree Thrivikraman, Mohanasankar Sivaprakasam   +4 more
doaj   +1 more source

Effect of antiretroviral therapy on decreasing arterial stiffness, metabolic profile, vascular and systemic inflammatory cytokines in treatment-naïve HIV: A one-year prospective study.

PLoS ONE, 2023
IntroductionCardiovascular disease is a major cause of death among people living with HIV (PLH). Non-treated PLH show increased levels of inflammation and biomarkers of vascular activation, and arterial stiffness as a prognostic cardiovascular disease ...
Pedro Martínez-Ayala, Guillermo Adrian Alanis-Sánchez, Monserrat Álvarez-Zavala, Karina Sánchez-Reyes, Vida Verónica Ruiz-Herrera, Rodolfo Ismael Cabrera-Silva, Luz Alicia González-Hernández, Carlos Ramos-Becerra, Ernesto Cardona-Muñoz, Jaime Federico Andrade-Villanueva   +9 more
doaj   +1 more source

Sox9 Accelerates Vascular Aging by Regulating Extracellular Matrix Composition and Stiffness

Circulation Research
BACKGROUND: Vascular calcification and increased extracellular matrix (ECM) stiffness are hallmarks of vascular aging. Sox9 (SRY-box transcription factor 9) has been implicated in vascular smooth muscle cell (VSMC) osteo/chondrogenic conversion; however,
Maria Faleeva, Sadia Ahmad, K. Theofilatos, S. Lynham, Gabriel Watson, M. Whitehead, Emilie Marhuenda, Thomas Iskratsch, Susan Cox, Catherine M. Shanahan   +9 more
semanticscholar   +1 more source

Deletion of the microRNA-degrading nuclease, translin/trax, prevents pathogenic vascular stiffness.

American Journal of Physiology. Heart and Circulatory Physiology, 2019
Vascular stiffness plays a key role in the pathogenesis of hypertension. Recent studies indicatethat the age associated reduction in miR-181b levels in vascular smooth muscle cells (VSMCs)contributes to increased vascular stiffness.
Eric Tuday, Yohei Nomura, Deepa Ruhela, Mitsunori Nakano, Xiuping Fu, Aparna P. Shah, B. Román, A. Yamaguchi, S. An, C. Steenbergen, J. Baraban, D. Berkowitz, Samarjit Das   +12 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Correlations between Vascular Stiffness Indicators, OPG, and 25-OH Vitamin D3 Status in Heart Failure Patients

Medicina, 2019
Background and objectives: The purpose of the study is to correlate vascular calcification biomarkers osteoprotegerin (OPG) and 25-hydroxyvitamin D3 (25-OH-D3), indicators of arterial stiffness carotid-femoral pulse wave velocity (c-f PWV) and renal ...
F. Buleu, C. Luca, A. Tudor, Marius Badalica-Petrescu, A. Caraba, A. Pah, D. Georgescu, R. Christodorescu, S. Dragan   +8 more
semanticscholar   +1 more source

Impact of Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitors on Arterial Stiffness and Vascular Aging—What Do We Know So Far? (A Narrative Review)

Life, 2022
Vascular aging, early vascular aging or supernormal vascular aging are concepts used for estimating the cardiovascular risk at a certain age. From the famous line of Thomas Sydenham that “a man is as old as his arteries” to the present day, clinical ...
C. Adam, R. Anghel, D. Marcu, O. Mitu, M. Roca, F. Mitu   +5 more
semanticscholar   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source