Chronic Diarrhea Caused by Vasoactive Intestinal Peptide-Secreting Tumor [PDF]
Life, 2023 VIPomas are a type of neuroendocrine tumor that independently produces vasoactive intestinal peptide (VIP). VIPomas causing watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome are not frequently observed in adult patients without pancreatic ...
Oana Belei +8 more
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Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration [PDF]
Frontiers in Oncology, 2022 Phosphoinositide metabolism is critically involved in human cancer cell migration and metastatic growth. The formation of lamellipodia at the leading edge of migrating cells is regulated by metabolism of the inositol phospholipid PI(4,5)P2 into PI(3,4,5 ...
Satoshi Asano +16 more
doaj +2 more sources
Pressure-Dependent Elevation of Vasoactive Intestinal Peptide Level in Chicken Choroid [PDF]
Biology, 2023 Purpose: Autonomic control is important in maintaining ocular integrity. As recent data suggested that intrinsic choroidal neurons (ICN), an intrinsic choroidal autonomic control, may regulate choroidal thickening via release of the vasodilative ...
Evgeny Privalov +5 more
doaj +2 more sources
Vasoactive intestinal peptide producing pheochromocytoma and intracardiac thrombosis [PDF]
Rare Tumors, 2021 A case of pheochromocytoma producing vasoactive intestinal peptide (VIP) and left ventricular thrombus in the absence of cardiomyopathy or wall motion abnormalities on echocardiogram is presented along with a review of the relevant literature.
Melody Hermel +4 more
doaj +2 more sources
Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss [PDF]
Heliyon, 2023 Neuropeptides are a group of peptides derived from precursor proteins synthesized in neuronal and nonneuronal cells. The classical functions of neuropeptides have been extensively studied in mammals, including neuromodulation in the central nervous ...
Carolina Muñoz-Flores +13 more
doaj +2 more sources
Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury [PDF]
Stem Cell Research & TherapyBackground Vasoactive intestinal peptide (VIP) is a neuronal peptide with prominent distribution along the enteric nervous system. While effects of VIP on intestinal motility, mucosal vasodilation, secretion, and mucosal immune cell function are well ...
Tatiana Agibalova +18 more
doaj +2 more sources
Pheochromocytoma Producing Vasoactive Intestinal Peptide [PDF]
Mayo Clinic Proceedings, 2002 The syndrome of watery diarrhea associated with hypokalemia and achlorhydria was originally described in 1958. Subsequently, this syndrome was shown to be caused by a neuroendocrine tumor secreting vasoactive intestinal peptide (VIP), and such tumors are almost always pancreatic in origin.
Stephen L, Smith +3 more
openaire +3 more sources
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma [PDF]
Nature Communications, 2022 Poor antitumor response of pancreatic cancer to immunotherapies is a major barrier to effective disease management. Herein we show that pancreatic cancers overexpress vasoactive intestinal peptide, and pharmacological inhibition of its signaling ...
Sruthi Ravindranathan +20 more
doaj +2 more sources
Chronic diarrhea related to neuroblastoma: the important role of vasoactive intestinal peptide in tumor pathology and survival [PDF]
BMC CancerBackground To analyze the correlation between vasoactive intestinal peptide (VIP) protein expression in neuroblastoma (NB) tumors and NB clinical features and prognosis. Methods Clinical data were collected from 91 patients with NB aged
Meng-ying Cao +4 more
doaj +2 more sources
Vasoactive intestinal peptide induces proliferation of human hepatocytes. [PDF]
, 2018 OBJECTIVES: Proliferation of hepatocytes in vitro can be stimulated by growth factors such as epidermal growth factor (EGF), but the role of vasoactive intestinal peptide (VIP) remains unclear.
Absood +54 more
core +3 more sources