Results 1 to 10 of about 82,899 (261)
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma [PDF]
Nature Communications, 2022 Poor antitumor response of pancreatic cancer to immunotherapies is a major barrier to effective disease management. Herein we show that pancreatic cancers overexpress vasoactive intestinal peptide, and pharmacological inhibition of its signaling ...
Sruthi Ravindranathan +20 more
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Chronic Diarrhea Caused by Vasoactive Intestinal Peptide-Secreting Tumor [PDF]
Life, 2023 VIPomas are a type of neuroendocrine tumor that independently produces vasoactive intestinal peptide (VIP). VIPomas causing watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome are not frequently observed in adult patients without pancreatic ...
Oana Belei +8 more
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Vasoactive intestinal peptide regulates ileal goblet cell production in mice
Physiological Reports, 2020 Innervation of the intestinal mucosa has gained more attention with demonstrations of tuft and enteroendocrine cell innervation. However, the role(s) these fibers play in maintaining the epithelial and mucus barriers are still poorly understood.
Luke A. Schwerdtfeger, Stuart A. Tobet
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Vasoactive intestinal peptide–VIPR2 signaling regulates tumor cell migration [PDF]
Frontiers in Oncology, 2022 Phosphoinositide metabolism is critically involved in human cancer cell migration and metastatic growth. The formation of lamellipodia at the leading edge of migrating cells is regulated by metabolism of the inositol phospholipid PI(4,5)P2 into PI(3,4,5 ...
Satoshi Asano +16 more
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Pressure-Dependent Elevation of Vasoactive Intestinal Peptide Level in Chicken Choroid [PDF]
Biology, 2023 Purpose: Autonomic control is important in maintaining ocular integrity. As recent data suggested that intrinsic choroidal neurons (ICN), an intrinsic choroidal autonomic control, may regulate choroidal thickening via release of the vasodilative ...
Evgeny Privalov +5 more
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Nature Communications, 2019 The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely ...
Ryan Hamnett +3 more
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Vasoactive intestinal peptide producing pheochromocytoma and intracardiac thrombosis [PDF]
Rare Tumors, 2021 A case of pheochromocytoma producing vasoactive intestinal peptide (VIP) and left ventricular thrombus in the absence of cardiomyopathy or wall motion abnormalities on echocardiogram is presented along with a review of the relevant literature.
Melody Hermel +4 more
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Immunomodulatory role of vasoactive intestinal peptide and ghrelin in Oncorhynchus mykiss [PDF]
Heliyon, 2023 Neuropeptides are a group of peptides derived from precursor proteins synthesized in neuronal and nonneuronal cells. The classical functions of neuropeptides have been extensively studied in mammals, including neuromodulation in the central nervous ...
Carolina Muñoz-Flores +13 more
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Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury [PDF]
Stem Cell Research & TherapyBackground Vasoactive intestinal peptide (VIP) is a neuronal peptide with prominent distribution along the enteric nervous system. While effects of VIP on intestinal motility, mucosal vasodilation, secretion, and mucosal immune cell function are well ...
Tatiana Agibalova +18 more
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F1000Research, 2019 Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Mari Iwasaki +2 more
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