Results 1 to 10 of about 808 (137)

Microglial Activation Is Associated With Vasoprotection in a Rat Model of Inflammatory Retinal Vasoregression [PDF]

open access: yesFrontiers in Physiology, 2021
Vascular dysfunction and vasoregression are hallmarks of a variety of inflammatory central nervous system disorders and inflammation-related retinal diseases like diabetic retinopathy.
Matthias Kolibabka   +2 more
exaly   +4 more sources

THE CAPABILITIES OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN CLINICAL PRACTICE: FOCUS ON VASOPROTECTION [PDF]

open access: yesРациональная фармакотерапия в кардиологии, 2015
Data of large-scale research that shows comprehensive abilities of an angiotensin converting enzyme (ACE) inhibitors in clinical practice were represented.
D. B. Nebieridze, A. S. Safaryan
doaj   +6 more sources

The Effects of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Erythropoietin, and Their Interactions in Angiogenesis: Implications in Retinopathy of Prematurity

open access: yesCells, 2022
Retinopathy of prematurity (ROP) is a leading cause of vision impairment and blindness in premature infants. Oxidative stress is implicated in its pathophysiology.
Thaonhi Cung   +2 more
doaj   +2 more sources

Empagliflozin Plays Vasoprotective Role in Spontaneously Hypertensive Rats via Activation of the SIRT1/AMPK Pathway [PDF]

open access: yesCells
Empagliflozin (EMPA), a sodium-glucose co-transporter 2 (SGLT2) inhibitor, prevents endothelial dysfunction, but its effects on vascular tone in hypertension remain unclear.
Monika Kloza   +4 more
doaj   +2 more sources

Early Intravenous Delivery of Human Brain Stromal Cells Modulates Systemic Inflammation and Leads to Vasoprotection in Traumatic Spinal Cord Injury

open access: yesStem Cells Translational Medicine, 2016
Spinal cord injury (SCI) is a life‐threatening condition with multifaceted complications and limited treatment options. In SCI, the initial physical trauma is closely followed by a series of secondary events, including inflammation and blood spinal cord ...
Alex Laliberté   +2 more
exaly   +2 more sources

Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca2+-Activated K+ Channels [PDF]

open access: yesNeural Plasticity, 2023
Hyperoside (Hyp), a kind of Chinese herbal medicine, exerts multiple therapeutic effects on many diseases. However, the role and mechanisms of Hyp in vascular pathophysiology in ischemic stroke need to be further established.
Wen-Ming Hong   +9 more
doaj   +2 more sources

Rationale of Basic and Cellular Mechanisms Considered in Updating the Staging System for Diabetic Retinal Disease [PDF]

open access: yesOphthalmology Science
Purpose: Hyperglycemia is a major risk factor for early lesions of diabetic retinal disease (DRD). Updating the DRD staging system to incorporate relevant basic and cellular mechanisms pertinent to DRD is necessary to better address early disease ...
M. Elizabeth Hartnett, MD   +12 more
doaj   +2 more sources

Common Polymorphisms in the RGMa Promoter Are Associated With Cerebrovascular Atherosclerosis Burden in Chinese Han Patients With Acute Ischemic Cerebrovascular Accident

open access: yesFrontiers in Cardiovascular Medicine, 2021
Repulsive guidance molecule a (RGMa) plays a vital role in the progression of numerous inflammatory diseases. However, whether it participates in atherosclerosis development is not known.
Qingzhe Hu   +5 more
doaj   +1 more source

Apigenin alleviates diabetic endothelial dysfunction through activating AMPK/PI3K/Akt/eNOS and Nrf2/HO‐1 signaling pathways

open access: yesFood Frontiers, 2023
Apigenin (4′,5,7‐trihydroxyflavone) is a natural flavone reported to present anti‐diabetic and anti‐oxidative bioactivities. The effect of apigenin to mitigate endothelial dysfunction in diabetes remains to be investigated. In the present study, the vaso‐
Lingchao Miao   +5 more
doaj   +1 more source

Troxerutin Stimulates Osteoblast Differentiation of Mesenchymal Stem Cell and Facilitates Bone Fracture Healing

open access: yesFrontiers in Pharmacology, 2021
Troxerutin (TRX), a semi-synthetic derivative of the natural bioflavonoid rutin, is a bioactive flavonoid widely abundant in various fruits and vegetables.
Xiao Yang   +6 more
doaj   +1 more source

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