Transcriptomic analysis of gene expression in mice treated with troxerutin. [PDF]
PLoS ONE, 2017 Troxerutin, a semi-synthetic derivative of the natural bioflavanoid rutin, has been reported to possess many beneficial effects in human bodies, such as vasoprotection, immune support, anti-inflammation and anti-aging.
Yuerong Wang +7 more
doaj +2 more sources
Vasoprotection and nephroprotection: links of the same chain [PDF]
Кардиоваскулярная терапия и профилактика, 1970 Recently, the perception of microalbuminuria (MAU) has progressed from an indicator of renal artery dysfunction to a marker of systemic endothelial dysfunction, predicting cardiovascular risk.
N. Sh. Zagidullin +2 more
doaj +1 more source
TRAIL inhibits oxidative stress in human aortic endothelial cells exposed to pro‐inflammatory stimuli [PDF]
Physiological Reports, 2020 Studies suggest that tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) has vasoprotective potential, as low levels of TRAIL cause accelerated vascular calcification, whereas exogenous TRAIL administration exhibits anti‐atherosclerotic ...
Hannah Forde +6 more
doaj +2 more sources
Combined therapy of arterial hypertension: focus on pleiotropic effects [PDF]
Кардиоваскулярная терапия и профилактика, 2007 The article is focused on the importance of adequate blood pressure (BP) control in arterial hypertension, as well as on pleiotropic treatment effects. The latter are especially important in combined therapy, that, as a rule, is needed to achieve target ...
D. B. Nebieridze
doaj +1 more source
Novel Insights into the Vasoprotective Role of Heme Oxygenase-1 [PDF]
International Journal of Hypertension, 2012 Cardiovascular risk factors contribute to enhanced oxidative stress which leads to endothelial dysfunction. These events trigger platelet activation and their interaction with leukocytes and endothelial cells, thus contributing to the induction of ...
Emanuela Marcantoni +4 more
doaj +2 more sources
ORGANO-PROTECTIVE EFFECTS OF NIFEDIPINE GITS IN PATIENTS WITH ARTERIAL HYPERTENSION
Российский кардиологический журнал, 2010 In total, 40 patients with various stages of arterial hypertension (AH) were examined. All patients received nifedipine GITS as monotherapy or in combination with hydrochlorothiazide for 6 months.
T. V. Adasheva +4 more
doaj +1 more source
Vasoprotection by Dietary Nitrate in Rats with Vitamin D3-Induced Vascular Calcification
Journal of Vascular DiseasesBackground/Objectives: Vascular calcification is a major contributor to cardiovascular mortality and disability. Here, we investigated whether dietary nitrate, an exogenous source of nitric oxide (NO), could inhibit vascular calcification in a rat model ...
Masashi Tawa +2 more
doaj +2 more sources
Scientific Reports, 2017 The transcription factor Kruppel-like factor 2 (KLF2) is a critical anti-inflammatory and anti-atherogenic molecule in vascular endothelium. Enhancing KLF2 expression and activity improves endothelial function and prevents atherosclerosis.
Yanni Xu +6 more
doaj +2 more sources
IEFFICACY OF INDAPAMIDE AND VALSARTAN COMBINED THERAPY PATIENTS WITH ARTERIAL HYPERTENSION AND METABOLIC DISORDERS [PDF]
Евразийский Кардиологический Журнал, 2014 Aim of the study: to study antihypertensive and organ-protective efficacy of indapamide and valsartan combined therapy hypertensive patients with high cardiovascular risk and metabolic disorders.
G. A. Khamidullaeva +4 more
doaj +2 more sources
Corylin Confers Vasoprotection via JDP2-Nrf2 Antioxidant Axis against Chronic Kidney Disease-Induced Smooth Muscle Cell Remodelling. [PDF]
J Cell Mol MedABSTRACT Vascular calcification is a pathological process involving vascular smooth muscle cells (VSMCs) phenotypic switching into osteoblast‐like cells within a calcium phosphate‐deposited environment. This transformation is a critical risk factor for cardiovascular morbidity and mortality in patients with hyperphosphatemia due to chronic kidney ...
Huang SE +9 more
europepmc +2 more sources