Results 181 to 190 of about 15,633 (213)

Direct measurement of VDAC–actin interaction by surface plasmon resonance [PDF]

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 2006
VDAC – a mitochondrial channel involved in the control of aerobic metabolism and apoptosis – interacts in vitro and in vivo with a wide repertoire of proteins including cytoskeletal elements.
Inge Roman
exaly   +2 more sources

VDAC

ACM Transactions on Graphics, 2020
We introduce carvable volume decomposition for efficient 3-axis CNC machining of 3D freeform objects, where our goal is to develop a fully automatic method to jointly optimize setup and path planning. We formulate our joint optimization as a volume decomposition problem which prioritizes minimizing the number of ...
Ali Mahdavi-Amiri   +4 more
openaire   +1 more source

Anti-Cancer Compounds Targeted to VDAC: Potential and Perspectives

open access: yesCurrent Medicinal Chemistry, 2018
Background VDAC (Voltage-Dependent Anion selective Channel) is a small family of abundant pore-forming proteins located in the outer mitochondrial membrane.
Vito De Pinto, Simona REINA
exaly   +2 more sources

Subcellular localization of VDAC in mitochondria and ER in the cerebellum [PDF]

open access: yesBiochimica Et Biophysica Acta - Bioenergetics, 2004
The voltage-dependent anion channel (VDAC) provides passage for adenine nucleotides, Ca2+ and other metabolites into and from mitochondria. Here, the intracellular localization and oligomeric organization of VDAC in brain mitochondria and ER are ...
Varda Shoshan-Barmatz, Ran Zalk
exaly   +2 more sources

On the Role of VDAC in Apoptosis: Fact and Fiction

Journal of Bioenergetics and Biomembranes, 2005
Research on VDAC has accelerated as evidence grows of its importance in mitochondrial function and in apoptosis. New investigators entering the field are often confounded by the VDAC literature and its many apparent conflicts and contradictions.
Tatiana K Rostovtseva   +2 more
exaly   +3 more sources

Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs [PDF]

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 2012
Three isoforms of the human voltage-dependent anion channel (VDAC), located in the outer mitochondrial membrane, are crucial regulators of mitochondrial function.
Tsyr-Yan Yu   +2 more
exaly   +2 more sources

Intracellular localization of VDAC proteins in plants [PDF]

open access: possiblePlanta, 2004
Voltage-dependent anion channels (VDACs) are porin-type beta-barrel diffusion pores. They are prominent in the outer membrane of mitochondria and facilitate metabolite exchange between the organelle and the cytosol. Here we studied the subcellular distribution of a plant VDAC-like protein between plastids and mitochondria in green and non-green tissue.
Clausen, Cathrin   +8 more
openaire   +2 more sources

Specific VDAC inhibitors: phosphorothioate oligonucleotides

Journal of Bioenergetics and Biomembranes, 2008
VDAC channels are ancient, highly-conserved voltage-gated channels in the mitochondrial outer membrane. They are the pathways by which metabolites travel between the cytosol and mitochondria. They are involved in the apoptotic process and probably other functions as well.
C A, Stein, Marco, Colombini
openaire   +2 more sources

VDAC, a Channel in the Outer Mitochondrial Membrane

1996
Proteins that form aqueous channels in membranes generate conduction pathways with a variety of shapes and sizes. Perhaps the largest channel-forming protein is the 2-MDa ryanodine receptor while the smallest may be gramicidin. However, the size of the conducting pathway is not correlated with the amount of protein mass needed to make up the structure,
M, Colombini, E, Blachly-Dyson, M, Forte
openaire   +2 more sources

Role of Hexokinase and VDAC in Neurological Disorders

Current Molecular Pharmacology, 2016
Several neurological diseases such as bipolar disorders and schizophrenia are linked to impaired brain energy metabolism. A key feature of brain bioenergetics is hexokinase (HK) binding to the outer mitochondrial membrane through the voltage dependent anion channel (VDAC).
José César, Rosa   +1 more
openaire   +2 more sources

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