IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer [PDF]
Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP3 receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival.
Alzayady, Kamil J. +13 more
core +1 more source
Esophageal squamous cell carcinoma (ESCC) is one of the most common digestive malignancies. Our previous studies revealed necroptosis-related lncRNA ENSG00000253385.1 was an independent prognostic factor for ESCC.
X. Duan +5 more
semanticscholar +1 more source
Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice
Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive.
Dongyun Wang +12 more
doaj +1 more source
Evaluation of Porin Interaction with Adenine Nucleotide Translocase and Cyclophilin-D Proteins after Brain Ischemia and Reperfusion [PDF]
Objective (s) Porin is a mitochondrial outer membrane channel, which usually functions as the pathway for the movement of various substances in and out of the mitochondria and is considered to be a component of the permeability transition (PT) pore ...
Jose Luis Perez Velazquez +1 more
core
Novel heterozygous mutation in the steroidogenic acute regulatory protein gene in a 46,XY patient with congenital lipoid adrenal hyperplasia [PDF]
StAR forma parte del complejo multiproteico transduceosoma, encargado del transporte de colesterol y que facilita su entrada a la mitocondria. Mutaciones recesivas en el gen STAR causan formas clásicas y no clásicas de hiperplasia adrenal congénita ...
Bailez, Marcela +10 more
core +1 more source
Tumor suppressive Ca2+ signaling is driven by IP3 receptor fitness [PDF]
Bultynck, G, Campanella, M
core +3 more sources
Targeting VDAC1 to protect against mitochondria-linked cell death pathways: apoptosis, pyroptosis, ferroptosis, and associated diseases. [PDF]
Shteinfer-Kuzmine A +6 more
europepmc +1 more source
Mitochondrial DNA release via VDAC1 in keratinocytes: a key driver of innate immunity and vitiligo pathogenesis. [PDF]
Lv J +9 more
europepmc +1 more source
Self-assembled nanoparticles from Xiexin Decoction attenuate ulcerative colitis by targeting VDAC1-Mediated NLRP3 inflammasome activation. [PDF]
Chu Z +15 more
europepmc +1 more source
VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy. [PDF]
Bi Y +10 more
europepmc +1 more source

