Results 111 to 120 of about 11,641 (203)

ANALISIS EKSPRESI DAN MUTASI PROMOTER GEN BAX,BCL2 DAN VDAC1 PADA PASIEN OLIGOZOOSPERMIA

, 2015
Salah satu faktor penyebab keadaan oligozoospermia adalah terjadinya apoptosis yang berlebihan pada proses spermatogenesis. Telah diketahui bahwa proses spermatogenesis melibatkan protein keluarga Bcl2 yang terletak di sitoplasma dan protein kanal ion ...
ARNI, AMIR
core   +1 more source

Expression profile of mitochondrial voltage-dependent anion channel-1 (VDAC1) influenced genes is associated with pulmonary hypertension

, 2017
Several human diseases have been associated with mitochondria! voltage-dependent anion channel-1 (VDAC1) due to its role in calcium ion transportation and apoptosis.
Dustin Fraidenburg, Zhou, Tong, Donghee Lee, Jae-Hong Ko, Kim, Young-Won, Lee, Donghee, Jeongyoon Choi, Han, Ying, Tong Zhou, Choi, Jeongyoon, Hyoweon Bang, Haiyang Tang, Ying Han, Tang, Haiyang, Young-Won Kim, Fraidenburg, Dustin, Ko, Jae-Hong, Bang, Hyoweon   +17 more
core   +1 more source

Role of VDAC1 hypoxic form, VDAC1-∆C, in the expression of primary cilia and tumor progression

Rôle de la forme hypoxique VDAC1, VDAC1-∆C, dans l’expression du cil primaire et la progression tumorale Le voltage-dependent anion channel 1 (VDAC1) est une porine exprimée au niveau de la membrane externe des mitochondries et qui joue un rôle très important dans la régulation du métabolisme cellulaire et de l'apoptose.
openaire   +2 more sources

LncRNA H19 inhibition impairs endoplasmic reticulum-mitochondria contact in hepatic cells and augments gluconeogenesis by increasing VDAC1 levels

Redox Biology
Inspite of exerting independent cellular functions, the endoplasmic-reticulum (ER) and the mitochondria also physically connect at specific sites termed mitochondria-associated ER membranes (MAMs) and these sites consist of several tethering proteins ...
Arun Nandwani, Shalu Rathore, Malabika Datta   +2 more
doaj   +1 more source

VDAC1 Gene [PDF]

, 2020
openaire   +1 more source

Post-Translationally Modified Cardiac Mitochondrial VDAC1 Gating Kinetics Analyzed Using Continuous-Time MCMC Model

, 2013
Mitochondrial homeostasis, maintained via the outer mitochondrial membrane (OMM), is critical for maintaining mitochondrial function. The voltage-dependent anion channel (VDAC1 isoform) is the most abundant protein on the OMM, and it regulates the ...
Shiv Tewari (422641)
core   +1 more source

The anticancer effect of metformin targets VDAC1 via ER-mitochondria interactions-mediated autophagy in HCC

Experimental and Molecular Medicine
Metformin (MetF) is used worldwide as a first-line therapy for type 2 diabetes. Recently, interest in the pleiotropic effects of MetF, such as its anticancer and antiaging properties, has increased.
Minjeong Ko, Jiho Kim, Raudah Lazim, Ju Yeon Lee, Jin Young Kim, Vijayakumar Gosu, Yoonji Lee, Sun Choi, Ho Jeong Kwon   +8 more
doaj   +1 more source

Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice

Cell Death Discovery
Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive.
Dongyun Wang, Yue Li, Guiying Li, Mengyu Liu, Zihui Zhou, Ming Wu, Shan Song, Yawei Bian, Jiajia Dong, Xinran Li, Yunxia Du, Tao Zhang, Yonghong Shi   +12 more
doaj   +1 more source

VDAC1 as Janus in cell death and survival : Annexin A5 to the rescue

VDAC1, a large conductance channel in the outer mitochondrial membrane, plays a crucial role in mitochondrial physiology. VDAC1 supports cellular metabolism and survival by serving as a mitochondrial $Ca^{2+}$-uptake and ATP-exit system.
Champion, Ophélie, Litewka, Jacek, Bultynck, Geert, Ferdek, Paweł   +3 more
core   +1 more source

VDAC1 wt Allele [PDF]

, 2020
openaire   +1 more source