Results 151 to 160 of about 9,347 (172)

RfeA from Streptococcus suis serotype 2 triggers NLRP3/Caspase-1-dependent pyroptosis leading to blood-brain barrier disruption. [PDF]

Vet Res
Gao S, Wu W, Xiao X, Li J, Lei S, Wang L, Han X, Lou Y.   +7 more
europepmc   +1 more source

USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression. [PDF]

Cell Death Dis
Haowei Z, Li X, Liao W, Qin X, Jiang Y, Yang H, Zeng H, Li Y, Xie W, Zhang Y, Xu N.   +10 more
europepmc   +1 more source

Copper loading may affect rat neurobehaviour by impairing mitochondria-associated endoplasmic reticulum membranes in hippocampal neurons. [PDF]

Behav Brain Funct
Sun Z, Jin S, Fang X, Yang W, Chen H.
europepmc   +1 more source

Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca²⁺ flux through MAMs. [PDF]

Front Cardiovasc Med
Li Y, Du T, Zhang Y, Lu Y, Li X, Xie W, Guo S.   +6 more
europepmc   +1 more source

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ANP32B promotes lung cancer progression by regulating VDAC1

Gene, 2023
It has been reported before that acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) plays roles in many cancers, yet no report of its role in lung cancer exists. In this study, we documented an elevation of ANP32B within lung cancer tissues and cells. Knockdown of ANP32B hindered the proliferation as well as migration of lung cancer
Tiezhi, Li, Na, Wang, Shujun, Li, Hongjiang, Yan, Shaolin, Gao, Weinian, Gao, Ruoxuan, Xu   +6 more
openaire   +2 more sources

WDR26/MIP2 interacts with VDAC1 and regulates VDAC1 expression levels in H9c2 cells

Free Radical Biology and Medicine, 2018
MIP2, one of WDR26 isoforms, encodes a 498 amino acid protein with an amino-terminal CTLH domain and five carboxyl-terminal WD40 motifs. MIP2 is localized to the mitochondria and protects cardiomyocytes against oxidative stress; however, nothing is known about how MIP2 confers its cytoprotection.
Lei, Jiang, Hao, Wang, Guangbin, Chen, Yansheng, Feng, Jiang, Zou, Meidong, Liu, Ke, Liu, Nian, Wang, Huali, Zhang, Kangkai, Wang, Xianzhong, Xiao   +10 more
openaire   +2 more sources

Purification of VDAC1 from Rat Liver Mitochondria

Cold Spring Harbor Protocols, 2013
To make biophysical measurements of functions such as the pore-forming activity of mitochondrial voltage-dependent anion-selective channel protein 1 (VDAC1), it is first necessary to obtain a source of purified VDAC protein. In this protocol, we present a method for obtaining rat liver mitochondria as a source of VDAC1 and then describe two methods ...
Danya, Ben-Hail, Varda, Shoshan-Barmatz
openaire   +2 more sources

Dominant-negative VDAC1 mutants reveal oligomeric VDAC1 to be the active unit in mitochondria-mediated apoptosis

Biochemical Journal, 2010
Mitochondria play a central role in the intrinsic pathway of apoptosis. Oligomerization of the mitochondrial protein VDAC1 (voltage-dependent anion channel 1) has been proposed to play a role in apoptosis in various studies. In the present study, we have generated dimeric fusion proteins consisting of tandem-linked wild-type and RuR (Ruthenium Red ...
Asaf, Mader, Salah, Abu-Hamad, Nir, Arbel, Manuel, Gutiérrez-Aguilar, Manuel, Gutierr-Asuilar, Varda, Shoshan-Barmatz   +5 more
openaire   +2 more sources

UBA52 attunes VDAC1-mediated mitochondrial dysfunction and dopaminergic neuronal death

ACS Chemical Neuroscience, 2022
AbstractMitochondrial homeostasis regulates energy metabolism, calcium buffering, cell function and apoptosis. The present study has been conducted to investigate the implications of ubiquitin-encoding gene UBA52 in mitochondrial physiology. Transient expression of Myc-UBA52 in neurons significantly inhibited the rotenone-induced increase in reactive ...
Shubhangini Tiwari, Abhishek Singh, Parul Gupta, Amrutha K, Sarika Singh   +4 more
openaire   +2 more sources