Results 161 to 170 of about 11,641 (203)

Effects of homozygous PARK7 gene mutations L166P and M26I on BNIP3/BNIP3L interactions and ER-mitochondria proximity. [PDF]

Biol Direct
Wu J, Jin K, Shen M, Lai X, Guo J, Wang T, Tian Z, Yan J.   +7 more
europepmc   +1 more source

A prognostic model for breast cancer based on mitochondria-associated endoplasmic reticulum membrane (MAM) signature genes. [PDF]

Discov Oncol
Cui J, Wei L, Xu B, Han S, Guo C, Wang X.   +5 more
europepmc   +1 more source

Pestivirus bovine viral diarrhea virus infection induces ROS-HIF-1a axis-driven glycolytic reprogramming, which increases viral replication by impairing RIG-I-dependent type I interferon response. [PDF]

J Virol
Li Y, Zhou J, Wang J, Yan K, Guan Y, Wang M, Xiang J, Liu Y, Yu H, Jia S, Yang W, Xu 徐义刚 Y.   +11 more
europepmc   +1 more source

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review). [PDF]

Mol Med Rep
Meng S, Fu X, Xu Y, Peng Z, Zhang X, Cao Y, Tang B, Shi X, Liu K.   +8 more
europepmc   +1 more source

Mitochondria-associated endoplasmic reticulum membrane (MAM): roles in innate immunity dysregulation. [PDF]

Cell Commun Signal
Zhang Q, Gao J, Yang Y, Guo P, Gao H, Zhao S, Zhang S, Shi Y, Xie G, Han Y, Liu H, Zou Y.   +11 more
europepmc   +1 more source

Mitochondrial DNA release via VDAC1 in keratinocytes: a key driver of innate immunity and vitiligo pathogenesis. [PDF]

Cell Death Dis
Lv J, Xu W, Jiang P, Yu W, Xue H, Hu N, Cao Y, Zhang H, Yin C, Gao R.   +9 more
europepmc   +1 more source

VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and Diseases

Biomolecules, 2020
The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for cellular fate.
Varda Shoshan-Barmatz, Anna Shteinfer-Kuzmine   +1 more
exaly   +6 more sources

VDAC1: A Key Player in the Mitochondrial Landscape of Neurodegeneration

Biomolecules
Voltage-Dependent Anion Channel 1 (VDAC1) is a mitochondrial outer membrane protein that plays a crucial role in regulating cellular energy metabolism and apoptosis by mediating the exchange of ions and metabolites between mitochondria and the cytosol ...
Adrian Israelson, Joy Kahn, Shirel Argueti-Ostrovsky   +2 more
exaly   +5 more sources

VDAC1-interacting anion transport inhibitors inhibit VDAC1 oligomerization and apoptosis

Biochimica Et Biophysica Acta - Molecular Cell Research, 2016
Mitochondria-mediated apoptosis involves pro-apoptotic protein release from the mitochondria to the cytosol, triggering apoptosis. However, the mechanisms by which apoptotic initiators cross the outer mitochondrial membrane (OMM) remain unclear. The voltage-dependent anion channel 1 (VDAC1), an OMM protein, is central to mitochondria-mediated apoptosis.
Varda Shoshan-Barmatz, Danya Ben-Hail
exaly   +3 more sources

Targeting the Mitochondrial Protein VDAC1 as a Potential Therapeutic Strategy in ALS

International Journal of Molecular Sciences, 2022
Impaired mitochondrial function has been proposed as a causative factor in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), caused by motor neuron degeneration. Mutations in superoxide dismutase (SOD1) cause ALS and SOD1 mutants
Uttpal Anand, Varda Shoshan-Barmatz, Adrian Israelson   +2 more
exaly   +2 more sources