Results 181 to 190 of about 11,641 (203)
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Hypoxic VDAC1: A Potential Mitochondrial Marker for Cancer Therapy
2013Finding new therapeutic targets to fight cancer is an ongoing quest. Because of insufficiencies in tumor vasculature, cells often are exposed to a hostile microenvironment that is low in oxygen (hypoxic) and nutrients. Thus, tumor cells face the challenge of finding new sources of energy and defying apoptosis, which allow them to survive, grow, and ...
M Christiane, Brahimi-Horn, N M, Mazure
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Lipids influence the oligomeric organization of VDAC1
Biophysical JournalThe voltage-dependent anion channel (VDAC) is a mitochondrial outer membrane (MOM) β-barrel protein allowing passage of ions and metabolites (such as ATP, ADP, NADH⋯) in and out of the mitochondria. Besides its transport function, VDAC is implicated in mitochondrial regulation with roles in apoptosis, calcium homeostasis or neurodegeneration.
Lafargue, Elodie +5 more
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Mitochondrinio baltymo VDAC1 klonavimas
2014Įvadas VDAC1 (angl. Voltage Dependent Anion Channel 1) priklauso jonų kanalų šeimai, kurios baltymai vykdo jonų transportą tarp citozolio ir mitochondrijų vidaus [1], tačiau per įvairias sąveikas su kitais baltymais VDAC1 tampa labai svarbus reguliuojant ląstelės gyvybės ir žūties procesus [2].
Gricius, Dovydas, Borutaitė, Vilmantė
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Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination
Proceedings of the National Academy of Sciences of the United States of America, 2020Su Jin Ham +2 more
exaly
Oligomerization of the Mitochondrial Protein VDAC1
2013Varda Shoshan-Barmatz +2 more
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