Results 181 to 190 of about 11,641 (203)
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Hypoxic VDAC1: A Potential Mitochondrial Marker for Cancer Therapy

2013
Finding new therapeutic targets to fight cancer is an ongoing quest. Because of insufficiencies in tumor vasculature, cells often are exposed to a hostile microenvironment that is low in oxygen (hypoxic) and nutrients. Thus, tumor cells face the challenge of finding new sources of energy and defying apoptosis, which allow them to survive, grow, and ...
M Christiane, Brahimi-Horn, N M, Mazure
openaire   +2 more sources

Lipids influence the oligomeric organization of VDAC1

Biophysical Journal
The voltage-dependent anion channel (VDAC) is a mitochondrial outer membrane (MOM) β-barrel protein allowing passage of ions and metabolites (such as ATP, ADP, NADH⋯) in and out of the mitochondria. Besides its transport function, VDAC is implicated in mitochondrial regulation with roles in apoptosis, calcium homeostasis or neurodegeneration.
Lafargue, Elodie   +5 more
openaire   +2 more sources

Mitochondrinio baltymo VDAC1 klonavimas

2014
Įvadas VDAC1 (angl. Voltage Dependent Anion Channel 1) priklauso jonų kanalų šeimai, kurios baltymai vykdo jonų transportą tarp citozolio ir mitochondrijų vidaus [1], tačiau per įvairias sąveikas su kitais baltymais VDAC1 tampa labai svarbus reguliuojant ląstelės gyvybės ir žūties procesus [2].
Gricius, Dovydas, Borutaitė, Vilmantė
openaire   +1 more source

Decision between mitophagy and apoptosis by Parkin via VDAC1 ubiquitination

Proceedings of the National Academy of Sciences of the United States of America, 2020
Su Jin Ham   +2 more
exaly  

NOVEL VDAC1 INHIBITORS

2022
BROWN WILLIAM DALBY   +2 more
openaire   +2 more sources

Oligomerization of the Mitochondrial Protein VDAC1

2013
Varda Shoshan-Barmatz   +2 more
openaire   +1 more source

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