The endometrial expression level of estrogen-α and VEGF-A in female rats administered with a low dose of estrogen in early clomiphene citrate therapy [PDF]
Iraqi Journal of Veterinary Sciences, 2023 The study was conducted to determine the effect of low-dose estrogen in the early cycle of clomiphene citrate therapy on the expression of level estrogen receptor α (ERα) and VEGF-A in the endometrium.
Rahmat L. Landahur +3 more
doaj +1 more source
Expression of functional eGFP-fused antigen-binding fragment of ranibizumab in Pichia pastoris [PDF]
BioImpacts, 2022 Introduction: Ranibizumab is a mouse monoclonal antibody fragment antigen-binding (Fab) against human vascular endothelial growth factor-A (VEGF-A), inhibiting angiogenesis.
Shirin Movaghar Asareh +6 more
doaj +1 more source
VEGF: a critical player in neurodegeneration [PDF]
Journal of Clinical Investigation, 2004 VEGF is a prototype angiogenic factor, but recent evidence indicates that this growth factor also has direct effects on neural cells. Abnormal regulation of VEGF expression has now been implicated in several neurodegenerative disorders, including motoneuron degeneration.
Erik, Storkebaum, Peter, Carmeliet
openaire +2 more sources
Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
, 2013 We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Chillo, Omary +6 more
core +6 more sources
Association of VEGF cytokine levels and single nucleotide polymorphisms of the VEGF-A gene with the genital endometriosis in the female population of the Northwestern Federal District of Russia [PDF]
Гинекология, 2022 Aim. To study the association of neoangiogenesis VEGF-A gene polymorphisms C(-460)T (rs833061), C(+936)T (rs3025039) with the risk of genital endometriosis in the population of the Northwestern Federal District; to examine the relationship of polymorphic
Natalia V. Kulikova +3 more
doaj +1 more source
Zaporožskij Medicinskij Žurnal, 2022 Extracellular small vesicles – exosomes, attract the attention of researchers as a promising tool for regulating intercellular communication. At the same time, the therapeutic effects achieved through the use of mesenchymal stem cells (MSCs) are ...
L. V. Natrus +6 more
doaj +1 more source
Embryonic Vascular Toxicity of Calotropis Procera; Evaluation of Early Anti-Vasculogenic Property and Molecular Aspects Using A Chick’s Extra-Embryonic Membrane Model [PDF]
International Journal of Nutrition Sciences, 2019 Background: Calotropis procera Aiton (C. procera) is used in folk medicine to cure various diseases. However, the use of herbs in human medicine is sometimes associated with adverse effects.
Hadi Tavakkoli +6 more
doaj +1 more source
VEGF-A related SNPs: a cardiovascular context
Frontiers in Cardiovascular Medicine, 2023 Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Currently, cardiovascular disease risk algorithms play a role in primary prevention. However, this is complicated by a lack of powerfully predictive biomarkers that could be observed in individuals before the onset of overt symptoms.
Meza-Alvarado JC +4 more
openaire +4 more sources
Positive and negative regulation of angiogenesis by soluble vascular endothelial growth factor receptor-1 [PDF]
, 2018 Vascular endothelial growth factor receptor (VEGFR)-1 exists in different forms, derived from alternative splicing of the same gene. In addition to the transmembrane form, endothelial cells produce a soluble VEGFR-1 (sVEGFR-1) isoform, whereas non ...
Carbo, Miriam +2 more
core +6 more sources
Acta Medica Alanya, 2020 Aim: Paracetamol is widely used by important societal groups such as pregnant women and the elderly. Paracetamol, taken in high doses especially during pregnancy, causes liver failure.
Seher Yi̇lmaz +6 more
doaj +1 more source