Results 51 to 60 of about 383,810 (341)

Expression levels of vascular endothelial growth factors A and C in patients with peptic ulcers and gastric cancer [PDF]

, 2014
Purpose: Vascular endothelial growth factor (VEGF) is one of the most important growth factors for metastatic tumors. To clarify the role of VEGF-A and C in patients with peptic ulcer disease (PUD) or gastric cancer (GC), we evaluated the expression ...
Abbasi, A., Ajami, A., Ajami, M., Farazmandfar, T., Hafezi, N., Hosseini, V., Mohammadian, R., Sankian, M., Taghizadeh, S., Tehrani, M.   +9 more
core   +2 more sources

Vascular endothelial growth factor attenuates enhanced spontaneous transdifferentiation of classical and intermediate monocytes in patients with ischemic cardiomyopathy

Сеченовский вестник
Aim. To evaluate the effect of vascular endothelial growth factor A (VEGF-A) on the subpopulation composition of monocytes in the blood mononuclear cell culture of patients with coronary heart disease (CHD), with and without ischemic cardiomyopathy (ICMP)
M. V. Gladkovskaya, S. P. Chumakova, O. I. Urazova, V. S. Poletika, V. M. Shipulin, S. L. Andreev   +5 more
doaj   +1 more source

Utilization of a chicken embryo membrane model for evaluation of embryonic vascular toxicity of Dorema ammoniacum [PDF]

Avicenna Journal of Phytomedicine, 2020
Objective: Extensive research has been done to assess the efficacy of herbs for treating different disorders. Dorema ammoniacum (D. ammoniacum) is used in folk medicines for various goals.
Hadi Tavakkoli, Amin Derakhshanfar, Javad Moayedi, Ali Poostforoosh Fard   +3 more
doaj   +1 more source

Regulation of VEGF-A expression and VEGF-A-targeted therapy in malignant tumors

Journal of Cancer Research and Clinical Oncology
AbstractVascular endothelial growth factor A (VEGF-A), a highly conserved dimeric glycoprotein, is a key regulatory gene and a marker molecule of angiogenesis. The upregulation of VEGF-A facilitates the process of tumor vascularization, thereby fostering the initiation and progression of malignant neoplasms.
Kang, Yan, Li, Huiting, Liu, Yiping, Li, Zheng   +3 more
openaire   +2 more sources

Mutated TP53 is a marker of increased VEGF expression: analysis of 7,525 pan-cancer tissues. [PDF]

, 2020
Anti-angiogenic therapies are an important class of anti-cancer treatment drugs. However, their efficacy is limited to certain tumors and would benefit from identifying a biomarker predictive of therapeutic response.
Boichard, Amélie, Kurzrock, Razelle, Li, Alex M   +2 more
core  

Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension [PDF]

, 2018
Right ventricular (RV) function is the primary prognostic factor for both morbidity and mortality in pulmonary hypertension (PH). RV hypertrophy is initially an adaptive physiological response to increased overload; however, with persistent and/or ...
Bonnet, Sébastien, de Jesus Perez, Vinicio A., Frump, Andrea L., Lahm, Tim   +3 more
core   +1 more source

Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?

Clinics
OBJECTIVE: The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. METHOD: Adult Sprague-Dawley female rats were divided into four groups (n=6 per group):
Camila do Valle Gomes-Gatto, Fernanda Oliveira Duarte, Uliana Sbeguen Stotzer, Maria Fernanda Cury Rodrigues, Sérgio Eduardo de Andrade Perez, Heloisa Sobreiro Selistre-de-Araujo   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source