Results 81 to 90 of about 383,810 (341)

Investigation of the Effect of High-Intensity Interval Training (HIIT) on the Expression of the Genes miR-126, miR-296, HGS and VEGF-A Protein Levels in Tumor Tissue in Female Mice [PDF]

Journal of Advanced Biomedical Sciences, 2021
Background & Objective: The studies of the last two decades have shown that regular training is associated with the reduction of mortality among patients with breast cancer, and has an important role in inhibiting breast cancer progression as well as ...
Mahdiyeh Nasiri Ivanaki, Sirous Farsi, Hadi Ghaedi   +2 more
doaj  

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Pioglitazone Prevents Capillary Rarefaction in Streptozotocin-Diabetic Rats Independently of Glucose Control and Vascular Endothelial Growth Factor Expression [PDF]

, 2012
Background/Aims: Reduction of capillary network density occurs early in the development of metabolic syndrome and may be relevant for the precipitation of diabetes.
Andreas Dendorfer, Arany Z, Astrid Ashoff, Baraka A, Battegay EJ, Billiet L, Biscetti F, Blasi ER, Chintalgattu V, Cipolla MJ, Dendorfer A, Duan SZ, Emanueli C, Emoto M, Fatimunnisa Qadri, Frisbee JC, Frisbee JC, Frisbee JC, Gealekman O, Geraldes P, Goodwill AG, Han B, Heidbreder M, Kobayashi N, Levy BI, Lillioja S, Lindenmeyer MT, Nishikawa T, Noon JP, Ohga S, Olaf Jöhren, Polikandriotis JA, Prewitt RL, Redondo S, Reinhard Eggers, Romeo G, Son NH, Thangarajah H, Vogt CJ, Walter Raasch, Weidner N, Yue Tl TL, Zolk O   +42 more
core   +1 more source

miR-124, miR-126-3p, and miR-200b: Potential therapeutic targets for VEGF-mediated complications in proliferative diabetic retinopathy

Indian Journal of Ophthalmology
Introduction: This study aimed to investigate alterations in intravitreal microRNA and vascular endothelial growth factor (VEGF) levels in patients with proliferative diabetic retinopathy (PDR) as these factors are implicated in PDR pathogenesis. Methods:
Irfan Akaray, Sadık Altan Ozal, Hilal Sancar, Ece Ozal, Lokman Ayaz   +4 more
doaj   +1 more source

Serum cytokine levels in breast cancer patients during neoadjuvant treatment with bevacizumab

OncoImmunology, 2018
A high concentration of circulating vascular endothelial growth factor (VEGF) in cancer patients is associated with an aggressive tumor phenotype. Here, serum levels of 27 cytokines and blood cell counts were assessed in breast cancer patients receiving ...
Shakila Jabeen, Manuela Zucknick, Marianne Nome, Ruth Dannenfelser, Thomas Fleischer, Surendra Kumar, Torben Lüders, Hedda von der Lippe Gythfeldt, Olga Troyanskaya, Jon Amund Kyte, Anne-Lise Børresen-Dale, Bjørn Naume, Xavier Tekpli, Olav Engebraaten, Vessela Kristensen   +14 more
doaj   +1 more source

INTERRELATIONSHIP OF THE MEDIATOR OF ANGIOGENESIS OF VEGF-A WITH GLUTATHIONE METABOLISM PARAMETERS AND THE CLINICAL CHARACTERISTICS OF SYSTEMIC AUTOIMMUNE DISEASES WITH JOINT DAMAGE

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2019
Introduction. In systemic autoimmune diseases with joint damage (SADJD), impaired angiogenesis occurs, which plays a key role in the progression of proliferative synovitis and in the development of lesions of the internal organs.
L. A. Alexandrova, N. A. Filippova, A. Iman, T. F. Subbotina, V. I. Trofimov   +4 more
doaj   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Metformin: a modulator of bevacizumab activity in cancer? A case report. [PDF]

, 2015
Recurrent type I endometrial cancer ((EC)) has poor prognosis and demands novel therapeutic approaches. Bevacizumab, a VEGF-A neutralizing monoclonal antibody, has shown clinical activity in this setting. To our knowledge, however, although some diabetic
Aliberti, C, Casarin, A, Indraccolo, Stefano, Nardin, M, Nicoletto, Mo, Pomerri, Fabio, Randon, G, Zulato, E   +7 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Pancreatic Cyst Fluid Vascular Endothelial Growth Factor A and Carcinoembryonic Antigen: A Highly Accurate Test for the Diagnosis of Serous Cystic Neoplasm [PDF]

, 2017
Background Accurate differentiation of pancreatic cystic lesions is important for early detection and prevention of pancreatic cancer, as well as avoidance of unnecessary surgical intervention. Serous cystic neoplasms (SCNs) have no malignant potential,
Carr, Rosalie A., Dolejs, Scott, Hancock, Bradley A., Radovich, Milan, Schmidt, C. Max, Wu, Huangbing, Yip-Schneider, Michele T.   +6 more
core   +1 more source