Results 41 to 50 of about 20,098,805 (300)
, 2022 The phase III MAX clinical trial randomised patients with metastatic colorectal cancer (mCRC) to receive first-line capecitabine chemotherapy alone or in combination with the anti-VEGF-A antibody bevacizumab (± mitomycin C).
Niall Tebbutt (13124949) +15 more
core +1 more source
Serum vascular endothelial growth factor (VEGF-C) as a diagnostic and prognostic marker in patients with ovarian cancer. [PDF]
PLoS ONE, 2013 VEGF-C is regarded as one of the most efficient factors in regulating lymphangiogenesis. The aim of this study was to better understand the role of VEGF-C in the progression of ovarian cancer and to assess its diagnostic and prognostic significance.
Daye Cheng, Bin Liang, Yunhui Li
doaj +1 more source
Indian Journal of Pathology and MicrobiologyBackground: Vascular Endothelial Growth Factor-C (VEGF-C) plays a critical role in tumor growth and invasion through lymphangiogenesis and helps to identify the variability of lymphatic potential of oral squamous cell carcinoma (OSCC) cases with or ...
Ankita Tandon +3 more
doaj +1 more source
Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells. [PDF]
PLoS ONE, 2016 Elevated serum interleukin-6 (IL-6) levels correlates with tumor grade and poor prognosis in cancer patients. IL-6 has been shown to promote tumor lymphangiogenesis through vascular endothelial growth factor-C (VEGF-C) induction in tumor cells.
Yu-Han Huang +5 more
doaj +1 more source
Analytical Cellular Pathology, 2015 In this study 80 malignant CMT were submitted to immunohistochemical detection of CD3, c-kit, VEGF, and CD31, together with clinicopathological parameters of tumor aggressiveness. CD3+ T-cells and c-kit overexpression revealed a positive correlation with
Maria Isabel Carvalho +6 more
doaj +1 more source
Schematic representation of the genomes, characterization and VEGF-Trap protein of rNDV-VEGF-Trap.
, 2022 (A) Diagram showed insertion of the VEGF-Trap gene into the rNDV genomes at the position between the P and M genes. Recombinant NDV were rescued by transfecting BHK-21 cells with incorporated plasmid along with the helper plasmid PTM-NP, PTM-P and PTM-L.
Wei Xiao (16583) +8 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Digital Chinese Medicine, 2018 : Objective The effects of Shuang Dan Ming Mu capsule on expression of VEGF-a, VEGF-b, VEGF-c and the VEGF receptor, Flk-1, were examined in a diabetic retinopathy rats model.Methods Forty Sprague-Dawley (SD) rats were randomized into Groups A (blank), B
Jun PENG +4 more
doaj +1 more source
Open Medicine, 2023 Elevated serum uric acid (UA) level is related to type 2 diabetic retinopathy (DR). Vascular endothelial growth factor (VEGF), high-sensitivity C-reactive protein (hs-CRP), and cystatin C (Cys-C) have involvement in type 2 DR complicated with ...
Wei Jing +4 more
doaj +1 more source
Pharmacology Research & Perspectives, 2020 AbstractA phage‐derived human monoclonal antibody against VEGF‐C was developed as a potential anti‐tumor therapeutic and exhibited fast clearance in preclinical species, with notably faster clearance in serum than in plasma. The purpose of this work was to understand the factors contributing to its fast clearance.
Daniela Bumbaca Yadav +10 more
openaire +3 more sources