Results 31 to 40 of about 20,098,805 (300)

Alginate hydrogels allow for bioactive and sustained release of VEGF-C and VEGF-D for lymphangiogenic therapeutic applications. [PDF]

PLoS ONE, 2017
Lymphatic dysfunction is associated with the progression of many cardiovascular disorders due to their role in maintaining tissue fluid homeostasis.
Kevin T Campbell, Dustin J Hadley, David L Kukis, Eduardo A Silva   +3 more
doaj   +1 more source

Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis

Journal of Translational Medicine, 2017
Background The interaction of vascular endothelial growth factor-C (VEGF-C)/VEGF-D/VEGF receptor-3 is considered to be a major driver of lymphangiogenesis, however the mechanism of this process remains unclear.
Haruhisa Kitano, Joon-Yong Chung, Kyung Hee Noh, Young-Ho Lee, Tae Woo Kim, Seok Hyung Lee, Soo-Heang Eo, Hyung Jun Cho, Chel Hun Choi, Shuhei Inoue, Jun Hanaoka, Junya Fukuoka, Stephen M. Hewitt   +12 more
doaj   +1 more source

Expression of VEGF-C in Breast Carcinoma and its Association with HER2/neu and Oestrogen/Progesterone Receptors: A Cross-sectional Study [PDF]

National Journal of Laboratory Medicine, 2023
Introduction: Breast carcinoma is the most common malignant tumour and is the leading cause of carcinoma death in women. Assessing Vascular Endothelial Growth Factor-C (VEGF-C) is important because the expression of VEGF-C is one of the factors ...
Sohini Ray, Suman Ghosh, Sritanu Jana
doaj   +1 more source

Immunoreactivity of the anti-VEGF-A121 and anti-VEGF-A165 monoclonal antibodies.

, 2023
Mixture of rhVEGF-A121, rhVEGF-A165 and rhVEGF-A189 (50 μg each) were subjected to 15% SDS Polyacrylamide Gel Electrophoresis (SDS-PAGE). The transferred membrane was detected with anti-VEGF-A polyclonal antibody (left panel), anti-VEGF-A165 monoclonal ...
Yoko Oyama (600027), Aryal Bibek (15198524), Taiji Sakamoto (104961), Kazunori Takenouchi (15198521), Kazuhiko Higurashi (15198527), Shingo Yamada (339487), Hideaki Kanda (15198539), Akito Tabaru (15198530), Sadayuki Higashi (15198533), Hiroto Terasaki (104937), Chieko Fujisaki (15198536), Keiichi Inoue (466261), Masashi Okawa (8951294), Kiyonori Tanoue (14928179), Yoshiharu Soga (13883911), Munekazu Yamakuchi (220194), Teruto Hashiguchi (464609)   +16 more
core   +1 more source

Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics [PDF]

, 2014
Vascular endothelial growth factor-A (VEGF) is produced by most cancer cells as multiple isoforms, which display distinct biological activities. VEGF plays an undisputed role in tumour growth, vascularisation and metastasis; nevertheless the functions of
Reyes-Aldasoro, Constantino C., Steele, A.J., Constantino C Reyes-Aldasoro, Harris Sheila, English William R., English, W. R., Kanthou, Chryso, Diane V Lefley, Reyes-Aldasoro, C.C., Sheila Harris (77307), Reyes-Aldasoro Constantino C., Lefley, D. V., Dos Santos, S. A., Andrew J Steele, English, William R., Dachs, G. U., English, W.R., Steele Andrew J., Sheila Harris, Dachs Gabi U., Greco, Olga, Gillian M. Tozer (167783), Claudia Coralli-Foxon, Kanthou Chryso, Reyes-Aldasoro, C. C., William R English, Steele, Andrew J., Tozer, G. M., Gabi U Dachs, Coralli-Foxon, Claudia, Olga Greco (614634), Harris, S., Olga Greco, Andrew J. Steele (614632), Sofia A. Dos Santos (614635), Dachs, G.U., Dos Santos, S.A., Claudia Coralli-Foxon (614633), Harris, Sheila, Sofia A Dos Santos, Coralli-Foxon Claudia, Greco Olga, Tozer Gillian M., Chryso Kanthou, Gillian M Tozer, Tozer, Gillian M., William R. English (184202), Dos Santos Sofia A., Kanthou, C., Lefley, Diane V., Dos Santos, Sofia A., Chryso Kanthou (22774), Greco, O., Gabi U. Dachs (614630), Steele, A. J., Lefley, D.V., Diane V. Lefley (614631), Dachs, Gabi U., Constantino C. Reyes-Aldasoro (324791), Lefley Diane V., Coralli-Foxon, C., Tozer, G.M.   +61 more
core   +2 more sources

Heparanase induces VEGF C and facilitates tumor lymphangiogenesis [PDF]

International Journal of Cancer, 2008
AbstractHeparanase is an endoglycosidase that specifically cleaves heparan sulfate side chains, a class of glycosaminoglycans abundantly present in the extracellular matrix and on the cell surface. Heparanase activity is strongly implicated in tumor angiogenesis and metastasis attributed to remodeling of the subepithelial and subendothelial basement ...
Victoria, Cohen-Kaplan, Inna, Naroditsky, Anna, Zetser, Neta, Ilan, Israel, Vlodavsky, Ilana, Doweck   +5 more
openaire   +2 more sources

Mechanisms of vascular morphogenesis and stabilization by VEGF dose [PDF]

, 2014
VEGF is the master regulator of angiogenesis and the most investigated factor in therapeutic angiogenesis approaches to induce the growth of new vessels that could restore oxygen and nutrients supply in tissues affected by ischemia.
Groppa, Elena
core   +1 more source

Effect of High VEGF-C mRNA Expression on Achievement of Complete Remission in Adult Acute Myeloid Leukemia

Translational Oncology, 2018
Although vascular endothelial growth factor-C (VEGF-C) is known to be expressed in acute myeloid leukemia (AML) blasts, the relevance of VEGF-C in the clinical setting remains to be fully explored.
Sung-Eun Lee, Ji Yoon Lee, A-Reum Han, Hee-Sun Hwang, Woo-Sung Min, Hee-Je Kim   +5 more
doaj   +1 more source

Brain homeostasis : VEGF receptor 1 and 2 ; two unequal brothers in mind [PDF]

, 2013
Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the vascular system, exert trophic effects on neural cells during development and adulthood.
Karl H. Plate, Plate, Karl, Wittko-Schneider, Ina M., Schneider, Fabian T., Fabian T. Schneider, Ina M. Wittko-Schneider   +5 more
core   +1 more source

Critical requirement of VEGF-C in transition to fetal erythropoiesis [PDF]

Blood, 2016
Key Points Vegfc is essential for mobilization, maturation, and enucleation of primitive erythroblasts. Vegfc deletion compromises liver colonization by erythro-myeloid progenitors and subsequent macrophage/erythroid expansion.
Salminen Essi, Nurmi Harri, Alitalo Kari, Heinolainen Krista, Saharinen Pipsa, Fang Shentong, Chen Shuo, Salminen Essi, Nurmi Harri, Alitalo Kari, Heinolainen Krista, Saharinen Pipsa, Fang Shentong, Chen Shuo   +13 more
openaire   +2 more sources