Results 31 to 40 of about 14,728,452 (289)

The biophysical property of A549 cells transferred by VEGF‐D [PDF]

Scanning, 2013
SummaryVascular endothelial growth factor‐D (VEGF‐D) together with VEGF‐C is considered to be associated with lymphangiogenesis and angiogenesis and involve in tumorization. This study aims to investigate the influence of exogenous VEGF‐D gene on the biophysical property of cell surface of lung adenocarcinoma cell line.
Zhen, Wang, Xiu-Li, Wu, Xu, Wang, Hong-Xia, Tian, Zhi-Hong, Chen, Yang-Qiu, Li   +5 more
openaire   +2 more sources

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]

, 2003
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Shima, D., Christiana Ruhrberg, Betsholtz, C, Jeltsch, M, Abramsson, A., Shima, D, Matthew Golding, Lundkvist, A, Lundkvist, A., Golding, M, David Shima, Ruhrberg, C, Christopher Mitchell, Mitchell, C, Betsholtz, C., Kari Alitalo, Gerhardt, H, Ruhrberg, C., Christer Betsholtz, Golding, M., Jeltsch, M., Holger Gerhardt, Abramsson, A, Alitalo, K, Andrea Lundkvist, Fruttiger, M., Gerhardt, H., Alitalo, K., Alexandra Abramsson, Mitchell, C., Fruttiger, M, Michael Jeltsch, Marcus Fruttiger   +32 more
core   +1 more source

Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis

Journal of Translational Medicine, 2017
Background The interaction of vascular endothelial growth factor-C (VEGF-C)/VEGF-D/VEGF receptor-3 is considered to be a major driver of lymphangiogenesis, however the mechanism of this process remains unclear.
Haruhisa Kitano, Joon-Yong Chung, Kyung Hee Noh, Young-Ho Lee, Tae Woo Kim, Seok Hyung Lee, Soo-Heang Eo, Hyung Jun Cho, Chel Hun Choi, Shuhei Inoue, Jun Hanaoka, Junya Fukuoka, Stephen M. Hewitt   +12 more
doaj   +1 more source

Immunoreactivity of the anti-VEGF-A121 and anti-VEGF-A165 monoclonal antibodies.

, 2023
Mixture of rhVEGF-A121, rhVEGF-A165 and rhVEGF-A189 (50 μg each) were subjected to 15% SDS Polyacrylamide Gel Electrophoresis (SDS-PAGE). The transferred membrane was detected with anti-VEGF-A polyclonal antibody (left panel), anti-VEGF-A165 monoclonal ...
Yoko Oyama (600027), Aryal Bibek (15198524), Taiji Sakamoto (104961), Kazunori Takenouchi (15198521), Kazuhiko Higurashi (15198527), Shingo Yamada (339487), Hideaki Kanda (15198539), Akito Tabaru (15198530), Sadayuki Higashi (15198533), Hiroto Terasaki (104937), Chieko Fujisaki (15198536), Keiichi Inoue (466261), Masashi Okawa (8951294), Kiyonori Tanoue (14928179), Yoshiharu Soga (13883911), Munekazu Yamakuchi (220194), Teruto Hashiguchi (464609)   +16 more
core   +1 more source

Effect of vascular endothelial growth factors A, C, and D in HIV-associated pre-eclampsia

Hypertension in Pregnancy, 2017
Objective: To measure and correlate the level of vascular endothelial growth factors A, C, and D in HIV-associated pre-eclampsia. Methods: VEGF-A, VEGF-C, and VEGF-D were measured in serum of 76 normotensive and pre-eclamptic pregnant women stratified by
Gugulethu Promise Shange, Jagidesa Moodley, Thajasvarie Naicker   +2 more
doaj   +1 more source

Correlation between tear levels of vascular endothelial growth factor and vitamin D at retinopathy of prematurity stages in preterm infants

Scientific Reports, 2023
Deregulation of vascular endothelial growth factor (VEGF) levels leads to retinopathy of prematurity (ROP). Vitamin D (VIT-D) is known to regulate VEGF in an oxygen dependent manner.
Ponnalagu Murugeswari, Anand Vinekar, S. Grace Prakalapakorn, Venkata Ramana Anandula, Murali Subramani, Tanuja Arun Vaidya, Archana Padmanabhan Nair, Chaitra Jayadev, Arkasubhra Ghosh, Govindasamy Kumaramanickavel, Rohit Shetty, Debashish Das   +11 more
doaj   +1 more source

Mechanisms of vascular morphogenesis and stabilization by VEGF dose [PDF]

, 2014
VEGF is the master regulator of angiogenesis and the most investigated factor in therapeutic angiogenesis approaches to induce the growth of new vessels that could restore oxygen and nutrients supply in tissues affected by ischemia.
Groppa, Elena
core   +1 more source

Molecular Characterization and Interaction between Human VEGF-D and VEGFR-3. [PDF]

J Microbiol Biotechnol
Angiogenesis and lymphangiogenesis are some of the routes that cause metastasis. Vascular Endothelial Growth Factors (VEGFs) stimulate angiogenesis and lymphangiogenesis through VEGF receptors. Especially, VEGF-D and its receptor, VEGFR-3, play a pivotal role in regulating cellular processes such as survival, proliferation, and migration, thereby ...
Seo CE, Lee HN, Jeong MS, Jang SB.
europepmc   +3 more sources

VEGF-D(ilated) Lymphatics as Gateways to Metastasis [PDF]

Cancer Cell, 2012
VEGF-C and VEGF-D have been implicated in lymphatic metastasis, mainly as inducers of new intra/peritumoral capillary lymphatics. In this issue of Cancer Cell, Karnezis and colleagues challenge this notion and demonstrate that tumor-derived VEGF-D promotes metastasis by causing prostaglandin-dependent dilation of collecting lymphatics outside of the ...
openaire   +2 more sources

Serum vascular endothelial growth factor-D as a diagnostic and therapeutic biomarker for lymphangioleiomyomatosis.

PLoS ONE, 2019
BackgroundIn lymphangioleiomyomatosis (LAM), tuberous sclerosis gene mutations activate the mechanistic target of the rapamycin pathway, resulting in vascular endothelial growth factor-D (VEGF-D) overproduction.
Masaki Hirose, Akiko Matsumuro, Toru Arai, Chikatoshi Sugimoto, Masanori Akira, Masanori Kitaichi, Lisa R Young, Francis X McCormack, Yoshikazu Inoue   +8 more
doaj   +1 more source