Results 231 to 240 of about 2,608,192 (371)

Drug Delivery Technologies for the Treatment of Age‐Related Macular Degeneration

Advanced Science, EarlyView.
There are multiple therapeutic agents available for the treatment of both dry age‐related macular degeneration (AMD) and wet AMD. It is essential to continue innovation by introducing new drug delivery technologies that can incorporate those along with patient compliance and the accessibility of the technology into the early stages of research and ...
J Jesus Rodriguez‐Cruz, Jessica Cutrufello, Michael Lam, Shreya Nallaparaju, Nicholas A. Peppas   +4 more
wiley   +1 more source

Expression of vascular endothelial growth factor (VEGF) receptors in rat corpus luteum: regulation by oestradiol during mid-pregnancy [PDF]

, 2001
Norihiro Sugino, Shiro Kashida, Shuji Takiguchi, Ayako Karube-Harada, Hiroshi Kato   +4 more
openalex   +1 more source

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

Advanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu, Liting Huang, Suzhen Bi, WeiKaixin Kong, Wanting Feng, Yingjia Li, Zhengwei Xie, Peipei Shan, Sujie Zhu   +8 more
wiley   +1 more source

VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation.

AJP - Renal Physiology, 2008
M. Saban, J. Backer, M. Backer, J. Maier, Ben Fowler, C. Davis, Cindy Simpson, Xue-Ru Wu, L. Birder, M. Freeman, S. Soker, R. Hurst, Ricardo Saban   +12 more
semanticscholar   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1 [PDF]

, 2002
James Bainbridge, Ajay Mistry, M. De Alwis, Ewa Paleolog, Andrew H. Baker, AJ Thrasher, Robin R. Ali   +6 more
openalex   +1 more source

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Soluble VEGF receptor Flt1: the elusive preeclampsia factor discovered? [PDF]

, 2003
Aernout Luttun, Peter Carmeliet
openalex   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients.

AJP - Renal Physiology, 2008
Ricardo Saban, M. Saban, J. Maier, Ben Fowler, M. Tengowski, C. Davis, Xue-Ru Wu, D. Culkin, P. Hauser, J. Backer, R. Hurst   +10 more
semanticscholar   +1 more source