Results 61 to 70 of about 38,232 (251)

A Tricky Trait: Applying the Fruits of the “Function Debate” in the Philosophy of Biology to the “Venom Debate” in the Science of Toxinology

open access: yesToxins, 2016
The “function debate” in the philosophy of biology and the “venom debate” in the science of toxinology are conceptually related. Venom systems are complex multifunctional traits that have evolved independently numerous times throughout the animal kingdom.
Timothy N. W. Jackson, Bryan G. Fry
doaj   +1 more source

A nanobody-derived mimotope against VEGF inhibits cancer angiogenesis

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Vascular Endothelial Growth Factor (VEGF) promotes angiogenesis in tumours of various cancers. Monoclonal antibodies and nanobodies are one of the potent agents in the treatment of cancer.
Elmira Karami   +4 more
doaj   +1 more source

Predation on a pygmy shrew, Sorex minutus, by the noble false widow spider, Steatoda nobilis

open access: yesEcosphere, 2023
The noble false widow spider Steatoda nobilis is a globally invasive species with implications for public health and possibly for native ecosystems. Here, we report on a case of predation on a protected species of vertebrate, a pygmy shrew Sorex minutus ...
Michel M. Dugon   +3 more
doaj   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

open access: yesAdvanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang   +14 more
wiley   +1 more source

A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms

open access: yesFrontiers in Immunology, 2021
Rattlesnakes are a diverse clade of pit vipers (snake family Viperidae, subfamily Crotalinae) that consists of numerous medically significant species.
Lorenzo Seneci   +10 more
doaj   +1 more source

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

open access: yesAdvanced Materials, EarlyView.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew   +2 more
wiley   +1 more source

Advancing Metal–Organic Framework‐Based Composites for Effective Chemical Warfare Agent Detoxification under Real‐World Conditions

open access: yesAdvanced Materials, EarlyView.
This review describes recent developments in the design and synthesis of metal–organic frameworks (MOF)/textile composites for the detoxification of chemical warfare agent and simulants with extensive discussion on the advantages and disadvantages of different methods.
Zhihua Cheng   +4 more
wiley   +1 more source

An Appetite for Destruction: Detecting Prey-Selective Binding of α-Neurotoxins in the Venom of Afro-Asian Elapids

open access: yesToxins, 2020
Prey-selective venoms and toxins have been documented across only a few species of snakes. The lack of research in this area has been due to the absence of suitably flexible testing platforms.
Richard J. Harris   +4 more
doaj   +1 more source

Environmental Sustainability of Natural Biopolymer‐Based Electrolytes for Lithium Ion Battery Applications

open access: yesAdvanced Materials, EarlyView.
Twenty‐one biopolymer electrolytes including membrane‐liquid electrolytes, gel electrolytes, and solid electrolytes are synthesized to analyze their electrochemical properties and environmental impacts through life cycle assessment. This consistent and comparable study demonstrates the significant functional and environmental benefits of biopolymer ...
Jing Huang   +4 more
wiley   +1 more source

An overview on application of phage display technique in immunological studies

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2017
Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami   +4 more
doaj   +1 more source

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