Results 31 to 40 of about 119,167 (203)

Investigating Toxin Diversity and Abundance in Snake Venom Proteomes [PDF]

open access: yesFrontiers in Pharmacology, 2022
Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development. To explore the current state of snake venom proteomics and transcriptomics we investigated venom proteomic methods, associations between methodological and
Tasoulis, T.   +2 more
openaire   +4 more sources

Fast venomic analysis of Crotalus durissus terrificus from northeastern Argentina

open access: yesToxicon: X, 2020
The complete knowledge of the toxins that make up venoms is the base for the treatment of snake accidents victims and the selection of specimens for the preparation of venom pools for antivenom production. In this work, we used a fast and direct venomics
Luciano S. Fusco   +6 more
doaj   +1 more source

Transcriptome and venom proteome of the box jellyfish Chironex fleckeri. [PDF]

open access: yesBMC Genomics, 2015
The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe localized and systemic effects that are potentially life-threatening. In this study, a combined transcriptomic and proteomic approach was used to identify C.
Brinkman DL   +6 more
europepmc   +7 more sources

Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah). [PDF]

open access: yesBMC Genomics, 2015
The king cobra (Ophiophagus hannah) is widely distributed throughout many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus hannah (MOh) venom for a better understanding of king cobra venom variation and its envenoming pathophysiology. The venom gland transcriptome was investigated using the Illumina HiSeq™ platform,
Tan CH, Tan KY, Fung SY, Tan NH.
europepmc   +4 more sources

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

open access: yes, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ   +47 more
core   +1 more source

Translational Venomics: Third-Generation Antivenomics of Anti-Siamese Russell’s Viper, Daboia siamensis, Antivenom Manufactured in Taiwan CDC’s Vaccine Center

open access: yesTropical Medicine and Infectious Disease, 2018
The venom proteome of Siamese Russell’s viper from Taiwan, alongside complementary in vivo lethality neutralization assay and in vitro third-generation antivenomics assessment of the preclinical efficacy of the homologous antivenom manufactured in ...
Libia Sanz   +5 more
doaj   +1 more source

Clinical effectiveness of hymenoptera venom immunotherapy [PDF]

open access: yes, 2013
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Scheipl, Fabian   +21 more
core   +1 more source

Venomic Analysis of the Poorly Studied Desert Coral Snake, Micrurus tschudii tschudii, Supports the 3FTx/PLA2 Dichotomy across Micrurus Venoms

open access: yesToxins, 2016
The venom proteome of the poorly studied desert coral snake Micrurus tschudii tschudii was unveiled using a venomic approach, which identified ≥38 proteins belonging to only four snake venom protein families.
Libia Sanz   +7 more
doaj   +1 more source

Pharmacological aspects of Vipera xantina palestinae venom [PDF]

open access: yes, 2011
In Israel, Vipera xantina palestinae (V.x.p.) is the most common venomous snake, accounting for several hundred cases of envenomation in humans and domestic animals every year, with a mortality rate of 0.5 to 2%.
Katzhendler, Jeoshua   +14 more
core   +1 more source

Comparative Analysis of the Venom Proteins from Two Eupelmid Egg Parasitoids Anastatus japonicus and Mesocomys trabalae

open access: yesBiology, 2023
Parasitic wasps are abundant and diverse Hymenoptera insects that lay their eggs inside or on the external surface of the host and inject venom into the host to create a more favorable environment for the larvae to survive and regulate the host’s ...
Qian-Yu Zhao   +4 more
doaj   +1 more source

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