Results 51 to 60 of about 119,167 (203)

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

Toxins, 2020
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
Luciana A. Freitas-de-Sousa, Pedro G. Nachtigall, José A. Portes-Junior, Matthew L. Holding, Gunnar S. Nystrom, Schyler A. Ellsworth, Noranathan C. Guimarães, Emilly Tioyama, Flora Ortiz, Bruno R. Silva, Tobias S. Kunz, Inácio L. M. Junqueira-de-Azevedo, Felipe G. Grazziotin, Darin R. Rokyta, Ana M. Moura-da-Silva   +14 more
doaj   +1 more source

Proteomic Characterization of the Venom Of Five Bombus (Thoracobombus) Species [PDF]

Toxins, 2017
Abstract Venomous animals use venom; a complex biofluid composed of unique mixtures of proteins and peptides, to act on vital systems of the prey or predator. In bees, venom is solely used for defense against predators. However, the venom composition of bumble bees ( Bombus sp. ) is
Barkan, Nezahat Pinar, Bayazit, Mustafa Bilal, Demiralp Özel, Duygu   +2 more
openaire   +6 more sources

Vintage venoms: Proteomic and pharmacological stability of snake venoms stored for up to eight decades [PDF]

Journal of Proteomics, 2014
For over a century, venom samples from wild snakes have been collected and stored around the world. However, the quality of storage conditions for "vintage" venoms has rarely been assessed. The goal of this study was to determine whether such historical venom samples are still biochemically and pharmacologically viable for research purposes, or if new ...
Jesupret, Clémence, Baumann, Kate, Jackson, Timothy N. W., Ali, Syed Abid, Yang, Daryl C., Greisman, Laura, Kern, Larissa, Steuten, Jessica, Jouiaei, Mahdokht, Casewell, Nicholas R., Undheim, Eivind A. B., Koludarov, Ivan, Debono, Jordan, Low, Dolyce H. W., Rossi, Sarah, Panagides, Nadya, Winter, Kelly, Ignjatovic, Vera, Summerhayes, Robyn, Jones, Alun, Nouwens, Amanda, Dunstan, Nathan, Hodgson, Wayne C., Winkel, Kenneth D., Monagle, Paul, Fry, Bryan Grieg   +25 more
openaire   +5 more sources

Biological characterization of Bothrops marajoensis snake venom

, 2011
This study describes the effects of Bothrops marajoensis venom (Marajó lancehead) on isolated neuromuscular preparations of chick biventer cervicis (CBC) and mouse phrenic nerve-diaphragm (PND).
Marangoni, Sérgio, Pai-Silva, Maeli Dal, Gallacci, Márcia, Cruz-Höfling, Maria Alice da, Randazzo-Moura, Priscila, Galbiatti, Charlene, Ponce-Souto, Luis, Hernadez-Oliveira, Saraguaci, Rocha, Thalita, Cavalcante, Walter Luiz Garrido, Rodrigues-Simioni, Léa   +10 more
core   +3 more sources

Proteomic Investigation of Cape Cobra (Naja nivea) Venom Reveals First Evidence of Quaternary Protein Structures

Toxins
Naja nivea (N. nivea) is classed as a category one snake by the World Health Organization since its envenomation causes high levels of mortality and disability annually. Despite this, there has been little research into the venom composition of N. nivea,
Lewis O. McFarlane, Tara L. Pukala
doaj   +1 more source

First Look at the Venom of Naja ashei

Molecules, 2018
Naja ashei is an African spitting cobra species closely related to N. mossambica and N. nigricollis. It is known that the venom of N. ashei, like that of other African spitting cobras, mainly has cytotoxic effects, however data about its specific protein
Konrad Kamil Hus, Justyna Buczkowicz, Vladimír Petrilla, Monika Petrillová, Andrzej Łyskowski, Jaroslav Legáth, Aleksandra Bocian   +6 more
doaj   +1 more source

Canopy Venom: Proteomic Comparison among New World Arboreal Pit-Viper Venoms [PDF]

Toxins, 2016
Central and South American pitvipers, belonging to the genera Bothrops and Bothriechis, have independently evolved arboreal tendencies. Little is known regarding the composition and activity of their venoms. In order to close this knowledge gap, venom proteomics and toxin activity of species of Bothriechis, and Bothrops (including Bothriopsis) were ...
Jordan Debono, Chip Cochran, Sanjaya Kuruppu, Amanda Nouwens, Niwanthi Rajapakse, Minami Kawasaki, Kelly Wood, James Dobson, Kate Baumann, Mahdokht Jouiaei, Timothy Jackson, Ivan Koludarov, Dolyce Low, Syed Ali, A. Smith, Andrew Barnes, Bryan Fry   +16 more
openaire   +6 more sources

Proteomic Characterization and Comparison of Malaysian Tropidolaemus wagleri and Cryptelytrops purpureomaculatus Venom Using Shotgun-Proteomics

Toxins, 2016
Tropidolaemus wagleri and Cryptelytrops purpureomaculatus are venomous pit viper species commonly found in Malaysia. Tandem mass spectrometry analysis of the crude venoms has detected different proteins in T. wagleri and C. purpureomaculatus.
Syafiq Asnawi Zainal Abidin, Pathmanathan Rajadurai, Md Ezharul Hoque Chowdhury, Muhamad Rusdi Ahmad Rusmili, Iekhsan Othman, Rakesh Naidu   +5 more
doaj   +1 more source

Integration of transcriptomic and proteomic approaches for snake venom profiling

Expert Review of Proteomics, 2021
Snake venoms contain many protein and peptide isoforms with high levels of sequence variation, even within a single species. In this review, we highlight several examples, from both published and unpublished work in our lab, demonstrating how a combined venom gland transcriptome and proteome methodology allows for comprehensive characterization of ...
Cassandra M, Modahl, Anthony J, Saviola, Stephen P, Mackessy   +2 more
openaire   +3 more sources

Missiles of Mass Disruption: Composition and Glandular Origin of Venom Used as a Projectile Defensive Weapon by the Assassin Bug Platymeris rhadamanthus

Toxins, 2019
Assassin bugs (Reduviidae) produce venoms that are insecticidal, and which induce pain in predators, but the composition and function of their individual venom components is poorly understood.
Andrew A. Walker, Samuel D. Robinson, Eivind A. B. Undheim, Jiayi Jin, Xiao Han, Bryan G. Fry, Irina Vetter, Glenn F. King   +7 more
doaj   +1 more source