Results 71 to 80 of about 119,167 (203)

Dynamic Rearrangement in Snake Venom Gland Proteome: Insights into Bothrops jararaca Intraspecific Venom Variation

, 2016
We carried out an analysis of the venom gland proteome of Bothrops jararaca taking into account two distinct phases of its ontogenetic development (i.e., newborn and adult) and the marked sexual dimorphism recently reported on its venom proteome ...
Débora Andrade-Silva (2869070), Solange M. T. Serrano (2118343), Isabella Fukushima (3113661), André Zelanis (1743517), César Augusto-de-Oliveira (3113667), Eduardo S. Kitano (1743514), Tarcísio Liberato (3113670), Daniel R. Stuginski (3113664)   +7 more
core   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

Insect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo, João Alfredo Teodoro, Danilo T. Amaral   +2 more
wiley   +1 more source

The host range paradox of Meloidogyne incognita: a physiological and transcriptomic analysis of nine susceptible interactions across six plant orders

New Phytologist, EarlyView.
Phylogenetic distance of host does not explain phenotypic differences of Meloidogyne incognita parasitism at 25 dpi. Summary The plant–parasitic nematode Meloidogyne incognita is the pathogen with the broadest host range among all known biotrophic interactions.
Victor Hugo Moura de Souza, Clement Pellegrin, Vincent C. T. Hanlon, Chongjing Xia, Olaf P. Kranse, Unnati Sonawala, Priya Desikan, Beatrice Senatori, Lucie Bolelli, Etienne G. J. Danchin, Lida Derevnina, Sebastian Eves‐van den Akker   +11 more
wiley   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Jacoby-Alner, T.E., Davern, K.M., Swindells, K., Stephens, N., Balmer, L., Brown, S.G.A.   +5 more
core  

Data from: Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

, 2015
Background: The king cobra (Ophiophagus hannah) is widely distributed throughout many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus hannah (MOh) venom for a better understanding of king cobra venom variation and ...
Tan, Kae Yi, Tan, Choo Hock, Fung, Shin Yee, Tan, Nget Hong   +3 more
core   +1 more source

In-Depth Venome of the Brazilian Rattlesnake Crotalus durissus terrificus: An Integrative Approach Combining Its Venom Gland Transcriptome and Venom Proteome

, 2018
Snake venoms are complex mixtures mainly composed of proteins and small peptides. Crotoxin is one of the most studied components from Crotalus venoms, but many other components are less known due to their low abundance.
Romualdo Morandi Filho (5859167), Edwin De Pauw (92028), Carlos Ueira-Vieira (788971), Camila T. Cologna (5859164), Gisele A. Wiezel (5859158), Eliane C. Arantes (5148548), Loïc Quinton (1598419), Priscila Y. T. Shibao (5859161)   +7 more
core   +2 more sources

Elucidating the Venom Diversity in Sri Lankan Spectacled Cobra (Naja naja) through De Novo Venom Gland Transcriptomics, Venom Proteomics and Toxicity Neutralization

Toxins, 2021
Inadequate effectiveness of Indian antivenoms in treating envenomation caused by the Spectacled Cobra/Indian Cobra (Naja naja) in Sri Lanka has been attributed to geographical variations in the venom composition. This study investigated the de novo venom-
Kin Ying Wong, Kae Yi Tan, Nget Hong Tan, Christeine Ariaranee Gnanathasan, Choo Hock Tan   +4 more
doaj   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Proteomic profiling of snake venom metalloproteinases (SVMPs): Insights into venom induced pathology

Toxicon, 2009
Bothrops sp. snakebites account for the majority of envenomations in South and Central America. Bothrops jararaca accidents are characterized by edema, hemorrhage and necrosis, mainly attributed to the action of hemorrhagic snake venom metalloproteinases (SVMPs).
Renata M S, Terra, Antônio F M, Pinto, Jorge A, Guimarães, Jay W, Fox   +3 more
openaire   +2 more sources

Venom composition of Trimeresurus albolabris, T. insularis, T. puniceus and T. purpureomaculatus from Indonesia

Journal of Venomous Animals and Toxins including Tropical Diseases, 2022
Background: Several studies have been published on the characterization of Trimeresurus venoms. However, there is still limited information concerning the venom composition of Trimeresurus species distributed throughout Indonesia, which contributes to ...
Syahfitri Anita, Arif Rahman Sadjuri, Latri Rahmah, Herjuno Ari Nugroho, Mulyadi, Wahyu Trilaksono, Wiwit Ridhani, Nabila Safira, Hariman Bahtiar, Maharani, Amir Hamidy, Adriansjah Azhari   +11 more
doaj   +1 more source