Results 81 to 90 of about 119,167 (203)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Additional file 3: of Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

, 2016
Malaysian Ophiophagus hannah venom proteome.
Choo Tan (3514394), Kae Tan (3514397), Shin Fung (3514391), Nget Tan (3514400)   +3 more
core   +1 more source

The Dual Prey-Inactivation Strategy of Spiders—In-Depth Venomic Analysis of Cupiennius salei

Toxins, 2019
Most knowledge of spider venom concerns neurotoxins acting on ion channels, whereas proteins and their significance for the envenomation process are neglected.
Lucia Kuhn-Nentwig, Nicolas Langenegger, Manfred Heller, Dominique Koua, Wolfgang Nentwig   +4 more
doaj   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Multi‐Omics Analysis Reveals That Aβ42‐ Me3 Co‐Aggregation Induces Mitophagy Blockade in Early Stages of Alzheimer's Disease

MedComm, Volume 7, Issue 9, September 2026.
Using multi‐omics techniques, including proteomics, targeted metabolomics, and structural proteomics, we observed that the early stage of Alzheimer's disease (AD) progression was accompanied by mitochondrial dysfunction aggravation, the entry of excessive Aβ into the mitochondria, and the co‐aggregation of Aβ and Me3 protein, thus inducing ...
Wenjie Zhu, Yuanyuan Zhang, Pengjie Li, Yingying Zhong, Yawei Lin, Xin Liu   +5 more
wiley   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
Rueff, F., Wagner, N., Hagedorn, M., Przybilla, Bernhard, Fritze, D.   +4 more
core   +1 more source

Firing the Sting: Chemically Induced Discharge of Cnidae Reveals Novel Proteins and Peptides from Box Jellyfish (Chironex fleckeri) Venom

Toxins, 2015
Cnidarian venom research has lagged behind other toxinological fields due to technical difficulties in recovery of the complex venom from the microscopic nematocysts.
Mahdokht Jouiaei, Nicholas R. Casewell, Angel A. Yanagihara, Amanda Nouwens, Bronwen W. Cribb, Darryl Whitehead, Timothy N. W. Jackson, Syed A. Ali, Simon C. Wagstaff, Ivan Koludarov, Paul Alewood, Jay Hansen, Bryan G. Fry   +12 more
doaj   +1 more source

Edible Insect Allergens: An Emerging Food Safety Challenge

Sustainable Food Proteins, Volume 4, Issue 3, September 2026.
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu, Cassandra Maya, John J. Love, Huilian Che, Ke Chen, Jing Zhao   +5 more
wiley   +1 more source

venom

, 2018
MALDI-TOF MS and SDS-PAGE data of venom of sampled ...
Ondrej Bocanek (5672750), Stano Pekar (3257067), Liznarova, Eva, Zdrahal, Zbynek, Bocanek, Ondrej, Eva Liznarova (5672747), Zbynek Zdrahal (683821), Pekar, Stano   +7 more
core   +1 more source